Výsledky vyhledávání - "Carias, Heidi"

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

Autor: Cromm, Philipp M., Crews, Craig M., Mainolfi, Nello, Rasmusson, Tim, Poulikakos, Poulikos I., Zhang, Chao, Bollag, Gideon, Shokat, Kevan M., Rosen, Neal, Agianian, Bogos, Gavathiotis, Evripidis, Raina, Kanak, Durrant, David E., Morrison, Deborah K., Neklesa, Taavi K., Winkler, James D., Chang, F., Steelman, L. S., Lee, J. T., Shelton, J. G., Navolanic, P. M., Blalock, W. L., Franklin, R. A., McCubrey, J. A., Burslem, George M., Smith, Blake E., Lai, Ashton C., Jaime-Figueroa, Saul, McQuaid, Daniel C., Bondeson, Daniel P., Toure, Momar, Dong, Hanqing, Qian, Yimin, Wang, Jing, Crew, Andrew P., Hines, John, Sanchez, Jaquelyn N., Wang, Ton, Cohen, Mark S., Shelledy, PharmD, Lindsay, Roman, PharmD, BCOP, Danielle, Davies, Helen, Bignell, Graham R., Cox, Charles, Stephens, Philip, Edkins, Sarah, Clegg, Sheila, Teague, Jon, Woffendin, Hayley, Garnett, Mathew J., Bottomley, William, Davis, Neil, Dicks, Ed, Ewing, Rebecca, Floyd, Yvonne, Gray, Kristian, Hall, Sarah, Hawes, Rachel, Hughes, Jaime, Kosmidou, Vivian, Menzies, Andrew, Mould, Catherine, Parker, Adrian, Stevens, Claire, Watt, Stephen, Hooper, Steven, Jayatilake, Hiran, Gusterson, Barry A., Cooper, Colin, Shipley, Janet, Hargrave, Darren, Pritchard-Jones, Katherine, Maitland, Norman, Chenevix-Trench, Georgia, Riggins, Gregory J., Bigner, Darell D., Palmieri, Giuseppe, Cossu, Antonio, Flanagan, Adrienne, Nicholson, Andrew, Ho, Judy W.C., Leung, Suet Y., Yuen, Siu T., Weber, Barbara L., Seigler, Hilliard F., Darrow, Timothy L., Paterson, Hugh, Wooster, Richard, Stratton, Michael R., Futreal, P. Andrew, Spevak, Wayne, Zhang, Ying, Burton, Elizabeth A., Ma, Yan, Habets, Gaston, Zhang, Jiazhong, Lin, Jack, Ewing, Todd, Matusow, Bernice, Tsang, Garson, Marimuthu, Adhirai, Cho, Hanna, Wu, Guoxian, Wang, Weiru, Fong, Daniel, Nguyen, Hoa, Shi, Songyuan, Womack, Patrick, Nespi, Marika, Shellooe, Rafe, Carias, Heidi, Powell, Ben, Light, Emily, Sanftner, Laura, Walters, Jason, Tsai, James, West, Brian L., Visor, Gary, Rezaei, Hamid, Lin, Paul S., Nolop, Keith, Ibrahim, Prabha N., Hirth, Peter, Arozarena, Imanol, Wellbrock, Claudia, Samatar, Ahmed A., Karoulia, Zoi, Chapman, Paul B., Hauschild, Axel, Robert, Caroline, Haanen, John B., Ascierto, Paolo, Larkin, James, Dummer, Reinhard, Garbe, Claus, Testori, Alessandro, Maio, Michele, Hogg, David, Lorigan, Paul, Lebbe, Celeste, Jouary, Thomas, Schadendorf, Dirk, Ribas, Antoni, O'Day, Steven J., Sosman, Jeffrey A., Kirkwood, John M., Eggermont, Alexander M.M., Dreno, Brigitte, Li, Jiang, Nelson, Betty, Hou, Jeannie, Lee, Richard J., Flaherty, Keith T., McArthur, Grant A., Vogelstein, Bert, Papadopoulos, Nickolas, Velculescu, Victor E., Zhou, Shibin, Diaz, Luis A., Kinzler, Kenneth W., Millington, G. W.M., Buhimschi, Alexandru D., Hamman, Brian D., Ishchenko, Alexey

