Vps39 Interacts with Tom40 to Establish One of Two Functionally Distinct Vacuole-Mitochondria Contact Sites

Autor: Florian Fröhlich, Martin van der Laan, Christian Ungermann, Thomas Becker, Carina Hönscher, Fulvio Reggiori, Kathrin Auffarth, Ayelén González Montoro, Bettina Warscheid, Maria Bohnert

Publikováno v: Developmental Cell
Developmental Cell, 45(5), 621-636.e7. CELL PRESS
González Montoro, A, Auffarth, K, Hönscher, C, Bohnert, M, Becker, T, Warscheid, B, Reggiori, F, van der Laan, M, Fröhlich, F & Ungermann, C 2018, ' Vps39 Interacts with Tom40 to Establish One of Two Functionally Distinct Vacuole-Mitochondria Contact Sites ', Developmental Cell, vol. 45, no. 5, pp. 621-636.e7 . https://doi.org/10.1016/j.devcel.2018.05.011

The extensive subcellular network of membrane contact sites plays central roles in organelle biogenesis and communication, yet the precise contributions of the involved machineries remain largely enigmatic. The yeast vacuole forms a membrane contact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b4e1d3bd43918d885926515c7332b9
https://pubmed.ncbi.nlm.nih.gov/29870720

A close-up view of membrane contact sites between the endoplasmic reticulum and the endolysosomal system: from yeast to man

Autor: Carina Hönscher, Christian Ungermann

Publikováno v: Critical reviews in biochemistry and molecular biology. 49(3)

Maintenance of organelle identity is crucial for the functionality of eukaryotic cells. Hence, transfer reactions between different compartments must be highly efficient and tightly regulated at the same time. Membrane contact sites (MCSs) represent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e00a673552ab2afb15ffc645cdf6b3
https://pubmed.ncbi.nlm.nih.gov/24382115

Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex

Autor: Anne Kuhlee, Siegfried Engelbrecht-Vandré, Christos Gatsogiannis, Henning J. kleine Balderhaar, Carina Hönscher, Christian Ungermann, Cornelia Bröcker, Stefan Raunser

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 109(6)

Membrane fusion within the eukaryotic endomembrane system depends on the initial recognition of Rab GTPase on transport vesicles by multisubunit tethering complexes and subsequent coupling to SNARE-mediated fusion. The conserved vacuolar/lysosomal ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005c22ed2ed14366cd37b65c83574890
https://pubmed.ncbi.nlm.nih.gov/22308417