Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Carina M. L. Delpiccolo"'
1
Akademický článek
Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro
Autor: Santiago M. Ruatta, Denis N. Prada Gori, Martín Fló Díaz, Franca Lorenzelli, Karen Perelmuter, Lucas N. Alberca, Carolina L. Bellera, Andrea Medeiros, Gloria V. López, Mariana Ingold, Williams Porcal, Estefanía Dibello, Irina Ihnatenko, Conrad Kunick, Marcelo Incerti, Martín Luzardo, Maximiliano Colobbio, Juan Carlos Ramos, Eduardo Manta, Lucía Minini, María Laura Lavaggi, Paola Hernández, Jonas Šarlauskas, César Sebastian Huerta García, Rafael Castillo, Alicia Hernández-Campos, Giovanni Ribaudo, Giuseppe Zagotto, Renzo Carlucci, Noelia S. Medrán, Guillermo R. Labadie, Maitena Martinez-Amezaga, Carina M. L. Delpiccolo, Ernesto G. Mata, Laura Scarone, Laura Posada, Gloria Serra, Theodora Calogeropoulou, Kyriakos Prousis, Anastasia Detsi, Mauricio Cabrera, Guzmán Alvarez, Adrián Aicardo, Verena Araújo, Cecilia Chavarría, Lucija Peterlin Mašič, Melisa E. Gantner, Manuel A. Llanos, Santiago Rodríguez, Luciana Gavernet, Soonju Park, Jinyeong Heo, Honggun Lee, Kyu-Ho Paul Park, Mariela Bollati-Fogolín, Otto Pritsch, David Shum, Alan Talevi, Marcelo A. Comini
Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The identification of chemical compounds that interfere with SARS-CoV-2 replication continues to be a priority in several academic and pharmaceutical laboratories. Computational tools and approaches have the power to integrate, process
Externí odkaz: https://doaj.org/article/37a7aaacc38c4e40801eaddd5b8743ba
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2
Akademický článek
A Penicillin Derivative Exerts an Anti-Metastatic Activity in Melanoma Cells Through the Downregulation of Integrin αvβ3 and Wnt/β-Catenin Pathway
Autor: Elizabeth Barrionuevo, Florencia Cayrol, Graciela A. Cremaschi, Patricia G. Cornier, Dora B. Boggián, Carina M. L. Delpiccolo, Ernesto G. Mata, Leonor P. Roguin, Viviana C. Blank
Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)
The synthetic triazolylpeptidyl penicillin derivative, named TAP7f, has been previously characterized as an effective antitumor agent in vitro and in vivo against B16-F0 melanoma cells. In this study, we investigated the anti-metastatic potential of
Externí odkaz: https://doaj.org/article/aa779f640d1a4392bc3ab33af106ce02
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5
Contribution of endoplasmic reticulum stress, MAPK and PI3K/Akt pathways to the apoptotic death induced by a penicillin derivative in melanoma cells
Autor: Ernesto G. Mata, Patricia G. Cornier, Juan Manuel Anselmi Relats, Yanina Bellizzi, Florencia Cayrol, Graciela Cremaschi, Carina M. L. Delpiccolo, Viviana C. Blank, Leonor P. Roguin
Publikováno v: Apoptosis. 2022, 27 (1-2)
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Bellizzi, Yanina. Universidad de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Facultad de Farmacia y Bioquímica. Laboratorio de Oncología y Transducción de Señales. Instituto de Química y Fisicoquímica Bioló
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d625eef6ed7f95bd0c9f7913b588323
https://doi.org/10.1007/s10495-021-01697-7
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8
Contribution of endoplasmic reticulum stress, MAPK and PI3K/Akt pathways to the apoptotic death induced by a penicillin derivative in melanoma cells
Autor: Yanina, Bellizzi, Juan Manuel, Anselmi Relats, Patricia G, Cornier, Carina M L, Delpiccolo, Ernesto G, Mata, Florencia, Cayrol, Graciela A, Cremaschi, Viviana C, Blank, Leonor P, Roguin
Publikováno v: Apoptosis : an international journal on programmed cell death. 27(1-2)
We have previously examined the in vitro and in vivo antitumor action of TAP7f, a synthetic triazolylpeptidyl penicillin, on murine melanoma cells. In this work, we explored the signal transduction pathways modulated by TAP7f in murine B16-F0 and hum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::496a10638259a770a5f654d8ed09480a
https://pubmed.ncbi.nlm.nih.gov/34773171
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9
Synthesis of propargylamines via the A
Autor: Maitena, Martinez-Amezaga, Rocío A, Giordano, Denis N, Prada Gori, Caterina, Permingeat Squizatto, María V, Giolito, O Graciela, Scharovsky, Viviana R, Rozados, María J, Rico, Ernesto G, Mata, Carina M L, Delpiccolo
Publikováno v: Organicbiomolecular chemistry. 18(13)
Propargylamines have gained importance in the area of anticancer research. We synthesized 1-substituted propargylic tertiary amines using the A3-coupling as the key step. Both, solution and solid-phase protocols, were used to provide a library of 1-s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c82b33b0c706e35b868e22130fb34184
https://pubmed.ncbi.nlm.nih.gov/32182329
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