Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Carina M, Rivolta"'
Autor:
Sofia Siffo, Mauricio Gomes Pio, Elena Bueno Martínez, Katherine Lachlan, Joanna Walker, Jacques Weill, Rogelio González-Sarmiento, Carina M. Rivolta, Héctor M. Targovnik
Thyroglobulin (TG), the predominant glycoprotein of the thyroid gland, functions as matrix protein in thyroid hormonegenesis. TG deficiency results in thyroid dyshormonogenesis. These variants produce a heterogeneous spectrum of congenital goitre, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc9c15f53de688bd83a5f5679ac4697
https://doi.org/10.21203/rs.3.rs-2167457/v1
https://doi.org/10.21203/rs.3.rs-2167457/v1
Autor:
Mauricio Gomes Pio, Ezequiela Adrover, Mirta B. Miras, Gabriela Sobrero, Maricel F. Molina, Karen G. Scheps, Carina M. Rivolta, Héctor M. Targovnik
Publikováno v:
Molecular and Cellular Endocrinology. 572:111948
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::446b8d8194cf51f5e9c82c49ade5a682
https://doi.org/10.1016/j.mce.2023.111948
https://doi.org/10.1016/j.mce.2023.111948
Autor:
Maricel F. Molina, Sofia Siffo, Ezequiela Adrover, Héctor M. Targovnik, Miguel Martin Abelleyro, Karen G. Scheps, Mauricio Gomes Pio, Carina M. Rivolta
Publikováno v:
Molecular and cellular endocrinology. 534
Thyroglobulin (TG) is a large glycosylated protein of 2767 amino acids, secreted by the thyrocytes into the follicular lumen. It plays an essential role in the process of thyroid hormone synthesis. TG gene variants lead to permanent congenital hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fdac2a53fa708c79cc8ee745dd9af7
https://pubmed.ncbi.nlm.nih.gov/34119605
https://pubmed.ncbi.nlm.nih.gov/34119605
Autor:
Maricel F. Molina, Mauricio Gomes Pio, Carina M. Rivolta, Ana Chiesa, Sofia Siffo, Héctor M. Targovnik
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Thyroglobulin (TG) is a homodimeric glycoprotein synthesized by the thyroid gland. To date, two hundred twenty-seven variations of the TG gene have been identified in humans. Thyroid dyshormonogenesis due to TG gene mutations have an estimated incide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86e217b06104dcabd11306ba2c1b6eb
https://linkinghub.elsevier.com/retrieve/pii/S0303720720304263
https://linkinghub.elsevier.com/retrieve/pii/S0303720720304263
Publikováno v:
Molecular and cellular endocrinology. 528
Thyroglobulin (TG) plays a main role in the biosynthesis of thyroid hormones (TH), and, thus, it is involved in a wide range of vital functions throughout the life cycle of all vertebrates. Deficiency of TH production due to TG genetic variants cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d854d596fae975033ece537cc924aef
https://pubmed.ncbi.nlm.nih.gov/33689781
https://pubmed.ncbi.nlm.nih.gov/33689781
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 31:195-212
Iodide Handling Disorders lead to defects of the biosynthesis of thyroid hormones (thyroid dyshormonogenesis, TD) and thereafter congenital hypothyroidism (CH), the most common endocrine disease characterized by low levels of circulating thyroid horm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efe11aec5db028d5b24d286db6092af
https://doi.org/10.1016/j.beem.2017.03.006
https://doi.org/10.1016/j.beem.2017.03.006
Primary congenital hypothyroidism (CH) is the most commonendocrine disease in children and one of the most common preventablecauses of both cognitive and motor deficits. CH is a heterogeneous groupof thyroid disorders in which inadequate production o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ea979fff21b8d5113108541ace476f
https://www.sciencedirect.com/science/article/pii/S0303720719303405
https://www.sciencedirect.com/science/article/pii/S0303720719303405
Publikováno v:
Open Journal of Biological Sciences. :062-070
Dyshormonogenesis due to thyroglobulin (TG) gene mutations is a rare cause of congenital hypothyroidism with an estimated incidence of approximately 1 in 100,000 newborns.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81e8ca7d4bfe636b71a5d122a9745409
https://doi.org/10.17352/ojbs.000006
https://doi.org/10.17352/ojbs.000006
Autor:
Carina M. Rivolta, Cintia E. Citterio, Gabriela Sobrero, Graciela Testa, Mirta Miras, Fiorella Sabrina Belforte, Héctor M. Targovnik, María Cecilia Olcese
Publikováno v:
Molecular and Cellular Endocrinology. 419:172-184
Iodide Organification defects (IOD) represent 10% of cases of congenital hypothyroidism (CH) being the main genes affected that of TPO (thyroid peroxidase) and DUOX2 (dual oxidasa 2). From a patient with clinical and biochemical criteria suggestive w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5c0f0eb8d8546ae67f020d06145e78
https://doi.org/10.1016/j.mce.2015.10.014
https://doi.org/10.1016/j.mce.2015.10.014
Autor:
Peter Arvan, Karen G. Scheps, Héctor M. Targovnik, Cintia E. Citterio, Osvaldo Rey, Sofia Siffo, Christian M. Moya, Maricel F. Molina, Carina M. Rivolta, Mauricio Gomes Pio
Publikováno v:
Molecular and Cellular Endocrinology. 505:110719
Thyroglobulin (TG), a large glycosylated protein secreted by thyrocytes into the thyroid follicular lumen, plays an essential role in thyroid hormone biosynthesis. Rattus norvegicus TG (rTG) is encoded by a large single copy gene, 186-kb long, locate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6beb7c449d3b49ad8cddb29df2961625
https://doi.org/10.1016/j.mce.2020.110719
https://doi.org/10.1016/j.mce.2020.110719