Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Carey L. Shive"'
Autor:
Shanmuga Sundaram Mahalingam, Sangeetha Jayaraman, Adhvika Arunkumar, Holly M. Dudley, Donald D. Anthony, Carey L. Shive, Jeffrey M. Jacobson, Pushpa Pandiyan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus Disease 2019 (COVID-19) that presents with varied clinical manifestations ranging from asymptomatic or mild infections and pneumonia to severe cases associated with cytok
Externí odkaz:
https://doaj.org/article/a75f7b50e5ed437bbec05ec3bbadc701
Autor:
Shahdi K. Malakooti, Hinnah Siddiqui, Brigid Wilson, Taissa Bej, Megan O’Mara, Alexandra Desotelle, Alyssa Lange, Carey L. Shive, Nora G. Singer, Grace A. McComsey, Lenche Kostadinova, Maya Mattar, David A. Zidar, Donald D. Anthony
Publikováno v:
Nutrients, Vol 16, Iss 3, p 401 (2024)
(1) Vitamin D deficiency is associated with mortality in the general population and has been observed in one rheumatoid arthritis (RA) cohort. Here, we investigate the relationship between 25-hydroxyvitamin D (25(OH)D) levels before methotrexate (MTX
Externí odkaz:
https://doaj.org/article/81fb9677ff374f52ae43262f7573d62f
Autor:
Carey L. Shive, Corinne M. Kowal, Alexandra F. Desotelle, Ynez Nguyen, Sarah Carbone, Lenche Kostadinova, Perica Davitkov, Megan O’Mara, Alexandra Reihs, Hinnah Siddiqui, Brigid M. Wilson, Donald D. Anthony
Publikováno v:
Cells, Vol 12, Iss 16, p 2034 (2023)
Both acute and chronic hepatitis C virus (HCV) infections are characterized by inflammation. HCV and reduced liver blood filtration contribute to inflammation; however, the mechanisms of systemic immune activation and dysfunction as a result of HCV i
Externí odkaz:
https://doaj.org/article/52ac9804b50e466a90a8fbc0b1026b0d
Autor:
Sofi Damjanovska, Hawwa Alao, Elizabeth Zebrowski, Corinne Kowal, Lenche Kostadinova, Perica Davitkov, Yngve Falck-Ytter, Carey L. Shive, Michael Cartwright, Brian Richardson, David Wald, Mark Cameron, Saba Valadkhan, Donald D. Anthony
Publikováno v:
Biology, Vol 11, Iss 9, p 1262 (2022)
Background: Hepatitis C virus (HCV) therapy lowers risk of hepatocellular carcinoma (HCC). Little is known about factors driving/preceding HCC in treated persons. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) regulate host response and pathog
Externí odkaz:
https://doaj.org/article/131cff5a4bf4481891dfcc198f640398
Autor:
Ann W.N. Auma, Carey L. Shive, Alyssa Lange, Sofi Damjanovska, Corinne Kowal, Elizabeth Zebrowski, Pushpa Pandiyan, Brigid Wilson, Robert C. Kalayjian, David H. Canaday, Donald D. Anthony
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe mechanisms underlying naïve CD4+ lymphopenia during chronic Hepatitis C Virus (HCV) infection are unclear. Whether direct-acting antiviral (DAA) therapy restores peripheral naïve CD4+ T cell numbers and function is unknown.MethodsWe e
Externí odkaz:
https://doaj.org/article/639e6fbfad364c11bc4487545f3d378e
Autor:
Carey L. Shive, Michael L. Freeman, Souheil-Antoine Younes, Corinne M. Kowal, David H. Canaday, Benigno Rodriguez, Michael M. Lederman, Donald D. Anthony
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Background: Immune non-responders (INR) are HIV+, ART-controlled (>2 yrs) people who fail to reconstitute their CD4 T cell numbers. Systemic inflammation and markers of T cell senescence and exhaustion are observed in INR. This study aims to investig
Externí odkaz:
https://doaj.org/article/877d6a41a162433c84481900387900cf
Autor:
Lenche Kostadinova, Carey L. Shive, Elizabeth Zebrowski, Brianna Fuller, Kelsey Rife, Amy Hirsch, Anita Compan, Anita Moreland, Yngve Falck-Ytter, Daniel L. Popkin, Donald D. Anthony
Publikováno v:
Pathogens and Immunity, Vol 3, Iss 1, Pp 149-163 (2018)
Background: During chronic hepatitis C virus (HCV) infection, Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) levels mark active liver inflammation and tissue damage, while albumin reflects synthetic liver function and nutritional
Externí odkaz:
https://doaj.org/article/a651cb373a704c528bb45bc7a62bed87
Publikováno v:
Viruses, Vol 14, Iss 1, p 50 (2021)
Chronic hepatitis C virus (HCV) infection is associated with naïve CD4+ T cell lymphopenia and long-standing/persistent elevation of cellular and soluble immune activation parameters, the latter heightened in the setting of HIV co-infection. The und
Externí odkaz:
https://doaj.org/article/4e24df0eed4844069d7d3dec8c706b6f
Autor:
Ann W N Auma, Corinne Kowal, Carey L Shive, Alyssa Lange, Sofi Damjanovska, Elizabeth Zebrowski, Elane Reyes, Leonard Calabrese, Lenche Kostadinova, Yngve Falck-Ytter, Maya Mattar, Donald D Anthony
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267512 (2022)
BackgroundElevated rheumatoid factor (RF) levels and systemic immune activation are highly prevalent during chronic hepatitis C virus (HCV) infection. Direct-acting antiviral (DAA) therapy has been associated with normalization of various soluble imm
Externí odkaz:
https://doaj.org/article/ce466ae99a50403cb903760ee2886fb4
Autor:
Nicholas T Funderburg, Carey L Shive, Zhengyi Chen, Curtis Tatsuoka, Emily R Bowman, Chris T Longenecker, Grace A McComsey, Brian M Clagett, Dominic Dorazio, Michael L Freeman, Scott F Sieg, Daniela Moisi, Donald D Anthony, Jeffrey M Jacobson, Sharon L Stein, Leonard H Calabrese, Alan Landay, Charles Flexner, Keith W Crawford, Edmund V Capparelli, Benigno Rodriguez, Michael M Lederman
Publikováno v:
Clinical Infectious Diseases.
Background People with human immunodeficiency virus (PWH) are at increased risk for comorbidities, and plasma interleukin 6 (IL-6) levels are among the most robust predictors of these outcomes. Tocilizumab (TCZ) blocks the receptor for IL-6, inhibiti