Publikováno v: Cromm, P M, Crews, C M, Mainolfi, N, Rasmusson, T, Poulikakos, P I, Zhang, C, Bollag, G, Shokat, K M, Rosen, N, Crews, C M, Agianian, B, Gavathiotis, E, Raina, K, Crews, C M, Durrant, D E, Morrison, D K, Neklesa, T K, Winkler, J D, Crews, C M, Chang, F, Steelman, L S, Lee, J T, Shelton, J G, Navolanic, P M, Blalock, W L, Franklin, R A, McCubrey, J A, Burslem, G M, Smith, B E, Lai, A C, Jaime-Figueroa, S, McQuaid, D C, Bondeson, D P, Toure, M, Dong, H, Qian, Y, Wang, J, Crew, A P, Hines, J, Crews, C M, Sanchez, J N, Wang, T, Cohen, M S, Shelledy, PharmD, L, Roman, PharmD, BCOP, D, Davies, H, Bignell, G R, Cox, C, Stephens, P, Edkins, S, Clegg, S, Teague, J, Woffendin, H, Garnett, M J, Bottomley, W, Davis, N, Dicks, E, Ewing, R, Floyd, Y, Gray, K, Hall, S, Hawes, R, Hughes, J, Kosmidou, V, Menzies, A, Mould, C, Parker, A, Stevens, C, Watt, S, Hooper, S, Jayatilake, H, Gusterson, B A, Cooper, C, Shipley, J, Hargrave, D, Pritchard-Jones, K, Maitland, N, Chenevix-Trench, G, Riggins, G J, Bigner, D D, Palmieri, G, Cossu, A, Flanagan, A, Nicholson, A, Ho, J W C, Leung, S Y, Yuen, S T, Weber, B L, Seigler, H F, Darrow, T L, Paterson, H, Wooster, R, Wooster, R, Stratton, M R, Futreal, P A, Zhang, C, Spevak, W, Zhang, Y, Burton, E A, Ma, Y, Habets, G, Zhang, J, Lin, J, Ewing, T, Matusow, B, Tsang, G, Marimuthu, A, Cho, H, Wu, G, Wang, W, Fong, D, Nguyen, H, Shi, S, Womack, P, Nespi, M, Shellooe, R, Carias, H, Powell, B, Light, E, Sanftner, L, Walters, J, Tsai, J, West, B L, Visor, G, Rezaei, H, Lin, P S, Nolop, K, Ibrahim, P N, Hirth, P, Bollag, G, Arozarena, I, Wellbrock, C, Samatar, A A, Poulikakos, P I, Karoulia, Z, Gavathiotis, E, Poulikakos, P I, Chapman, P B, Hauschild, A, Robert, C, Haanen, J B, Ascierto, P, Larkin, J, Dummer, R, Garbe, C, Testori, A, Maio, M, Hogg, D, Lorigan, P, Lebbe, C, Jouary, T, Schadendorf, D, Ribas, A, O'Day, S J, Sosman, J A, Kirkwood, J M, Eggermont, A M M, Dreno, B, Nolop, K, Li, J, Nelson, B, Hou, J, Lee, R J, Flaherty, K T, McArthur, G A, Vogelstein, B, Papadopoulos, N, Velculescu, V E, Zhou, S, Diaz, L A, Kinzler, K W, Millington, G W M, Bondeson, D P, Smith, B E, Burslem, G M, Buhimschi, A D, Hines, J, Jaime-Figueroa, S, Wang, J, Hamman, B D, Ishchenko, A & Crews, C M 2018, ' The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study ', Cell Chemical Biology, pp. 67-77.e3 . https://doi.org/10.1016/j.chembiol.2017.09.009

Proteolysis targeting chimera (PROTAC) technology has emerged over the last two decades as a powerful tool for targeted degradation of endogenous proteins. Herein we describe the development of PROTACs for receptor tyrosine kinases, a protein family

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361df2b1e3e643d7e80d0d128cb88ce3
https://doi.org/10.1016/j.chembiol.2017.09.009

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