Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Cardiomyocyte maturation"'
Autor:
Jake Ireland, Kristopher A. Kilian
Publikováno v:
Matrix Biology Plus, Vol 24, Iss , Pp 100160- (2024)
Human embryonic stem cell-derived cardiomyocytes (hESC-CM) are a promising source of cardiac cells for disease modelling and regenerative medicine. However, current protocols invariably lead to mixed population of cardiac cell types and often generat
Externí odkaz:
https://doaj.org/article/e5e0ef4515044b329177041402fd731d
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Cell therapy is a potential novel treatment for cardiac regeneration and numerous studies have attempted to transplant cells to regenerate the myocardium lost during myocardial infarction. To date, only minimal improvements to cardiac functi
Externí odkaz:
https://doaj.org/article/2e886730de8d4680b41bdbf2cf680658
Autor:
Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract Cardiomyocyte maturation is the final stage of heart development, and abnormal cardiomyocyte maturation will lead to serious heart diseases. CXXC zinc finger protein 1 (Cfp1), a key epigenetic factor in multi‐lineage cell development, rema
Externí odkaz:
https://doaj.org/article/0a81858492eb4ffe99491a74c358ee28
Autor:
Kornél Kistamás, Federica Lamberto, Raminta Vaiciuleviciute, Filipa Leal, Suchitra Muenthaisong, Luis Marte, Paula Subías-Beltrán, Aidas Alaburda, Dina N. Arvanitis, Melinda Zana, Pedro F. Costa, Eiva Bernotiene, Christian Bergaud, András Dinnyés
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9186 (2024)
One of the many unresolved obstacles in the field of cardiovascular research is an uncompromising in vitro cardiac model. While primary cell sources from animal models offer both advantages and disadvantages, efforts over the past half-century have a
Externí odkaz:
https://doaj.org/article/a3cf5b1e321048088d970884cbb630b4
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Background Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdevelope
Externí odkaz:
https://doaj.org/article/b736361c07044f5da99680857c9d2df7
Autor:
Yukang Wu, Xudong Guo, Tong Han, Ke Feng, Peng Zhang, Yanxin Xu, Yiwei Yang, Yuchen Xia, Yang Chen, Jiajie Xi, Huangtian Yang, Xiaoping Wan, Jiuhong Kang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 481-497 (2022)
The immature phenotype of embryonic stem cell-derived cardiomyocytes (ESC-CMs) limits their application. However, the molecular mechanisms of cardiomyocyte maturation remain largely unexplored. This study found that overexpression of long noncoding R
Externí odkaz:
https://doaj.org/article/9327f241e1ac4083ad638c3fef6c07de
Publikováno v:
Cells, Vol 13, Iss 3, p 235 (2024)
Heart development is a spatiotemporally regulated process that extends from the embryonic phase to postnatal stages. Disruption of this highly orchestrated process can lead to congenital heart disease or predispose the heart to cardiomyopathy or hear
Externí odkaz:
https://doaj.org/article/36d5915295114ab48e8902aecff92f7e
Autor:
Yao Tan, Tingting Lu, Ying Chen, Nevin Witman, Bingqian Yan, Li Yang, Minglu Liu, Yiqi Gong, Xuefeng Ai, Runjiao Luo, Huijing Wang, Wei Wang, Wei Fu
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Engineering a conduction‐consistent cardiac patch has direct implications to biomedical research. However, there is difficulty in obtaining and maintaining a system that allows researchers to study physiologically relevant cardiac developm
Externí odkaz:
https://doaj.org/article/daf1d36e827b44b798d5e86cd6a95e25
Autor:
Irene Bissoli, Stefania D’Adamo, Carla Pignatti, Giulio Agnetti, Flavio Flamigni, Silvia Cetrullo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/bcba498af77b4ee7b9c9d460bfdd44e4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.