Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Careen K. Tang"'
Autor:
Terrance Grant Johns, Haizhong Feng, Careen K Tang, Ronald L. Hamilton, Tim R. Fenton, Tao Cheng, Shi Yuan Cheng, Jann N. Sarkaria, Frank B. Furnari, Yanxin Li, Michael J. Jarzynka, Webster K. Cavenee, Susan Keezer, Kristiina Vuori, Ryo Nishikawa, Bo Hu
Publikováno v:
Proceedings of the National Academy of Sciences. 109:3018-3023
Glioblastoma, the most common primary malignant cancer of the brain, is characterized by rapid tumor growth and infiltration of tumor cells throughout the brain. These traits cause glioblastomas to be highly resistant to current therapies with a resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd24169a7ee0018ca78547777d74e75
https://doi.org/10.1073/pnas.1121457109
https://doi.org/10.1073/pnas.1121457109
Publikováno v:
Cancer Letters. 306:43-51
Our previous report has shown that the constitutively activated EGFR variant, EGFRvIII, up-regulates the pro-metastatic chemokine receptor CXCR4 in breast cancer cells. Here we evaluated the biological effect and cell signaling effects of silencing C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bccf00cfe98103c6c6f44c99310cc5
https://doi.org/10.1016/j.canlet.2011.02.024
https://doi.org/10.1016/j.canlet.2011.02.024
Autor:
Careen K. Tang, David S. Salomon, Tomoko Fukuda, Takayuki Otani, Tadahiro Nagaoka, Masaharu Seno, Toshihiro Hashizume
Publikováno v:
Biotechnology Letters. 32:361-366
The extracellular domains (ECD) of epidermal growth factor receptors, ErbB1, 2, 3 and 4, were designed as soluble dimeric forms. Each ECD was fused to a short hinge region derived from IgG, such that the stable dimer could be formed with disulfide br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee784b4001c06f786026e4bc68dc319a
https://doi.org/10.1007/s10529-009-0160-9
https://doi.org/10.1007/s10529-009-0160-9
Publikováno v:
International Journal of Cancer. 125:1805-1813
Transducer of ErbB-2 (TOB) is a member of the TOB/Btg gene family. A role for TOB in the suppression of human tumorigenesis has been proposed, based on the observations that TOB-knockout mice spontaneously form tumors and TOB expression is lost in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c69cb553a78093e8093927b8ddb200f
https://doi.org/10.1002/ijc.24490
https://doi.org/10.1002/ijc.24490
Publikováno v:
International Journal of Cancer. 126:1850-1860
The expression of the potent, constitutively activated EGFR variant, EGFRvIII, has been linked to breast cancer metastasis, but the mechanisms of EGFRvIII and CXCR4 crosstalk, which may facilitate breast cancer invasion, have never been explored. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82410ff586c021b15a2f084112f740ff
https://doi.org/10.1002/ijc.24964
https://doi.org/10.1002/ijc.24964
Publikováno v:
International Journal of Cancer. 125:2021-2028
The tumor specific, ligand-independent, constitutively active Epidermal Growth Factor Receptor (EGFR) variant, EGFRvIII, remains understudied in breast cancer. Here, we report that expression of EGFRvIII in the ErbB-2-overexpressing, estrogen-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfbb92f85f2f86f89cdb5c0ba1601fd
https://doi.org/10.1002/ijc.24540
https://doi.org/10.1002/ijc.24540
Autor:
Pradip Roy-Burman, Surinder K. Batra, Shi Yuan Cheng, Menashe Bar-Eli, Shijie Sheng, Wen Tien Chen, Victoria L. Seewaldt, Lisa M. Coussens, Ramon Parsons, Yves A. De Clerck, Lucia R. Languino, James B. McCarthy, Srikumar Chellappan, Michael B. Cohen, Bernard E. Weissman, Anne E. Cress, Stephan Ladisch, Careen K. Tang, Dihua Yu
Publikováno v:
Cancer Biology & Therapy. 5:1588-1599
A Workshop of the Tumor Progression and Metastasis NIH Study Section In Honor of Dr. Martin L. PadarathsinghMay 31, 2006, Georgetown, Washington, DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ebad8ef0a146822f0bfccdce75b280e
https://doi.org/10.4161/cbt.5.12.3660
https://doi.org/10.4161/cbt.5.12.3660
Autor:
Lyndsay Harris, Marina Cardillo, Mai M. Hijazi, Karen Rosenberg, Cheryl Cho, D. Yang, Careen K. Tang, Ruth Lupu, C. Perez
Publikováno v:
Breast Cancer Research and Treatment. 38:57-66
The erbB-2 receptor plays an important role in the prognosis of breast cancer and is expressed at high levels in nearly 30% of tumors in breast cancer patients. While evidence accumulates to support the relationship between erbB-2 overexpression and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318ed6095fd64ee9e9faf853b587e6e2
https://doi.org/10.1007/bf01803784
https://doi.org/10.1007/bf01803784
Autor:
Sophie A. Lelièvre, Matthew Fred, Theodore A. Toth, Elias J. Sobrino Najul, Hua Su, Careen K. Tang, Crystal Ng
Publikováno v:
Cancer letters. 307(2)
Recent studies have shown that CXCR4 is associated with tumor metastasis. Elevated levels of CXCR4 are also detected in a high percentage of DCIS cases. The high frequency of CXCR4 expression in DCIS suggests that many DCIS cases are "primed" for inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deef00e33a009f494d8ac64cd4e3e189
https://pubmed.ncbi.nlm.nih.gov/21530075
https://pubmed.ncbi.nlm.nih.gov/21530075
Publikováno v:
Cancer biologytherapy. 7(11)
Elevated levels of epidermal growth factor receptor (EGFR) have been detected in a variety of human cancers. Several reports have demonstrated that the Type III EGF receptor deletion-mutant (EGFRvIII) is frequently detected in various human cancers,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dfa93c34bc202bd8ee8e1961ed0ee8
https://pubmed.ncbi.nlm.nih.gov/18787418
https://pubmed.ncbi.nlm.nih.gov/18787418