Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Cardiovascular Disorders/Myocardial Infarction"'
Autor:
Andrew Jefferson, Robin P. Choudhury, Kathryn J. Wood, Martina A. McAteer, Jürgen E. Schneider, S Chapman, Kulveer Mankia, Ye Chen, J Digby, Asim M. Akhtar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12800 (2010)
PLoS ONE, Vol 5, Iss 9, p e12800 (2010)
RATIONALE AND OBJECTIVE: Vascular cell adhesion molecule-1 (VCAM-1) is upregulated in ischemia reperfusion injury (IRI), persisting after restoration of blood flow. We hypothesized that microparticles of iron oxide targeting VCAM-1 (VCAM-MPIO) would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83723570070fbe2cd70722cad0e5f15f
https://doi.org/10.1371/journal.pone.0012800
https://doi.org/10.1371/journal.pone.0012800
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 8, p e6752 (2009)
PLoS ONE, Vol 4, Iss 8, p e6752 (2009)
Background: Mammalian cardiac myocytes withdraw from the cell cycle during post-natal development, resulting in a nonproliferating, fully differentiated adult phenotype that is unable to repair damage to the myocardium, such as occurs following a myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623490b9b0b21a1daf15ee5ae9474ef8
https://ora.ox.ac.uk/objects/uuid:9261450a-44ab-4a1d-a3f0-0026223d1296
https://ora.ox.ac.uk/objects/uuid:9261450a-44ab-4a1d-a3f0-0026223d1296
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 2, p e14669 (2011)
PLoS ONE, Vol 6, Iss 2, p e14669 (2011)
BACKGROUND: Despite its efficacy and cost-effectiveness, exercise-based cardiac rehabilitation is undertaken by less than one-third of clinically eligible cardiac patients in every country for which data is available. Reasons for non-participation in
Autor:
Antonio L Dans, Koon Teo, Peggy Gao, Jyh-Hong Chen, Kim Jae-Hyung, Khalid Yusoff, Suphachai Chaithiraphan, Jun Zhu, Liu Lisheng, Salim Yusuf, Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial Investigators
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e13694 (2010)
PLoS ONE
PLoS ONE
Background and Objectives Results of the recently published ONTARGET study (The Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial) showed that telmisartan (80 mg/day) was non-inferior to ramipril (10 mg/day) in reducing
Autor:
Stephan Fichtlscherer, Heinz-Peter Schultheiss, Andreas M. Zeiher, Alexandra Aicher, Caroline Schmidt-Lucke, Carsten Tschöpe, Stefanie Dimmeler
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e13790 (2010)
PLoS ONE, Vol 5, Iss 11, p e13790 (2010)
AimsCirculating endothelial progenitor cells (EPC), involved in endothelial regeneration, neovascularisation, and determination of prognosis in cardiovascular disease can be characterised with functional assays or using immunofluorescence and flow cy
Autor:
Philip G. Jones, Daniel P. Kelly, Howard L. McLeod, Amber L. Beitelshees, Sharon Cresci, Gerald W. Dorn, Janice M. Huss, John A. Spertus, Matt R Minton
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12584 (2010)
PLoS ONE, Vol 5, Iss 9, p e12584 (2010)
Activation of peroxisome proliferator-activated receptor alpha (PPARα) occurs in animal models of diabetes (DM) and is implicated in pathological responses to myocardial ischemia. Using bioinformatics, we identified a single nucleotide polymorphism
Autor:
Andre R. Arellano, Charles M. Rowland, James J. Devlin, Edward A. Ruiz-Narváez, Hannia Campos, Joseph J. Catanese, Lance A. Bare, Frank M. Sacks, Carmen H. Tong
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE
PLoS ONE
Background and Methodology: The 719Arg allele of KIF6 (rs20455) was associated with coronary events in Caucasian participants of five prospective studies. We investigated whether this KIF6 variant was associated with non-fatal myocardial infarction (
Autor:
Tao-Sheng Li, Yiqiang Zhang, M. Roselle Abraham, Kolja Wawrowsky, Giselle Galang, Charles Wang, Konstantinos Malliaras, Ke Cheng, Shuo Tsan Lee, Eduardo Marbán
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12559 (2010)
PLoS ONE, Vol 5, Iss 9, p e12559 (2010)
BackgroundIt has long been thought that mammalian cardiomyocytes are terminally-differentiated and unable to proliferate. However, myocytes in more primitive animals such as zebrafish are able to dedifferentiate and proliferate to regenerate amputate
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12150 (2010)
PLoS ONE
PLoS ONE
BackgroundSurvivors of anterior MI are at increased risk for stroke with predilection to form ventricular thrombus. Commonly patients are discharged on dual antiplatelet therapy. Given the frequency of early coronary reperfusion and risk of bleeding,
Autor:
David A. Saint, Steven Weiss
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e14103 (2010)
PLoS ONE, Vol 5, Iss 11, p e14103 (2010)
BACKGROUND: The potential of the cardiac persistent sodium current as a target for protection of the myocardium from ischaemia and reperfusion injury is gaining increasing interest. We have investigated the anti-ischaemic and antiarrhythmic effects o