New Insights into Structural Disorder in Human Respiratory Syncytial Virus Phosphoprotein and Implications for Binding of Protein Partners

Autor: Pereira, Nelson, Cardone, Christophe, Lassoued, Safa, Galloux, Marie, Fix, Jenna, Assrir, Nadine, Lescop, Ewen, Bontems, François, Eléouët, Jean-François, Sizun, Christina

Publikováno v: In Journal of Biological Chemistry 10 February 2017 292(6):2120-2131

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Structural caracterizsation by NMR of interactions between proteins of respiratory syncytial virus polymerase complex and cellular partner proteins

Autor: Cardone, Christophe

Publikováno v: Biologie structurale [q-bio.BM]. Université Paris-Saclay, 2019. Français. ⟨NNT : 2019SACLS586⟩

Human respiratory syncytial virus (hRSV) is the main pathogen responsible for bronchiolitis. The RNA polymerase complex (RdRp) of hRSV, necessary for the replication of its genome, is composed at least of the catalytic subunit (L), its main cofactor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7cc23597003de16441d33dad0aa32414
https://tel.archives-ouvertes.fr/tel-02462886/document

RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

Autor: Richard, Charles-Adrien, Rincheval, Vincent, Lassoued, Safa, fix, Jenna, Cardone, Christophe, Esneau, Camille, Nekhai, Sergei, Galloux, Marie, Rameix-Welti, Marie-Anne, Sizun, Christina, Eléouët, Jean Francois

Publikováno v: Plos Pathogens 3 (14), e1006920. (2018)
PLOS Pathogens
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2018, 14 (3), pp.e1006920. ⟨10.1371/journal.ppat.1006920⟩
PLoS Pathogens, Vol 14, Iss 3, p e1006920 (2018)

Respiratory syncytial virus (RSV) RNA synthesis occurs in cytoplasmic inclusion bodies (IBs) in which all the components of the viral RNA polymerase are concentrated. In this work, we show that RSV P protein recruits the essential RSV transcription f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44683a7fe1bc4076f88a268e2f8dfc02
http://prodinra.inra.fr/record/423723

RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription.

Autor: Richard CA; Unité de Virologie et Immunologie Moléculaires (UR892), INRA, Université Paris-Saclay, Jouy-en-Josas, France., Rincheval V; UMR1173, INSERM, Université de Versailles St. Quentin, Montigny le Bretonneux, France., Lassoued S; Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Avenue de la Terrasse, Gif-sur-Yvette, France., Fix J; Unité de Virologie et Immunologie Moléculaires (UR892), INRA, Université Paris-Saclay, Jouy-en-Josas, France., Cardone C; Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Avenue de la Terrasse, Gif-sur-Yvette, France., Esneau C; Unité de Virologie et Immunologie Moléculaires (UR892), INRA, Université Paris-Saclay, Jouy-en-Josas, France., Nekhai S; Center for Sickle Cell Disease and Department of Medicine, Howard University, Washington, D. C., United States of America., Galloux M; Unité de Virologie et Immunologie Moléculaires (UR892), INRA, Université Paris-Saclay, Jouy-en-Josas, France., Rameix-Welti MA; UMR1173, INSERM, Université de Versailles St. Quentin, Montigny le Bretonneux, France.; AP-HP, Laboratoire de Microbiologie, Hôpital Ambroise Paré, Boulogne-Billancourt, France., Sizun C; Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Avenue de la Terrasse, Gif-sur-Yvette, France., Eléouët JF; Unité de Virologie et Immunologie Moléculaires (UR892), INRA, Université Paris-Saclay, Jouy-en-Josas, France.

Publikováno v: PLoS pathogens [PLoS Pathog] 2018 Feb 28; Vol. 14 (3), pp. e1006920. Date of Electronic Publication: 2018 Feb 28 (Print Publication: 2018).