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Akademický článek

ERBB2 (HER2) amplifications and co-occurring KRAS alterations in the circulating cell-free DNA of pancreatic ductal adenocarcinoma patients and response to HER2 inhibition

Autor: Afsaneh Barzi, Caroline M. Weipert, Carin R. Espenschied, Victoria M. Raymond, Andrea Wang-Gillam, Mohammad Amin Nezami, Eva J. Gordon, Daruka Mahadevan, Kabir Mody

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

PurposeDespite accumulating data regarding the genomic landscape of pancreatic ductal adenocarcinoma (PDAC), olaparib is the only biomarker-driven FDA-approved targeted therapy with a PDAC-specific approval. Treating ERBB2(HER2)-amplified PDAC with a

Externí odkaz: https://doaj.org/article/e7677069cab2423eb1241b17d63bdd06

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The Potential of Combining Thermal Scanning Probes and Phase-Change Materials for Tunable Metasurfaces

Autor: Michel, Ann-Katrin U., Meyer, Sebastian, Essing, Nicolas, Lassaline, Nolan, Lightner, Carin R., Bisig, Samuel, Norris, David J., Chigrin, Dmitry N.

Metasurfaces allow for the spatiotemporal variation of amplitude, phase, and polarization of optical wavefronts. Implementation of active tunability of metasurfaces promises compact flat optics capable of reconfigurable wavefront shaping. Phase-chang

Externí odkaz: http://arxiv.org/abs/2007.07938

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Akademický článek

Advancing Evidence Generation for Circulating Tumor DNA: Lessons Learned from A Multi-Assay Study of Baseline Circulating Tumor DNA Levels across Cancer Types and Stages

Publikováno v: Diagnostics, Vol 14, Iss 9, p 912 (2024)

Circulating tumor DNA (ctDNA) holds promise as a biomarker for predicting clinical responses to therapy in solid tumors, and multiple ctDNA assays are in development. However, the heterogeneity in ctDNA levels prior to treatment (baseline) across dif

Externí odkaz: https://doaj.org/article/6100185e977649be90845d41c4acd4d9

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