Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carey J, Fagerstrom"'
Autor:
Brian J. Galletta, Carey J. Fagerstrom, Todd A. Schoborg, Tiffany A. McLamarrah, John M. Ryniawec, Daniel W. Buster, Kevin C. Slep, Gregory C. Rogers, Nasser M. Rusan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The centrosome is a large intracellular structure that serves as the microtubule-organising center, but how it is accurately assembled is not known. Here the authors generate a ‘domain-level’ centrosome interactome and show that Plk4 positions th
Externí odkaz:
https://doaj.org/article/bd602ba043d3456eb55d85545a7af134
Autor:
Y Rose Citron, Carey J Fagerstrom, Bettina Keszthelyi, Bo Huang, Nasser M Rusan, Mark J S Kelly, David A Agard
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190530 (2018)
The centrosome serves as the main microtubule-organizing center in metazoan cells, yet despite its functional importance, little is known mechanistically about the structure and organizational principles that dictate protein organization in the centr
Externí odkaz:
https://doaj.org/article/694ab2598a494ff8bf281853da3c37b1
Autor:
Ramya Varadarajan, Brian J. Galletta, Carey J. Fagerstrom, Karen Plevock Haase, Nasser M. Rusan
Centrosomes are the major microtubule organizing centers (MTOC) of many cells and are composed of centrioles and the pericentriolar material (PCM). Centrosomes are an essential part of diverse cellular processes and require precise regulation of thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54793ed814672d457488c3f5a03592cf
https://doi.org/10.1101/2022.01.21.477277
https://doi.org/10.1101/2022.01.21.477277
Autor:
Matthew R. Hannaford, Rong Liu, Neil Billington, Zachary T. Swider, Brian J. Galletta, Carey J. Fagerstrom, Christian Combs, James R. Sellers, Nasser M. Rusan
Centrosome positioning is essential for their function. Typically, centrosomes are transported to various cellular locations through the interaction of centrosome nucleated microtubules with motor proteins. However, it remains unknown how centrioles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01421c8d034d8d0ecdb1d3f38e5816c8
https://doi.org/10.1101/2022.01.12.476023
https://doi.org/10.1101/2022.01.12.476023
Autor:
Matthew R, Hannaford, Rong, Liu, Neil, Billington, Zachary T, Swider, Brian J, Galletta, Carey J, Fagerstrom, Christian, Combs, James R, Sellers, Nasser M, Rusan
Publikováno v:
The Journal of cell biology. 221(9)
Centrosome positioning is essential for their function. Typically, centrosomes are transported to various cellular locations through the interaction of centrosomal microtubules (MTs) with motor proteins anchored at the cortex or the nuclear surface.
Autor:
Nasser M. Rusan, Gregory C. Rogers, Tiffany A. McLamarrah, Daniel W. Buster, Sarah K. Speed, Carey J. Fagerstrom, Brian J. Galletta
Centriole duplication begins with the assembly of a pre-procentriole at a single site on a mother centriole and proceeds with the hierarchical recruitment of a conserved set of proteins, including Polo-like kinase 4 (Plk4)/ZYG-1, Ana2/SAS-5/STIL, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9864e36ceb68752f1ad3c4b7503f597d
Publikováno v:
Molecular Biology of the Cell
Cell division is critical for development, organ growth, and tissue repair. The later stages of cell division include the formation of the microtubule (MT)-rich central spindle in anaphase, which is required to properly define the cell equator, guide
Publikováno v:
The Journal of Cell Biology
Loss of the centriole protein Asterless (Asl) prevents centriole duplication, which has limited the study of its function at centrioles. Here, Galletta et al. show that Asl controls centriole length and ensures proper basal body functions during sper
Publikováno v:
The Journal of Cell Biology
Calmodulin is required for abnormal spindle’s (Asp’s) ability to cross-link microtubules and ensure proper centrosome inheritance in neural stem cells, but it is dispensable for Asp’s role in brain size determination.
The interaction betwe
The interaction betwe
Autor:
Jacob M. Ortega, Justin M. Fear, Brian Oliver, Sharvani Mahadevaraju, Brian J. Galletta, Nasser M. Rusan, Samantha L. Smith, Carey J. Fagerstrom
Publikováno v:
Dev Cell
The centriole, or basal body, is the center of attachment between the sperm head and tail. While the distal end of the centriole templates the cilia, the proximal end associates with the nucleus. Using Drosophila, we identify a centriole-centric mech