Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Carel J M, van Noesel"'
Autor:
Marthe Minderman, Hildo C. Lantermans, Leonie J. Grüneberg, Saskia A. G. M. Cillessen, Richard J. Bende, Carel J. M. van Noesel, Marie José Kersten, Steven T. Pals, Marcel Spaargaren
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The paracaspase mucosa-associated lymphoid tissue 1 (MALT1) is a protease and scaffold protein essential in propagating B-cell receptor (BCR) signaling to NF-κB. The deubiquitinating enzyme cylindromatosis (CYLD) is a recently discovered MA
Externí odkaz:
https://doaj.org/article/fa21a09a30c54eef9cb4825a4c293ec2
Autor:
Kristiaan J. Lenos, Sander Bach, Leandro Ferreira Moreno, Sanne ten Hoorn, Nina R. Sluiter, Sanne Bootsma, Felipe A. Vieira Braga, Lisanne E. Nijman, Tom van den Bosch, Daniel M. Miedema, Erik van Dijk, Bauke Ylstra, Ruth Kulicke, Fred P. Davis, Nicolas Stransky, Gromoslaw A. Smolen, Robert R. J. Coebergh van den Braak, Jan N. M. IJzermans, John W. M. Martens, Sally Hallam, Andrew D. Beggs, Geert J. P. L. Kops, Nico Lansu, Vivian P. Bastiaenen, Charlotte E. L. Klaver, Maria C. Lecca, Khalid El Makrini, Clara C. Elbers, Mark P. G. Dings, Carel J. M. van Noesel, Onno Kranenburg, Jan Paul Medema, Jan Koster, Lianne Koens, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. de Hingh, Maarten F. Bijlsma, Jurriaan B. Tuynman, Louis Vermeulen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Colorectal cancer can lead to the development of peritoneal metastases, which are associated with worse disease outcome. Here, the authors characterize peritoneal metastases from 52 patients using RNA-seq and mutational sequencing and show a distinct
Externí odkaz:
https://doaj.org/article/369abe186b03465f8bac79e90a4d4606
Autor:
Henry J C de Vries, Johannes Berkhof, Jan M Prins, Maarten F Schim van der Loeff, Renske D M Steenbergen, Carel J M van Noesel, Fernando Dias Gonçalves Lima, Ramon P van der Zee, Stèfanie Dick
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Introduction Anal cancer precursors, or high-grade anal intraepithelial neoplasia (HGAIN), are highly prevalent in HIV-seropositive (HIV+) men who have sex with men (MSM). Around 30% of lesions regress within 1 year, but current histopathological ass
Externí odkaz:
https://doaj.org/article/50ee2fdeb2a34376a0d50683d2e91040
Autor:
Paul G. Kemps, Timo C. E. Zondag, Helga B. Arnardóttir, Nienke Solleveld-Westerink, Jelske Borst, Eline C. Steenwijk, Demi van Egmond, Joost F. Swennenhuis, Ellen Stelloo, Irene Trambusti, Robert M. Verdijk, Carel J. M. van Noesel, Arjen H. G. Cleven, Marijn A. Scheijde-Vermeulen, Marco J. Koudijs, Lenka Krsková, Cynthia Hawkins, R. Maarten Egeler, Jesper Brok, Tatiana von Bahr Greenwood, Karel Svojgr, Auke Beishuizen, Jan A. M. van Laar, Ulrike Pötschger, Caroline Hutter, Elena Sieni, Milen Minkov, Oussama Abla, Tom van Wezel, Cor van den Bos, Astrid G. S. van Halteren
Publikováno v:
Blood advances, 7(4), 664-679. American Society of Hematology
Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder caused by somatic genetic alterations in hematopoietic precursor cells differentiating into CD1a+/CD207+ histiocytes. LCH clinical manifestation is highly heterogeneous. BRAF and MAP2K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8313baedb40f4a65321041d0cf2628
https://doi.org/10.1182/bloodadvances.2022007947
https://doi.org/10.1182/bloodadvances.2022007947
Autor:
Bernadette Schurink, PhD, Eva Roos, PhD, Teodora Radonic, PhD, Ellis Barbe, PhD, Catherine S C Bouman, PhD, Hans H de Boer, PhD, Godelieve J de Bree, PhD, Esther B Bulle, MD, Eleonora M Aronica, ProfPhD, Sandrine Florquin, ProfPhD, Judith Fronczek, PhD, Leo M A Heunks, ProfPhD, Menno D de Jong, ProfPhD, Lihui Guo, PhD, Romy du Long, MD, Rene Lutter, PhD, Pam C G Molenaar, BSc, E Andra Neefjes-Borst, MD, Hans W M Niessen, ProfPhD, Carel J M van Noesel, ProfPhD, Joris J T H Roelofs, PhD, Eric J Snijder, ProfPhD, Eline C Soer, PhD, Joanne Verheij, PhD, Alexander P J Vlaar, PhD, Wim Vos, MSc, Nicole N van der Wel, PhD, Allard C van der Wal, ProfPhD, Paul van der Valk, ProfPhD, Marianna Bugiani, PhD
Publikováno v:
The Lancet Microbe, Vol 1, Iss 7, Pp e290-e299 (2020)
Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets multiple organs and causes severe coagulopathy. Histopathological organ changes might not only be attributable to a direct virus-induced effect, but also the im
Externí odkaz:
https://doaj.org/article/9c826f4dae8a4c1993bc4d9880a5fd0c
Autor:
