Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Carin E.G Havenith"'
Autor:
John A. Hartley, Patrick H. van Berkel, Philip W. Howard, David G. Williams, Paul W.H.I. Parren, Teresa Marafioti, Francois D'Hooge, Conor Barry, Luke A. Masterson, Arnaud Tiberghien, Jean-Noel Levy, Carin E.G. Havenith, Charles E. Britten, Narinder Janghra, Ayse U. Akarca, Peter C. Tyrer, Francesca Zammarchi, Michael J. Flynn
MTS assays on cell lines after treatment with ADCT-301, Non-binding ADC and naked antibody, HuMax-TAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cab9c15f4c9a2e0ecf693cb26650fa5
https://doi.org/10.1158/1535-7163.22506658.v1
https://doi.org/10.1158/1535-7163.22506658.v1
Autor:
John A. Hartley, Patrick H. van Berkel, Philip W. Howard, David G. Williams, Paul W.H.I. Parren, Teresa Marafioti, Francois D'Hooge, Conor Barry, Luke A. Masterson, Arnaud Tiberghien, Jean-Noel Levy, Carin E.G. Havenith, Charles E. Britten, Narinder Janghra, Ayse U. Akarca, Peter C. Tyrer, Francesca Zammarchi, Michael J. Flynn
Despite the many advances in the treatment of hematologic malignancies over the past decade, outcomes in refractory lymphomas remain poor. One potential strategy in this patient population is the specific targeting of IL2R-α (CD25), which is overexp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94d87c9eaa1b67f3d27abdb314cb187b
https://doi.org/10.1158/1535-7163.c.6538456.v1
https://doi.org/10.1158/1535-7163.c.6538456.v1
Autor:
Patrick H. van Berkel, Ronald Herbst, David A. Tice, Steve Coats, John A. Hartley, Philip W. Howard, Neil H. Bander, Sae Kim, He Liu, Eva Corey, Simon Chivers, Mary Jane Masson Hinrichs, Martin Korade, Patrick Strout, Kevin Schifferli, Ravinder Tammali, Karma Dacosta, Wanda King, Charles E. Britten, Sandamali Dissanayake, Halla W. Reinert, Lauren Adams, Simon Corbett, Francois Bertelli, Nazzareno Dimasi, Kapil Vashisht, Ryan Fleming, Francois D'Hooge, Peter Tyrer, Noel R. Monks, Carin E.G. Havenith, David G. Williams, Francesca Zammarchi, Song Cho
Supplementary Figure S1. Retention of MEDI3726 activity in human, cynomolgus monkey plasma or PBS for up to 7 days. Supplementary Figure S2. Kaplan-Meier analysis of the Time-to-Endpoint Survival in the (A) LNCaP, (B) CWR22Rv1, and (C) PC-3 Xenograft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fba3333e7f01b57533060b9dc76a71f
https://doi.org/10.1158/1535-7163.22505436.v1
https://doi.org/10.1158/1535-7163.22505436.v1
Autor:
John A. Hartley, Patrick H. van Berkel, Philip W. Howard, David G. Williams, Paul W.H.I. Parren, Teresa Marafioti, Francois D'Hooge, Conor Barry, Luke A. Masterson, Arnaud Tiberghien, Jean-Noel Levy, Carin E.G. Havenith, Charles E. Britten, Narinder Janghra, Ayse U. Akarca, Peter C. Tyrer, Francesca Zammarchi, Michael J. Flynn
In vivo efficacy in Karpas disseminated models. Kaplan Meier survival plots of disseminated Karpas 299 models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d89da2396830a9cd4a1808fac4ffc2
https://doi.org/10.1158/1535-7163.22506649
https://doi.org/10.1158/1535-7163.22506649
Autor:
John A. Hartley, Patrick H. van Berkel, Philip W. Howard, David G. Williams, Paul W.H.I. Parren, Teresa Marafioti, Francois D'Hooge, Conor Barry, Luke A. Masterson, Arnaud Tiberghien, Jean-Noel Levy, Carin E.G. Havenith, Charles E. Britten, Narinder Janghra, Ayse U. Akarca, Peter C. Tyrer, Francesca Zammarchi, Michael J. Flynn
Comet assay on CD25-negative Daudi cells after ADCT-301 and SG3199 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084a5316ee1f2b89055edf21f1791e74
https://doi.org/10.1158/1535-7163.22506655.v1
https://doi.org/10.1158/1535-7163.22506655.v1
Autor:
