Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carina L. Bos"'
Autor:
Tita Ritsema, David Brodmann, Sander H Diks, Carina L Bos, Vinay Nagaraj, Corné M J Pieterse, Thomas Boller, Andres Wiemken, Maikel P Peppelenbosch
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6605 (2009)
External sugar initiates biosynthesis of the reserve carbohydrate fructan, but the molecular processes mediating this response remain obscure. Previously it was shown that a phosphatase and a general kinase inhibitor hamper fructan accumulation. We u
Externí odkaz:
https://doaj.org/article/48776519bc15441c8d82a87898c150b6
Autor:
Daniel W. Hommes, Pim J. Koelink, Maikel P. Peppelenbosch, Dick J. Richel, Eva Hoff, Jarom Heijmans, Hein W. Verspaget, Ashwin A. Dihal, Philip W. Voorneveld, Gijs R. van den Brink, James C. H. Hardwick, Vanesa Muncan, Manon E. Wildenberg, Carina L. Bos, Bart Baan
Publikováno v:
Gut, 61(12), 1708-1715
Baan, B, Dihal, A A, Hoff, E, Bos, C L, Voorneveld, P W, Koelink, P J, Wildenberg, M E, Muncan, V, Heijmans, J, Verspaget, H W, Richel, D J, Hardwick, J C H, Hommes, D W, Peppelenbosch, M P & van den Brink, G R 2012, ' 5-aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer ', Gut, vol. 61, no. 12, pp. 1708-1715 . https://doi.org/10.1136/gutjnl-2011-301626
Gut, 61(12), 1708-1715. BMJ Publishing Group
Baan, B, Dihal, A A, Hoff, E, Bos, C L, Voorneveld, P W, Koelink, P J, Wildenberg, M E, Muncan, V, Heijmans, J, Verspaget, H W, Richel, D J, Hardwick, J C H, Hommes, D W, Peppelenbosch, M P & van den Brink, G R 2012, ' 5-aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer ', Gut, vol. 61, no. 12, pp. 1708-1715 . https://doi.org/10.1136/gutjnl-2011-301626
Gut, 61(12), 1708-1715. BMJ Publishing Group
Background 5-aminosalicylic acid (5-ASA) may protect against the development of inflammation-associated colorectal cancer. In vitro data suggest that, in colorectal cancer cells, 5-ASA induces cell cycle arrest, but the molecular mechanism leading to
Autor:
M. M. van Santen, Dirk J. Richel, James C. H. Hardwick, G. R. van den Brink, Maikel P. Peppelenbosch, Carina L. Bos, L. L. Kodach, Sander H. Diks
Publikováno v:
Oncogene, 25(49), 6447-6456. Nature Publishing Group
ONCOGENE, 25(49), 6447-6456. Nature Publishing Group
ONCOGENE, 25(49), 6447-6456. Nature Publishing Group
Nonsteroidal anti-inflammatory drugs show chemopreventive efficacy in colon cancer, but the mechanism behind this remains unclear. Elucidating this mechanism is seen as vital to the development of new chemopreventive agents. We studied the effects of
Autor:
Carmen Veríssima Ferreira, Carina L. Bos, Maikel P. Peppelenbosch, Liudmila L. Kodach, James C. H. Hardwick, Nelson Durán
Publikováno v:
Carcinogenesis, 27(3), 508-516. Oxford University Press
CARCINOGENESIS, 27(3), 508-516. Oxford University Press
CARCINOGENESIS, 27(3), 508-516. Oxford University Press
Despite recent additions to the armory of chemotherapeutic agents for colorectal cancer (CRC) treatment, the results of chemotherapy remain unsatisfactory. 5-Fluorouracil (5-FU) still represents the cornerstone of treatment and resistance to its acti
Autor:
Sander H. Diks, Cristiane Fernandes de Assis, Carina L. Bos, Carmen Verissima Ferreira, Alexandre Donizeti Martins Cavagis, Hiroshi Aoyama, Maikel P. Peppelenbosch, Henri H. Versteeg, Sylvia A. Bleuming
Publikováno v:
Experimental Hematology, 34(2), 188-196. ELSEVIER SCIENCE INC
Experimental hematology, 34(2), 188-196. Elsevier Inc.
Experimental hematology, 34(2), 188-196. Elsevier Inc.
Objective. Tetrahydroxyquinone is a molecule best known as a primitive anticataract drug but is also a highly redox active molecule that can take part in a redox cycle with semiquinone radicals, leading to the formation of reactive oxygen species (RO
Publikováno v:
international journal of biochemistry & cell biology. 36(7):1187-1205
Prostanoids are arachidonic acid metabolites and are generally accepted to play pivotal functions in amongst others inflammation, platelet aggregation, and vasoconstriction/relaxation. Inhibition of their production with, for instance, aspirin has be
Autor:
Maikel P. Peppelenbosch, Nelson Durán, Giselle Z. Justo, Carmen Veríssima Ferreira, Carina L. Bos, Henri H. Versteeg
Publikováno v:
Blood, 104(5), 1459-1464. American Society of Hematology
Violacein, a pigment isolated from Chromobacterium violaceum in the Amazon River, presents diverse biologic properties and attracts interest as a consequence of its antileukemic activity. Elucidation of the molecular mechanism mediating this activity
Publikováno v:
Molecular medicine (Cambridge, Mass.), 8(12), 857-862. Feinstein Institute for Medical Research
Background: Farnesyl protein transferase inhibitors have emerged as promising novel agents for combating cancerous disease. Nevertheless, the importance for farnesyl protein transferase enzymatic activity for cellular physiology of untransformed cell
Autor:
Carina L. Bos, Vinay J. Nagaraj, David Brodmann, Andres Wiemken, Thomas Boller, Tita Ritsema, Maikel P. Peppelenbosch, Sander H. Diks, Corné M. J. Pieterse
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6605 (2009)
PLoS ONE, 4(8), e6605. PLoS ONE
PLoS ONE, 4(8):e6605. PUBLIC LIBRARY SCIENCE
PLoS ONE, 4(8), e6605. PLoS ONE
PLoS ONE, 4(8):e6605. PUBLIC LIBRARY SCIENCE
External sugar initiates biosynthesis of the reserve carbohydrate fructan, but the molecular processes mediating this response remain obscure. Previously it was shown that a phosphatase and a general kinase inhibitor hamper fructan accumulation. We u
Autor:
Carina L. Bos, Lisa G. M. van Baarsen, Cornelis L. Verweij, Tineke C. T. M. van der Pouw Kraan
Publikováno v:
Arthritis Research & Therapy
van Baarsen, L G M, Bos, C L, van der Pouw Kraan, T & Verweij, C L 2009, ' Transcription profiling of rheumatic diseases ', Arthritis Research & Therapy, vol. 11, no. 1, 207 . https://doi.org/10.1186/ar2557
Arthritis Research & Therapy, 11(1):207. BioMed Central
van Baarsen, L G M, Bos, C L, van der Pouw Kraan, T & Verweij, C L 2009, ' Transcription profiling of rheumatic diseases ', Arthritis Research & Therapy, vol. 11, no. 1, 207 . https://doi.org/10.1186/ar2557
Arthritis Research & Therapy, 11(1):207. BioMed Central
Rheumatic diseases are a diverse group of disorders. Most of these diseases are heterogeneous in nature and show varying responsiveness to treatment. Because our understanding of the molecular complexity of rheumatic diseases is incomplete and criter