Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carin Thomas"'
Publikováno v:
Journal of Chemical Education. 92:788-796
In the Community-Based Inquiry (CBI) instructional method, cooperative student groups complete case study activities based on scientific literature and conduct their own laboratory investigations that address authentic community needs. This study com
Autor:
Stephanie Bryner, Justin Johnston, Celia Faiola, Annika Nieber, Sara Rybka, Anne M. Johansen, Mark H. Engelhard, Carin Thomas, Kalyn S. Owens, Ponnusamy Nachimuthu
Publikováno v:
Aerosol Science and Technology. 45:1109-1122
The ultrafine size fraction of ambient particles (ultrafine particles [UFP], diameter < 100 nm) has been identified as being particularly potent in their adverse health effects, yet, the detailed mechanisms for why UFP display such distinctive toxici
Publikováno v:
Biochemical Pharmacology. 61:595-603
1,2-Dibromoethane (DBE) is an environmental contaminant that is metabolized by glutathione S-transferases to a haloethane–glutathione conjugate. Since haloethane–glutathione conjugates are known to alkylate nuclear DNA and cytoplasmic proteins, t
Publikováno v:
Free Radical Research. 21:387-397
Creatine kinase is a sulfhydryl containing enzyme that is particularly susceptible to oxidative inactivation. This enzyme is potentially vulnerable to inactivation under conditions when it would be used as a diagnostic marker of tissue damage such as
Publikováno v:
Biochemical Pharmacology. 45:1967-1972
d -1,2-Bis(3,5-dioxopiperazine-1-yl)propane (ICRF-187) (ADR-529) is a drug that ameliorates the cardiotoxicity of Adriamycin®. The drug enters cells where hydrolysis leads to its diacid diamide product, dl - N , N ′-dicarboxamidomethyl- N , N ′-
Publikováno v:
Biochemical Pharmacology. 44:1603-1608
A structure-activity study of fourteen chemically related flavonoids was conducted to evaluate their abilities to inhibit glutathione reductase (GR). By comparing the I 50 values of flavonoids from different classes possessing an identical hydroxyl c
Publikováno v:
Photochemistry and Photobiology. 55:47-53
— Photosensitized inhibition of mitochondrial succinoxidase by hypericin was measured in vitro and found to be drug-dose, light-dose, and wavelength dependent. Singlet oxygen generation, monitored using the singlet oxygen trap tetramethylethylene,
Publikováno v:
Redox report : communications in free radical research. 14(3)
Mitochondrial dysfunction and reactive oxygen species (ROS) are often implicated in diseases involving oxidative stress and elevated iron. As mitochondria produce ATP by oxidative phosphorylation, ROS by-products are generated from the electron trans
Publikováno v:
Free Radical Biology and Medicine. 76:S118
Autor:
Margret C. M. Vissers, Carin Thomas
Publikováno v:
Free radical biologymedicine. 23(3)
We have investigated whether the cell adhesion-promoting properties of the subendothelial matrix are affected by exposure to neutrophil-derived oxidants. Native subendothelial matrix was exposed to increasing doses of H2O2 in the presence of myeloper