Patient-derived granulocyte/macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates.

Autor: Sakagami T, Beck D, Uchida K, Suzuki T, Carey BC, Nakata K, Keller G, Wood RE, Wert SE, Ikegami M, Whitsett JA, Luisetti M, Davies S, Krischer JP, Brody A, Ryckman F, Trapnell BC, Sakagami, Takuro, Beck, David, Uchida, Kanji

Publikováno v: American Journal of Respiratory & Critical Care Medicine; 7/1/2010, Vol. 182 Issue 1, p49-61, 13p

Review: early statin therapy does not reduce the composite endpoint of death, MI, or stroke in acute coronary syndromes.

Autor: Carey BC, Berger PB

Publikováno v: ACP Journal Club; Nov/Dec2006, Vol. 145 Issue 3, p61-61, 1p

A toxicology study of Csf2ra complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice.

Autor: Arumugam P; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA., Carey BC; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA., Wikenheiser-Brokamp KA; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA.; Division of Pathology & Laboratory Medicine, CCHMC, Cincinnati, OH, USA.; Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Krischer J; Departments of Pediatrics and Internal Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL, USA., Wessendarp M; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA., Shima K; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA., Chalk C; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA., Stock J; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA., Ma Y; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA., Black D; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA., Imbrogno M; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, UCMC, Cincinnati, OH, USA., Collins M; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, UCMC, Cincinnati, OH, USA., Kalenda Yombo DJ; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, UCMC, Cincinnati, OH, USA., Sakthivel H; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA., Suzuki T; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA., Lutzko C; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.; Cell Manipulations Laboratory, CCHMC, Cincinnati, OH, USA., Cancelas JA; Division of Experimental Hematology, CCHMC, Cincinnati, OH, USA., Adams M; Office for Clinical and Translational Research, CCHMC, Cincinnati, OH, USA., Hoskins E; Office for Clinical and Translational Research, CCHMC, Cincinnati, OH, USA., Lowe-Daniels D; Translational Core Laboratory, CCHMC, Cincinnati, OH, USA., Reeves L; Translational Core Laboratory, CCHMC, Cincinnati, OH, USA., Kaiser A; Office of Research Compliance & Regulatory Affairs, CCHMC, Cincinnati, OH, USA., Trapnell BC; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH, USA.; Division of Pulmonary Biology, Perinatal Institute, CCHMC, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, UCMC, Cincinnati, OH, USA.; Division of Pulmonary Medicine, CCHMC, Cincinnati, OH, USA.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2024 Feb 17; Vol. 32 (2), pp. 101213. Date of Electronic Publication: 2024 Feb 17 (Print Publication: 2024).

Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.

Autor: Hudock KM; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Collins MS; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Imbrogno MA; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Kramer EL; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Division of Pediatric Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Brewington JJ; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Division of Pediatric Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Ziady A; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Zhang N; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Snowball J; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Xu Y; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Divisions of Biomedical Informatics, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Carey BC; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Horio Y; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.; Department of Respiratory Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto-shi, Kumamoto, Japan., O'Grady SM; Departments of Animal Science, University of Minnesota, St. Paul, MN, United States.; Department of Integrative Biology and Physiology, University of Minnesota, St. Paul, MN, United States., Kopras EJ; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, United States., Meeker J; Division of Pediatric Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Morgan H; Division of Pediatric Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Ostmann AJ; Division of Pediatric Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Skala E; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Siefert ME; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Na CL; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Davidson CR; Division of Pediatric Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Gollomp K; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Mangalmurti N; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.; Pennsylvania Lung Biology Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States., Trapnell BC; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States., Clancy JP; Cystic Fibrosis Foundation, Bethesda, MD, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Jan 10; Vol. 13, pp. 1023553. Date of Electronic Publication: 2023 Jan 10 (Print Publication: 2022).

A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption.

Autor: Shima K; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Arumugam P; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Sallese A; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Horio Y; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Ma Y; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Trapnell C; Department of Genome Sciences, University of Washington, Seattle, Washington., Wessendarp M; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Chalk C; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., McCarthy C; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio., Carey BC; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Trapnell BC; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio., Suzuki T; Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.; Department of Respirology, Chiba University, Chiba, Japan.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2022 Mar 01; Vol. 322 (3), pp. L438-L448. Date of Electronic Publication: 2022 Jan 19.