Hydroethanolic extract from Endopleura uchi (Huber) Cuatrecasas and its marker bergenin: Toxicological and pharmacokinetic studies in silico and in vivo on zebrafish.

Autor: de Sá Hyacienth BM; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Postgraduate Program in Biodiversity and Biotechnology of the Legal Amazon of the BIONORTE Network, Department of Biological Sciences and Health, Federal University of Amapá, Macapá, AP, Brazil., Tavares Picanço KR; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Sánchez-Ortiz BL; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Laboratory of Natural Product Pharmacology, Department of Pharmacy, Faculty of Chemistry, National Autonomous University of Mexico, University City, Coyoacán, Zip Code 04510 Mexico City, Mexico., Barros Silva L; Federal University of Amapá, Laboratory of Modeling and Computational Chemistry, Department of Biological Sciences and Health, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Matias Pereira AC; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Machado Góes LD; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Sousa Borges R; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Cardoso Ataíde R; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Dos Santos CBR; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Federal University of Amapá, Laboratory of Modeling and Computational Chemistry, Department of Biological Sciences and Health, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., de Oliveira Carvalho H; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil., Gonzalez Anduaga GM; Laboratory of Natural Product Pharmacology, Department of Pharmacy, Faculty of Chemistry, National Autonomous University of Mexico, University City, Coyoacán, Zip Code 04510 Mexico City, Mexico., Navarrete A; Laboratory of Natural Product Pharmacology, Department of Pharmacy, Faculty of Chemistry, National Autonomous University of Mexico, University City, Coyoacán, Zip Code 04510 Mexico City, Mexico., Tavares Carvalho JC; Laboratory of Pharmaceutical Research, Department of Biological Sciences and Health, Federal University of Amapá, Juscelino Kubitschek Street, Marco Zero Campus, Zip Code 68903-419, Macapá, AP, Brazil.; Postgraduate Program in Biodiversity and Biotechnology of the Legal Amazon of the BIONORTE Network, Department of Biological Sciences and Health, Federal University of Amapá, Macapá, AP, Brazil.

Publikováno v: Toxicology reports [Toxicol Rep] 2020 Jan 27; Vol. 7, pp. 217-232. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020).