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pro vyhledávání: '"Cardiotonic drugs"'
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Autor:
D. A. Lomov
Publikováno v:
Russian Journal of Organic Chemistry. 55:1093-1098
Readily available 4-methyl-3-nitrobenzenesulfonic acid and 2-methyl-5-nitrophenol were used to develop two alternative approaches to the synthesis of 2-methoxy-4-(methylsulfanyl)benzoic acid in total yields of 17% and 37%, respectively. The synthesis
Autor:
Roman A. Knyazev, Arkady R. Kolpakov
Publikováno v:
Cardiovascularhematological disorders drug targets. 21(2)
Medicinal preparations currently used for the treatment of patients with chronic cardiac failure involve those that reduce the heart load (vasodilators, diuretics, beta-blockers, and angiotensin- converting enzyme (ACE) inhibitors). Cardiotonic drugs
Publikováno v:
Clinics in perinatology. 46(2)
There is a distinct lack of age-appropriate cardiotonic drugs, and adult derived formulations continue to be administered, without evidence-based knowledge on their dosing, safety, efficacy, and long-term effects. Dopamine remains the most commonly s
Autor:
Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin), Елена (Elena) Николаевна (Nikolayevna) Зайцева (Zaitseva), Татьяна (Tat'yana) Владимировна (Vladimirovna) Морозова (Morozova), Ольга (Ol'ga) Евгеньевна (Evgen'evna) Правдивцева (Pravdivtseva), Елена (Elena) Владимировна (Vladimirovna) Авдеева (Avdeeva), Анна (Anna) Владимировна (Vladimirovna) Куркина (Kurkina), Альберт (Al'bert) Иванович (Ivanovich) Агапов (Agapov)
Publikováno v:
chemistry of plant raw material; No 4 (2018); 105-112
Химия растительного сырья; № 4 (2018); 105-112
Химия растительного сырья; № 4 (2018); 105-112
Nowadays flowers and fruits of various types of hawthorn are widely used as cardiotonic drugs in Russian Federation. In our opinion a promising species for harvesting raw materials is Quebec hawthorn (Crataegus submollis Sarg., Rosaceae). Quebec hawt
Autor:
Gauthaman Karunakaran
Publikováno v:
Ancient Science of Life
Background: The present study was designed to investigate the cardio protective role of chronic oral administration of methanolic extract of Terminalia arjuna bark in in-vitro myocardial ischemic reperfusion injury and the induction of HSP72. Materia
Publikováno v:
European Journal of Medicinal Chemistry. 40:1163-1167
3,4- trans -4-Aryl-3-(1-pyridinio)-1,2,3,4-tetrahydropyridine-6-thiolates 6 – 11 were prepared by a Michael reaction of N -acetonylpyridinium chloride with 3-aryl-2-cyanothioacrylamides or by a one-pot three-carbon condensation of N -acetonylpyridi
Publikováno v:
Synlett. :2287-2290
A set of 5-(2-hydroxybenzoyl)-pyrid-2-ones, which are analogous to cardiotonic drugs such as milrinone, has been prepared in high yield by recyclization of 3-formylchromones with acetic acid amides having at the α-position an electron-withdrawing gr
Autor:
Javier Bordallo, Manuel Sánchez, Agustín Hidalgo, Rosario Cortina, Lorena Secades, Lucía Velasco
Publikováno v:
Pharmacology. 70:118-122
Pharmacological concentrations of androgens are known to elicit a rapid positive inotropism in isolated left atrium of male rats. Upon short-term exposure to androgens, an increase in intracellular cAMP levels has been observed, though delayed with r
Autor:
Kurt R.H. Repke
Publikováno v:
Drug Discovery Today. 2:110-116
Increased incidence and prevalence of congestive heart failure make the discovery of novel positive inotropes (i.e. agents that increase the peak force of contraction of the heart muscle) a priority. Cardiac glycosides currently in use are inadequate