Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Caren Linnemann"'
Autor:
Caren Linnemann, Filiz Sahin, Yangmengfan Chen, Karsten Falldorf, Michael Ronniger, Tina Histing, Andreas K. Nussler, Sabrina Ehnert
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14629 (2023)
Fracture-healing is a highly complex and timely orchestrated process. Non-healing fractures are still a major clinical problem and treatment remains difficult. A 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) was identified as
Externí odkaz:
https://doaj.org/article/45c54f3627c74615a2188b73015eff7d
Autor:
Caren Linnemann, Filiz Şahin, Ningna Li, Stefan Pscherer, Friedrich Götz, Tina Histing, Andreas K. Nussler, Sabrina Ehnert
Publikováno v:
Biology, Vol 12, Iss 8, p 1082 (2023)
Diabetes is a worldwide evolving disease with many associated complications, one of which is delayed or impaired wound healing. Appropriate wound healing strongly relies on the inflammatory reaction directly after injury, which is often altered in di
Externí odkaz:
https://doaj.org/article/7f91492559f443c6a5c409dbf4e19310
Autor:
Sabrina Ehnert, Caren Linnemann, Romina H. Aspera-Werz, Victor Häussling, Bianca Braun, Weidong Weng, Sheng Zhu, Kristian C. Ngamsri, Andreas Nussler
Publikováno v:
SciMedicine Journal, Vol 2, Iss 3, Pp 157-181 (2020)
Today, over 70 diseases and health conditions are known that negatively affect the bone quality directly or indirectly by their medical treatment, establishing the term metabolic bone disease. Already every third hospitalized patient in Europe suffer
Externí odkaz:
https://doaj.org/article/bee686f344424c1fb800fabaa9ddcab2
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16208 (2022)
Fracture healing is characterized by an inflammatory phase directly after fracture which has a strong impact on the healing outcome. Neutrophils are strong contributors here and can release neutrophil extracellular traps (NETs). NETs are found after
Externí odkaz:
https://doaj.org/article/c9a32e8823e347d598428275bfafed49
Autor:
Romina H. Aspera-Werz, Jonas Mück, Caren Linnemann, Moritz Herbst, Christoph Ihle, Tina Histing, Andreas K. Nussler, Sabrina Ehnert
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2424 (2022)
Smoking undoubtedly affects human health. Investigating 2318 representative patients at a level 1 trauma center identified delayed wound healing, tissue infections, and/or sepsis as main complications in smokers following trauma and orthopedic surger
Externí odkaz:
https://doaj.org/article/7bd168105a204d85a1c1d4fed71b9139
Autor:
Yangmengfan Chen, Maximilian M. Menger, Benedikt J. Braun, Sara Schweizer, Caren Linnemann, Karsten Falldorf, Michael Ronniger, Hongbo Wang, Tina Histing, Andreas K. Nussler, Sabrina Ehnert
Publikováno v:
Bioengineering, Vol 8, Iss 11, p 167 (2021)
Delayed fracture healing and fracture non-unions impose an enormous burden on individuals and society. Successful healing requires tight communication between immune cells and bone cells. Macrophages can be found in all healing phases. Due to their h
Externí odkaz:
https://doaj.org/article/dcd8e185d0fb492ab3aaa5b14478927b
Autor:
Caren Linnemann, Lorena Savini, Mika F. Rollmann, Tina Histing, Andreas K. Nussler, Sabrina Ehnert
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9212 (2021)
Diabetes mellitus is a main risk factor for delayed fracture healing and fracture non-unions. Successful fracture healing requires stimuli from different immune cells, known to be affected in diabetics. Especially, application of mononuclear cells ha
Externí odkaz:
https://doaj.org/article/fa24b59e57a44c23bc8174328d0588b9
Autor:
Marc Ruoß, Vanessa Kieber, Silas Rebholz, Caren Linnemann, Helen Rinderknecht, Victor Häussling, Marina Häcker, Leon H. H. Olde Damink, Sabrina Ehnert, Andreas K. Nussler
Publikováno v:
Methods and Protocols, Vol 3, Iss 1, p 1 (2019)
In order to increase the metabolic activity of human hepatocytes and liver cancer cell lines, many approaches have been reported in recent years. The metabolic activity could be increased mainly by cultivating the cells in 3D systems or co-cultures (
Externí odkaz:
https://doaj.org/article/f8a0e02bc5174a4fb5a845048f76f8eb
Autor:
Sabrina Ehnert, Caren Linnemann, Bianca Braun, Josephine Botsch, Karolin Leibiger, Philipp Hemmann, and Andreas K. Nussler
Publikováno v:
Methods and Protocols, Vol 2, Iss 3, p 63 (2019)
In eukaryotes, cellular functions are tightly controlled by diverse post-translational modifications (PTMs) of proteins. One such PTM affecting many proteins is the deimination of arginine to citrulline. This process, called citrullination is catalyz
Externí odkaz:
https://doaj.org/article/d0a93e5ffbc546ae8d8cfbb97541ce84
Autor:
Sabrina Ehnert, Caren Linnemann, Romina H. Aspera-Werz, Daria Bykova, Sara Biermann, Leonie Fecht, Peter M. De Zwart, Andreas K. Nussler, Fabian Stuby
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2239 (2018)
The cytokines secreted by immune cells have a large impact on the tissue, surrounding a fracture, e.g., by attraction of osteoprogenitor cells. However, the underlying mechanisms are not yet fully understood. Thus, this study aims at investigating mo
Externí odkaz:
https://doaj.org/article/29b8a0ed7fff408d97332f74a627f204