Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Carey Backus"'
Autor:
Wei Qiu, Qi Sun, Yi Yang, Chirag Patel, Meng Sun, Yue Liu, Kyle Halliwill, Sarah Kim, Rebecca Mathew, Jennifer M Frost, Jennifer A Roth, Domenick Kennedy, Robert T Manguso, Kathleen B Yates, Hakimeh Ebrahimi-Nik, Christina K Baumgartner, Arvin Iracheta-Vellve, Keith M Hamel, Kira Olander, Thomas GR Davis, Kathleen A McGuire, Geoff T Halvorsen, Omar I Avila, Ashwin V Kammula, Audrey J Muscato, Prasanthi Geda, Kelly Klinge, Zhaoming Xiong, Ryan Duggan, Liang Mu, Mitchell D Yeary, James C Patti, Tyler M Balon, Carey Backus, Angeline Chen, Kenton Longenecker, Joseph Klahn, Cara Hrusch, Navasona Krishnan, Charles W Hutchins, Jacqueline Aguado, Marinka Bulic, Payal Tiwari, Kayla J Colvin, Cun Lan Chuong, Ian C Kohnle, Matthew G Rees, Andrew Boghossian, Melissa Ronan, Meng-Ju Wu, Debattama R Sen, Gabriel K Griffin, Nabeel El-Bardeesy, Patricia Trusk, Joshua H Decker, Stacey Fossey, Marcia N Paddock, Elliot P Farney, Clay Beauregard, Philip R Kym
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/11356ff1bf1f4b63ab1324cafa253315
Autor:
Ximena Paez-Colasante, Claudia Figueroa-Romero, Amy E. Rumora, Junguk Hur, Faye E. Mendelson, John M. Hayes, Carey Backus, Ghislaine F. Taubman, Laurie Heinicke, Nils G. Walter, Sami J. Barmada, Stacey A. Sakowski, Eva L. Feldman
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, and incurable neurodegenerative disease. Recent studies suggest that dysregulation of gene expression by microRNAs (miRNAs) may play an important role in ALS pathogenesis. The reversible na
Externí odkaz:
https://doaj.org/article/11f12ae882c444579525281c934fad4d
Autor:
Lucy M. Hinder, Phillipe D. O'Brien, John M. Hayes, Carey Backus, Andrew P. Solway, Catrina Sims-Robinson, Eva L. Feldman
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 6, Pp 717-725 (2017)
Patients with metabolic syndrome, which is defined as obesity, dyslipidemia, hypertension and impaired glucose tolerance (IGT), can develop the same macro- and microvascular complications as patients with type 2 diabetes, including peripheral neuropa
Externí odkaz:
https://doaj.org/article/407b69ee4b3248709c88a887471042a7
Autor:
Phillipe D. O'Brien, Lucy M. Hinder, Amy E. Rumora, John M. Hayes, Jacqueline R. Dauch, Carey Backus, Faye E. Mendelson, Eva L. Feldman
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 12 (2018)
Peripheral neuropathy (neuropathy) is a common complication of obesity and type 2 diabetes in children and adolescents. To model this complication in mice, 5-week-old male C57BL/6J mice were fed a high-fat diet to induce diet-induced obesity (DIO), a
Externí odkaz:
https://doaj.org/article/9b149fbcbee14aa4948c000a484b4045
Autor:
Phillipe D. O'Brien, Junguk Hur, John M. Hayes, Carey Backus, Stacey A. Sakowski, Eva L. Feldman
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 348-355 (2015)
Given the lack of treatments for diabetic neuropathy (DN), a common diabetic complication, accurate disease models are necessary. Characterization of the leptin-deficient BTBR ob/ob mouse, a type 2 diabetes model, demonstrated that the mice develop r
Externí odkaz:
https://doaj.org/article/cb593583f08240df9678cd7eaaa1e35c
Autor:
Colin K. Franz, Thais Federici, Jun Yang, Carey Backus, Sang Su Oh, Qingshan Teng, Erin Carlton, Kathie M. Bishop, Mehdi Gasmi, Raymond T. Bartus, Eva L. Feldman, Nicholas M. Boulis
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 3, Pp 473-481 (2009)
Background: Amyotrophic lateral sclerosis (ALS) is a devastating disease that is characterized by the progressive loss of motor neurons. Patients with ALS usually die from respiratory failure due to respiratory muscle paralysis. Consequently, therapi
Externí odkaz:
https://doaj.org/article/b08a536399554ec89b5daddd1dab6e3b
Autor:
Kelli A. Sullivan, John M. Hayes, Timothy D. Wiggin, Carey Backus, Sang Su Oh, Stephen I. Lentz, Frank Brosius, III, Eva L. Feldman
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 3, Pp 276-285 (2007)
Diabetic neuropathy (DN) is a debilitating complication of type 1 and type 2 diabetes. Rodent models of DN do not fully replicate the pathology observed in human patients. We examined DN in streptozotocin (STZ)-induced [B6] and spontaneous type 1 dia
Externí odkaz:
https://doaj.org/article/e226b4e0acac404d9de97b13a82cc4b6
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 1, Pp 11-22 (2006)
Dorsal root ganglia (DRG) neurons degenerate in diabetic neuropathy (DN) and exhibit mitochondrial damage. We studied mitochondria of cultured DRG neurons exposed to high glucose as an in vitro model of DN. High glucose sequentially increases the exp
Externí odkaz:
https://doaj.org/article/b054a9e5188a4744972c5ce98ab248b6
Autor:
Elizabeth M Gibbs, Ann E Davidson, Arden Trickey-Glassman, Carey Backus, Yu Hong, Stacey A Sakowski, James J Dowling, Eva L Feldman
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55888 (2013)
Dynamin-2 (DNM2) is a large GTPase involved in clathrin-mediated endocytosis and related trafficking pathways. Mutations in human DNM2 cause two distinct neuromuscular disorders: centronuclear myopathy and Charcot-Marie-Tooth disease. Zebrafish have
Externí odkaz:
https://doaj.org/article/57717add901946cd8241251f9e0fe59c
Autor:
Kathleen McGuire, Christina Baumgartner, Carey Backus, Rebecca Mathew, Kelly Klinge, Joseph Klahn, Prasanthi Geda, Kyle Halliwill, Jacqueline Aguado, Liang Mu, Ryan Duggan, Cara Hrusch, Elliot Farney, Zhaoming Xiong, Marinka Bulic, Patricia Trusk, Loren Lasko, Hakimeh Ebrahimi-Nik, Kathleen Yates, Robert Manguso, Keith Hamel, Marcia Paddock, Jennifer Frost, Philip Kym
Publikováno v:
Regular and Young Investigator Award Abstracts.