Paul G. Kemps, Timo C. Zondag, Eline C. Steenwijk, Quirine Andriessen, Jelske Borst, Sandra Vloemans, Dave L. Roelen, Lenard M. Voortman, Robert M. Verdijk, Carel J. M. van Noesel, Arjen H. G. Cleven, Cynthia Hawkins, Veronica Lang, Arnoud H. de Ru, George M. C. Janssen, Geert W. Haasnoot, Kees L. M. C. Franken, Ronald van Eijk, Nienke Solleveld-Westerink, Tom van Wezel, R. Maarten Egeler, Auke Beishuizen, Jan A. M. van Laar, Oussama Abla, Cor van den Bos, Peter A. van Veelen, Astrid G. S. van Halteren
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Langerhans Cell Histiocytosis (LCH) is a neoplastic disorder of hematopoietic origin characterized by inflammatory lesions containing clonal histiocytes (LCH-cells) intermixed with various immune cells, including T cells. In 50–60% of LCH-patients,
Externí odkaz:
https://doaj.org/article/e72482c223694d18a86b7155b95eb24c
Autor:
Paul van der Leest, Emma M Ketelaar, Carel J M van Noesel, Daan van den Broek, Robert A A van Boerdonk, Birgit Deiman, Naomi Rifaela, Robert van der Geize, Cornelis J J Huijsmans, Ernst Jan M Speel, Maartje J Geerlings, Ron H N van Schaik, Maurice P H M Jansen, Ria Dane-Vogelaar, Else Driehuis, Mathie P G Leers, Grigory Sidorenkov, Menno Tamminga, Léon C van Kempen, Ed Schuuring
Publikováno v:
Clinical Chemistry, 68(7), 963-972. American Association for Clinical Chemistry Inc.
Clinical Chemistry, 68(7). AMER ASSOC CLINICAL CHEMISTRY
Clinical Chemistry, 68(7), 963-972. American Association for Clinical Chemistry
Clinical chemistry, 68(7), 963-972. American Association for Clinical Chemistry Inc.
Clinical Chemistry, 68(7). AMER ASSOC CLINICAL CHEMISTRY
Clinical Chemistry, 68(7), 963-972. American Association for Clinical Chemistry
Clinical chemistry, 68(7), 963-972. American Association for Clinical Chemistry Inc.
Background Efficient recovery of circulating tumor DNA (ctDNA) depends on the quantity and quality of circulating cell-free DNA (ccfDNA). Here, we evaluated whether various ccfDNA extraction methods routinely applied in Dutch laboratories affect ccfD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906fa9055b7cf6374bd4037a9f4ceb37
http://www.scopus.com/inward/record.url?scp=85134083629&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85134083629&partnerID=8YFLogxK
Autor:
Arthur S. Aelvoet, Daniël R. Hoekman, Bert J. W. Redeker, Jitske Weegenaar, Evelien Dekker, Carel J. M. van Noesel, Floor A. M. Duijkers
Publikováno v:
Familial cancer, 22(1), 49-54. Springer Netherlands
Biallelic MSH3 germline variants are a rare cause of adenomatous polyposis as yet reported in two small families only. We describe the phenotype of a third family, the largest thus far, with adenomatous polyposis related to compound heterozygous MSH3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6126b2592befc062ebb856b24f497379
https://doi.org/10.1007/s10689-022-00297-x
https://doi.org/10.1007/s10689-022-00297-x
Autor:
Willemijn S M E Theelen, Thomas Kuilman, Katja Schulze, Wei Zou, Oscar Krijgsman, Dennis D G C Peters, Sten Cornelissen, Kim Monkhorst, Pranamee Sarma, Teiko Sumiyoshi, Lukas C Amler, Stefan M Willems, Johannes L G Blaauwgeers, Carel J M van Noesel, Daniel S Peeper, Michel M van den Heuvel, Marcin Kowanetz
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216864 (2019)
BackgroundIn non-small cell lung cancer (NSCLC), PD-L1 expression on either tumor cells (TC) or both TC and tumor-infiltrating immune cells (IC) is currently the most used biomarker in cancer immunotherapy. However, the mechanisms involved in PD-L1 r
Externí odkaz:
https://doaj.org/article/71ec07804c5045b0afac420650e42855
Autor:
Linda J. Valentijn, Ellen M. Westerhout, Rogier Versteeg, Alvin Chan, Arjan Lakeman, Peter van Sluis, Natalia E Nowakowska, Mohamed Hamdi, Igor Adameyko, Nancy E. Hasselt, Boris Bleijlevens, Tim van Groningen, Franciska Haneveld, Jan Koster, Carel J. M. van Noesel, Nurdan Akogul, Richard Volckmann, Peter Stroeken, Danny A. Zwijnenburg, Jennemiek van Arkel, Johan van Nes
Publikováno v:
Cancer research, 82(3), 484-496. American Association for Cancer Research Inc.
Cancer therapy frequently fails due to the emergence of resistance. Many tumors include phenotypically immature tumor cells, which have been implicated in therapy resistance. Neuroblastoma cells can adopt a lineage-committed adrenergic (ADRN) or an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8eca38a6b36d94471b13429c50ac12
http://www.scopus.com/inward/record.url?scp=85124056607&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85124056607&partnerID=8YFLogxK