Zobrazeno 1 - 10
of 3 694
pro vyhledávání: '"Cardiac toxicity"'
Autor:
Nyambura Kariuki, Esther Kimani, Christine Jowi, Dalton Wamalwa, Jacky Y. Suen, John F. Fraser, Nchafatso G. Obonyo
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Introduction Use of doxorubicin, an anthracycline chemotherapeutic agent has been associated with late-occurring cardiac toxicities. Detection of early-occurring cardiac effects of cancer chemotherapy is essential to prevent occurrence of ad
Externí odkaz:
https://doaj.org/article/c655bde285eb42c7ad14a6aa22340346
Autor:
Isabelle Senechal, Nikolaos Vogiatzakis, Maria Sol Andres, Jieli Tong, Sivatharshini Ramalingam, Stuart D Rosen, Alexander R Lyon, Muhummad Sohaib Nazir
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-5 (2024)
Abstract Panitumumab is a human immunoglobulin monoclonal antibody designed to target the epidermal growth factor receptor (EGFR) which is used in the treatment of metastatic colorectal cancer alone or in combination with chemotherapy. In this report
Externí odkaz:
https://doaj.org/article/79072bc4cdbc402b95547058e29b3e96
Autor:
A. V. Kukurika
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 11-12, Pp 67-74 (2024)
The review analyzes the research articles, guidelines, and clinical trial results on the effect of fluoroquinolones, bedaquiline, nitroimidazoles, and clofazimine on QTc prolongation. The importance of timely and regular monitoring of cardiotoxicit
Externí odkaz:
https://doaj.org/article/1a6675b27038447ea0c3d4c3d19dac85
Autor:
Kathryn Banfill, PhD, FRCR, Thomas Marchant, PhD, Alan McWilliam, PhD, Joseph Wood, PhD, Matthias Schmitt, MD, PhD, Azadeh Abravan, PhD, Gareth Price, PhD, Marcel van Herk, PhD, Corinne Faivre-Finn, PhD, FRCR
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100742- (2024)
Increasing radiotherapy dose to select cardiac structures is associated with cardiac events and premature death. Previous studies have found a dose–response relationship for structures at the base of the heart.We have defined a new cardiac anatomic
Externí odkaz:
https://doaj.org/article/395c564086234d0e8fcbd739e3cb53aa
Autor:
Syeda Sania Zahara, Mehrab Khalil, Moazama Batool, Muhammad Faisal Hayat, Bader O. Almutairi, Mian Nadeem Riaz
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 7, Pp 103260- (2024)
Arsenic is a lethal toxicant found ubiquitously in the ecosystem which adversely affects the body organs including the heart. Pachypodol (PCHP) is a natural flavone which exhibits substantial pharmacotherapeutic potentials. The rats (n = 24) were dis
Externí odkaz:
https://doaj.org/article/37c86d0f298d44bd978f9c5f70ad1e25
Autor:
Chang-Young Yoon, Kyongmi Chon, Bala Murali Krishna Vasamsetti, Sojeong Hwang, Kyeong-Hun Park, Kee Sung Kyung
Publikováno v:
Fishes, Vol 9, Iss 11, p 425 (2024)
Iprodione (IDN) is a broad-spectrum fungicide used to treat various fungal infections in plants. Despite its extensive use, assessment of its toxicity in aquatic organisms remains incomplete. This study investigated the deleterious effects of IDN usi
Externí odkaz:
https://doaj.org/article/b9c2eec09805496ea293d297f0d6bb6f
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Traditional approaches to preclinical drug safety assessment have generally protected human patients from unintended adverse effects. However, these assessments typically occur too late to make changes in the formulation or in phase 1 and beyond, are
Externí odkaz:
https://doaj.org/article/65edf2193e6245698c93414965eb96d2
Autor:
Julie A. Bradley, MD, MHCDS, Jayden Gracie, MD, Raymond B. Mailhot Vega, MD, MPH, Eric D. Brooks, MD, MHS, Tenna Burchianti, ARNP, Oluwadamilola T. Oladeru, MD, MA, MBA, Xiaoying Liang, PhD, Nancy P. Mendenhall, MD
Publikováno v:
International Journal of Particle Therapy, Vol 10, Iss 2, Pp 94-104 (2023)
Purpose: Male breast cancer treatment involves multimodality therapy, including radiation therapy; nevertheless, few men have received proton therapy (PT) for it. Further, heart disease is an established leading cause of death in men, and radiation t
Externí odkaz:
https://doaj.org/article/dae50e17eb5f46cc9d655a4e0c7e82b5
Publikováno v:
Kafkas Universitesi Veteriner Fakültesi Dergisi, Vol 29, Iss 6, Pp 683-688 (2023)
The intravenous lipid emulsion (ILE) therapy is known to alleviate clinical symptoms in cases of bupivacaine-induced cardiac toxicity. However, there is insufficient information regarding histopathological damage. This study aimed to investigate whet
Externí odkaz:
https://doaj.org/article/c36f884a8bfa42aa834857541416bf64
Publikováno v:
Toxins, Vol 16, Iss 8, p 345 (2024)
Chronic kidney disease (CKD) can lead to cardiac dysfunction in a condition known as cardiorenal syndrome (CRS). It is postulated that the accumulation of uremic toxins in the bloodstream, as a consequence of declining kidney function, may contribute
Externí odkaz:
https://doaj.org/article/a87a8fd428a2424497c7c121aaf1411b