Zobrazeno 1 - 10
of 2 393
pro vyhledávání: '"Cardiac repair"'
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Epicardial epithelial-to-mesenchymal transition (EMT) plays a pivotal role in both heart development and injury response and involves dynamic cellular changes that are essential for cardiogenesis and myocardial repair. Specifically, epicardi
Externí odkaz:
https://doaj.org/article/c9b91dc266f54bea9a44467163da4402
Autor:
Victoria J. M. Reid, Wesley K. X. McLoughlin, Kalyani Pandya, Holly Stott, Monika Iškauskienė, Algirdas Šačkus, Judit A. Marti, Dominic Kurian, Thomas M. Wishart, Christophe Lucatelli, Dan Peters, Gillian A. Gray, Andrew H. Baker, David E. Newby, Patrick W. F. Hadoke, Adriana A. S. Tavares, Mark G. MacAskill
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background Cardiac repair and remodeling following myocardial infarction (MI) is a multifactorial process involving pro-reparative inflammation, angiogenesis and fibrosis. Noninvasive imaging using a radiotracer targeting these processes cou
Externí odkaz:
https://doaj.org/article/b3fa38c72c4943ada2374cbe0f7b0709
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
ObjectiveCardiac regenerative medicine has gained significant attention in recent years, and integrins are known to play a critical role in mediating cardiac development and repair, especially after an injury from the myocardial infarction (MI). Give
Externí odkaz:
https://doaj.org/article/25255f3a93b148129b66a9931c7f44c5
Autor:
Antoni Bayes-Genis, Paloma Gastelurrutia, Marta Monguió-Tortajada, Maria Luisa Cámara, Cristina Prat-Vidal, German Cediel, Luciano Rodríguez-Gómez, Albert Teis, Elena Revuelta-López, Gemma Ferrer-Curriu, Santiago Roura, Carolina Gálvez-Montón, Felipe Bisbal, Joaquim Vives, Anna Vilarrodona, Christian Muñoz-Guijosa, Sergi Querol
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105060- (2024)
Summary: Background: In preclinical studies, the use of double allogeneic grafts has shown promising results in promoting tissue revascularization, reducing infarct size, preventing adverse remodelling and fibrosis, and ultimately enhancing cardiac f
Externí odkaz:
https://doaj.org/article/042e3b53b8944b1ca3d48e6cbccb5014
Autor:
Qiaxin Xu, Zeyu Xiao, Qianzhi Yang, Tingting Yu, Xiujiao Deng, Nenghua Chen, Yanyu Huang, Lihong Wang, Jun Guo, Jinghao Wang
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100978- (2024)
A life-threatening illness that poses a serious threat to human health is myocardial infarction. It may result in a significant number of myocardial cells dying, dilated left ventricles, dysfunctional heart function, and ultimately cardiac failure. B
Externí odkaz:
https://doaj.org/article/71ff72684bea472abc9d1c64c008a012
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/f39ff5bc5a3a4192ad2adc4ba1c08ba6
Autor:
Songyang Zheng, Tingting Liu, Mengqi Chen, Fangling Sun, Yihuan Fei, Yanxi Chen, Xin Tian, Zheng Wu, Zixin Zhu, Wenrong Zheng, Yufeng Wang, Wen Wang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Introduction: Acute myocardial infarction (AMI) is characterized by the loss of cardiomyocytes, which impairs cardiac function and eventually leads to heart failure. The induction of cardiomyocyte cell cycle activity provides a new treatment strategy
Externí odkaz:
https://doaj.org/article/0775d6a7cb7f494397295439b3932283
Autor:
Yijun Yang, Jaslyn Johnson, Constantine D. Troupes, Eric A. Feldsott, Lindsay Kraus, Emily Megill, Zilin Bian, Ngefor Asangwe, Tabito Kino, Deborah M. Eaton, Tao Wang, Marcus Wagner, Lena Ma, Christopher Bryan, Markus Wallner, Hajime Kubo, Remus M. Berretta, Mohsin Khan, Hong Wang, Raj Kishore, Steven R. Houser, Sadia Mohsin
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102909- (2023)
Few therapies have produced significant improvement in cardiac structure and function after ischemic cardiac injury (ICI). Our possible explanation is activation of local inflammatory responses negatively impact the cardiac repair process following i
Externí odkaz:
https://doaj.org/article/f68a1e3939344780bdcabe697059e9a3
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Cardiac repair after myocardial infarction (MI) is orchestrated by multiple intrinsic mechanisms in the heart. Identifying cardiac cell heterogeneity and its effect on processes that mediate the ischemic myocardium repair may be key to developing nov
Externí odkaz:
https://doaj.org/article/321b5d11c950436a94c0f039b8557471
Autor:
K. V. Dergilev, Z. I. Tsokolaeva, I. B. Beloglazova, D. O. Traktuev, M. T. Rasulova, E. V. Parfenova
Publikováno v:
Общая реаниматология, Vol 19, Iss 1, Pp 43-49 (2023)
Fundamental research in recent years has allowed us to reassess the molecular and cellular mechanisms of cardiac ontogenesis and its repair after damage. The epicardium, the outer, tightly adjoining layer of the cardiac wall formed by epicardial meso
Externí odkaz:
https://doaj.org/article/45abb70fae994e5d8b006c42550bc745