Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carin Christou"'
Autor:
Carmen M Wong, Kathy L Poulin, Grace Tong, Carin Christou, Michael A Kennedy, Theresa Falls, John C Bell, Robin J Parks
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151516 (2016)
Adenoviruses (Ads) are used in numerous preclinical and clinical studies for delivery of anti-cancer therapeutic genes. Unfortunately, Ad has a poor ability to distribute throughout a tumor mass after intratumoral injection, and infects cells primari
Externí odkaz:
https://doaj.org/article/825e776ffce4444e9cbb53baa38f6026
Autor:
Andrea N. Giberson, Bratati Saha, Kalisa Campbell, Robin J. Parks, Carin Christou, Kathy L. Poulin
Publikováno v:
Biochemistry and Cell Biology. 96:797-807
Adenovirus (Ad) DNA undergoes dynamic changes in protein association as the virus progresses through its replicative cycle. Within the virion, the Ad DNA associates primarily with the virus-encoded, protamine-like protein VII. During the early phase
Autor:
Kathy L. Poulin, John C. Bell, Grace Tong, Carmen M. Wong, Theresa Falls, Robin J. Parks, Michael A. Kennedy, Carin Christou
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151516 (2016)
PLoS ONE
PLoS ONE
Adenoviruses (Ads) are used in numerous preclinical and clinical studies for delivery of anti-cancer therapeutic genes. Unfortunately, Ad has a poor ability to distribute throughout a tumor mass after intratumoral injection, and infects cells primari
Autor:
Robin J. Parks, Milagros Risco Quiroz, Michael A. Kennedy, Kathy L. Poulin, P. Joel Ross, Carin Christou
Publikováno v:
Journal of Virology. 85:3950-3958
Helper-dependent adenovirus (hdAd) vectors have shown tremendous potential in animal models of human disease in numerous preclinical studies. Expression of a therapeutic transgene can be maintained for several years after a single administration of t
Autor:
Carin Christou, Robin J. Parks
Publikováno v:
Human gene therapy. 22(4)
Many preclinical gene therapy studies use a reporter gene to evaluate vector design and performance in mouse models of human disease. Unfortunately, most commonly used reporter genes are immunogenic in mice, which confounds accurate evaluation of vec
Autor:
Carin Christou, Rashmi Kothary, Robin J. Parks, Milagros Risco Quiroz, Adam C. Smith, Robert M. Lanthier, Karen L. Powell, Ian A. J. Lorimer, Ryan W. O'Meara, Kathy L. Poulin
Publikováno v:
Journal of virology. 84(19)
Adenovirus (Ad) vectors are the most commonly used system for gene therapy applications, due in part to their ability to infect a wide array of cell types and tissues. However, many therapies would benefit from the ability to target the Ad vector onl
Autor:
Carin Christou, Robin J. Parks
Publikováno v:
Human Gene Therapy; Apr2011, Vol. 22 Issue 4, p499-506, 8p