A Lassa virus live attenuated vaccine candidate that is safe and efficacious in guinea pigs.

Autor: Carey BD; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Yu S; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Geiger J; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Ye C; Department of Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, Texas, USA., Huzella LM; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Reeder RJ; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Mehta M; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Hirsch S; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Bernbaum R; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Cubitt B; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA., Pahar B; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Anthony SM; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Marketon A; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Bernbaum JG; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Tran JP; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., Crozier I; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Martínez-Sobrido L; Department of Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, Texas, USA., Worwa G; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA., de la Torre JC; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA. juanct@scripps.edu., Kuhn JH; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA. kuhnjens@mail.nih.gov.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2024 Nov 17; Vol. 9 (1), pp. 220. Date of Electronic Publication: 2024 Nov 17.

Comparison of transcriptional responses between pathogenic and nonpathogenic hantavirus infections in Syrian hamsters using NanoString.

Autor: Brocato RL; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America., Altamura LA; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America., Carey BD; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America., Perley CC; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America., Blancett CD; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America., Minogue TD; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America., Hooper JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Aug 02; Vol. 15 (8), pp. e0009592. Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021).

Protein Kinase C subtype δ interacts with Venezuelan equine encephalitis virus capsid protein and regulates viral RNA binding through modulation of capsid phosphorylation.

Autor: Carey BD; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Akhrymuk I; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Dahal B; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Pinkham CL; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Bracci N; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Finstuen-Magro S; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Lin SC; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Lehman CW; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America., Sokoloski KJ; Department of Microbiology and Immunology, and the Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville School of Medicine, Louisville, Kentucky, United States of America., Kehn-Hall K; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2020 Mar 09; Vol. 16 (3), pp. e1008282. Date of Electronic Publication: 2020 Mar 09 (Print Publication: 2020).

EGR1 upregulation following Venezuelan equine encephalitis virus infection is regulated by ERK and PERK pathways contributing to cell death.

Autor: Dahal B; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA., Lin SC; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA., Carey BD; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA., Jacobs JL; QIAGEN Bioinformatics, Aarhus, Denmark; QIAGEN Bioinformatics, Maryland, USA., Dinman JD; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA., van Hoek ML; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA., Adams AA; Naval Research Laboratory, Washington, DC, USA., Kehn-Hall K; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA. Electronic address: kkehnhal@gmu.edu.

Publikováno v: Virology [Virology] 2020 Jan 02; Vol. 539, pp. 121-128. Date of Electronic Publication: 2019 Oct 31.

Venezuelan Equine Encephalitis Virus Capsid Implicated in Infection-Induced Cell Cycle Delay in vitro .

Autor: Lundberg L; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, United States., Fontenot J; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, United States., Lin SC; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, United States., Pinkham C; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, United States., Carey BD; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, United States., Campbell CE; DCE Consulting, Vienna, VA, United States., Kehn-Hall K; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, United States.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2018 Dec 18; Vol. 9, pp. 3126. Date of Electronic Publication: 2018 Dec 18 (Print Publication: 2018).