Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Carin I. M. Dahlberg"'
1
Akademický článek
Assessment of T Cell Receptor Complex Expression Kinetics in Natural Killer Cells
Autor: Khder H. Rasul, Alamdar Hussain, Hazel Reilly, Maria Karvouni, Carin I. M. Dahlberg, Mustafa S. Al-Attar, Arnika K. Wagner, Evren Alici, Dara K. Mohammad
Publikováno v: Current Issues in Molecular Biology, Vol 44, Iss 9, Pp 3859-3871 (2022)
Among the polypeptides that comprise the T cell receptor (TCR), only CD3ζ is found in Natural Killer (NK) cells, where it transmits signals from activating receptors such as CD16 and NKp46. NK cells are potent immune cells that recognize target cell
Externí odkaz: https://doaj.org/article/7bfca1222273450aa573a8f6db2a9a01
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2
Akademický článek
Deletion of Wiskott–Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
Autor: Marisa A. P. Baptista, Marton Keszei, Mariana Oliveira, Karen K. S. Sunahara, John Andersson, Carin I. M. Dahlberg, Austen J. Worth, Agne Liedén, I-Chun Kuo, Robert P. A. Wallin, Scott B. Snapper, Liv Eidsmo, Annika Scheynius, Mikael C. I. Karlsson, Gerben Bouma, Siobhan O. Burns, Mattias N. E. Forsell, Adrian J. Thrasher, Susanne Nylén, Lisa S. Westerberg
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Wiskott–Aldrich syndrome (WAS) is a severe X-linked primary immunodeficiency syndrome. Here, the authors show that loss of WAS gene in dendritic cells results in increased activity of Rac2, increase of phagosomal pH, and more efficient cross-presen
Externí odkaz: https://doaj.org/article/b30cb5531b534a4c9f3e0c5bebf69da8
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3
Akademický článek
The Small Rho GTPases Rac1 and Rac2 Are Important for T-Cell Independent Antigen Responses and for Suppressing Switching to IgG2b in Mice
Autor: Natalija Gerasimčik, Minghui He, Carin I. M. Dahlberg, Nikolai V. Kuznetsov, Eva Severinson, Lisa S. Westerberg
Publikováno v: Frontiers in Immunology, Vol 8 (2017)
The Rho GTPases Cdc42, Rac1, and Rac2 coordinate receptor signaling to cell adhesion, migration, and proliferation. Deletion of Rac1 and Rac2 early during B cell development leads to failure in B cell entry into the splenic white pulp. Here, we sough
Externí odkaz: https://doaj.org/article/e33076fef44b4b5c82948d2d89d2d338
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4
Functional assessment for clinical use of serum-free adapted NK-92 cells
Autor: Evren Alici, Vladimir Beljanski, Birgitta Stellan, Michael Chrobok, Carin I. M. Dahlberg, Adil Doganay Duru, Ece Canan Sayitoglu, Hareth Nahi, Tolga Sutlu, Mari Gilljam
Publikováno v: Cancers
Volume 11
Issue 1
Cancers, Vol 11, Iss 1, p 69 (2019)
Natural killer (NK) cells stand out as promising candidates for cellular immunotherapy due to their capacity to kill malignant cells. However, the therapeutic use of NK cells is often dependent on cell expansion and activation with considerable amoun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ad2fe3023561f5855f226c417414aa
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6
Deletion of WASp and N-WASp in B cells cripples the germinal center response and results in production of IgM autoantibodies
Autor: Stefano Volpi, Carin I. M. Dahlberg, Luigi D. Notarangelo, Jolan E. Walter, Scott B. Snapper, Magda-Liz Torres, Mikael C. I. Karlsson, Lisa S. Westerberg, Sven H. Petersen, Marisa A. P. Baptista, Emilie K. Grasset, Marton Keszei
Publikováno v: Journal of Autoimmunity. 62:81-92
Humoral immunodeficiency caused by mutations in the Wiskott-Aldrich syndrome protein (WASp) is associated with failure to respond to common pathogens and high frequency of autoimmunity. Here we addressed the question how deficiency in WASp and the ho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46ab66b1839923a5e3f68b8e2a40262
https://doi.org/10.1016/j.jaut.2015.06.003
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7
The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells
Autor: Michel J. Massaad, Raif S. Geha, Carin I. M. Dahlberg, Eva Severinson, Natalija Gerasimcik, Lisa S. Westerberg, Marisa A. P. Baptista
Publikováno v: The Journal of Immunology. 194:4750-4758
The Rho GTPase Cdc42 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the Wiskott–Aldrich syndrome protein. We sought to define the role of intrinsic expression of Cdc42 by mature B cells in their activ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883592f5fe3747c0f7c3808ab967c06a
https://doi.org/10.4049/jimmunol.1401634
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9
IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo
Autor: John Andersson, Jordan S. Orange, Carin I. M. Dahlberg, Lisa S. Westerberg, Marisa A. P. Baptista, Joanna S. Kritikou, Sudeepta Kumar Panda, Cecilia Poli, Hanna Brauner, Lavesh A. Gwalani, Klas Kärre, Fredrik Wermeling, Susan M. Kaech, Arnika Kathleen Wagner, Pinaki P. Banerjee
Publikováno v: Scientific Reports
To kill target cells, natural killer (NK) cells organize signaling from activating and inhibitory receptors to form a lytic synapse. Wiskott-Aldrich syndrome (WAS) patients have loss-of-function mutations in the actin regulator WASp and suffer from i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d439a98a365c8dfdc291a3be207227
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