Patrick H. van Berkel, Ronald Herbst, David A. Tice, Steve Coats, John A. Hartley, Philip W. Howard, Neil H. Bander, Sae Kim, He Liu, Eva Corey, Simon Chivers, Mary Jane Masson Hinrichs, Martin Korade, Patrick Strout, Kevin Schifferli, Ravinder Tammali, Karma Dacosta, Wanda King, Charles E. Britten, Sandamali Dissanayake, Halla W. Reinert, Lauren Adams, Simon Corbett, Francois Bertelli, Nazzareno Dimasi, Kapil Vashisht, Ryan Fleming, Francois D'Hooge, Peter Tyrer, Noel R. Monks, Carin E.G. Havenith, David G. Williams, Francesca Zammarchi, Song Cho
Table S1. P values of comparing time to endpoint survival among all treatment groups in the LNCaP xenograft study Table S2. Summary of PSMA IHC in xenograft tumors Table S3. P values of comparing time to endpoint survival among all treatment groups i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231399c1a6b9388e7ff58e433d77c143
https://doi.org/10.1158/1535-7163.22505430
https://doi.org/10.1158/1535-7163.22505430
Autor:
John A. Hartley, Patrick H. van Berkel, Philip W. Howard, David G. Williams, Paul W.H.I. Parren, Teresa Marafioti, Francois D'Hooge, Conor Barry, Luke A. Masterson, Arnaud Tiberghien, Jean-Noel Levy, Carin E.G. Havenith, Charles E. Britten, Narinder Janghra, Ayse U. Akarca, Peter C. Tyrer, Francesca Zammarchi, Michael J. Flynn
In vivo PBMC DNA cross-linking. DNA cross-linking as measured in CD25-negative PBMCs from SCID mice treated with ADCT-301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d07833473f6a011f27559caa1dbb718
https://doi.org/10.1158/1535-7163.22506643.v1
https://doi.org/10.1158/1535-7163.22506643.v1
Autor:
John A. Hartley, Patrick H. van Berkel, Philip W. Howard, David G. Williams, Paul W.H.I. Parren, Teresa Marafioti, Francois D'Hooge, Conor Barry, Luke A. Masterson, Arnaud Tiberghien, Jean-Noel Levy, Carin E.G. Havenith, Charles E. Britten, Narinder Janghra, Ayse U. Akarca, Peter C. Tyrer, Francesca Zammarchi, Michael J. Flynn
DAR determination by SEC, RPLC and HIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5077bacf71462b389ff5e27cee130bfb
https://doi.org/10.1158/1535-7163.22506661
https://doi.org/10.1158/1535-7163.22506661
Autor:
Patrick H. van Berkel, Ronald Herbst, David A. Tice, Steve Coats, John A. Hartley, Philip W. Howard, Neil H. Bander, Sae Kim, He Liu, Eva Corey, Simon Chivers, Mary Jane Masson Hinrichs, Martin Korade, Patrick Strout, Kevin Schifferli, Ravinder Tammali, Karma Dacosta, Wanda King, Charles E. Britten, Sandamali Dissanayake, Halla W. Reinert, Lauren Adams, Simon Corbett, Francois Bertelli, Nazzareno Dimasi, Kapil Vashisht, Ryan Fleming, Francois D'Hooge, Peter Tyrer, Noel R. Monks, Carin E.G. Havenith, David G. Williams, Francesca Zammarchi, Song Cho
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4924695dc910a4941d12258d7652e0
https://doi.org/10.1158/1535-7163.22505433.v1
https://doi.org/10.1158/1535-7163.22505433.v1
Autor:
Patrick H. van Berkel, Ronald Herbst, David A. Tice, Steve Coats, John A. Hartley, Philip W. Howard, Neil H. Bander, Sae Kim, He Liu, Eva Corey, Simon Chivers, Mary Jane Masson Hinrichs, Martin Korade, Patrick Strout, Kevin Schifferli, Ravinder Tammali, Karma Dacosta, Wanda King, Charles E. Britten, Sandamali Dissanayake, Halla W. Reinert, Lauren Adams, Simon Corbett, Francois Bertelli, Nazzareno Dimasi, Kapil Vashisht, Ryan Fleming, Francois D'Hooge, Peter Tyrer, Noel R. Monks, Carin E.G. Havenith, David G. Williams, Francesca Zammarchi, Song Cho
Prostate-specific membrane antigen (PSMA) is a membrane-bound glutamate carboxypeptidase that is highly expressed in nearly all prostate cancers with the highest expression in metastatic castration-resistant prostate cancer (mCRPC). The prevalence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::321b0f7676a6116fbc4184f047275750
https://doi.org/10.1158/1535-7163.c.6538059.v1
https://doi.org/10.1158/1535-7163.c.6538059.v1