Zobrazeno 1 - 10
of 3 824
pro vyhledávání: '"Cardiac fibroblasts"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 10605-10621 (2024)
Yijuan Feng,1,* Yan Wang,1,* Li Li,1,* Yan Yang,1 Xiaoqiu Tan,1– 3 Tangting Chen1,2 1Key Laboratory of Medical Electrophysiology of the Ministry of Education, Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of
Externí odkaz:
https://doaj.org/article/81f6743d1ef34071a5c2fed9231a80ed
Autor:
Shujun Yang, Liying Pei, Zijie Huang, Yinsheng Zhong, Jun Li, Yinghui Hong, Huibao Long, Xuxiang Chen, Changqing Zhou, Guanghui Zheng, Chaotao Zeng, Haidong Wu, Tong Wang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Myocardial infarction (MI) leads to enhanced activity of cardiac fibroblasts (CFs) and abnormal deposition of extracellular matrix proteins, resulting in cardiac fibrosis. Tartrate-resistant acid phosphatase 5 (ACP5) has been show
Externí odkaz:
https://doaj.org/article/242d850a424a4905b2a9e4ba2957e691
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35219- (2024)
Diabetic cardiomyopathy (DCM) is a common complication of diabetes, and its pathogenesis remains elusive. Ferroptosis, a process dependent on iron-mediated cell death, plays a crucial role in DCM via disrupted iron metabolism, lipid peroxidation, and
Externí odkaz:
https://doaj.org/article/07ccc63d0f2d468fa59635f1032ceab0
Autor:
Te-An Chen, Brandon B. Zhao, Richard A. Balbin, Sameeksha Sharma, Donggi Ha, Timothy J. Kamp, Yuxiao Zhou, Feng Zhao
Publikováno v:
Matrix Biology Plus, Vol 23, Iss , Pp 100151- (2024)
Extracellular matrix (ECM) fabricated using human induced pluripotent stem cells (hiPSCs)-derived cardiac fibroblasts (hiPSC-CFs) could serve as a completely biological scaffold for an engineered cardiac patch, leveraging the unlimited source and out
Externí odkaz:
https://doaj.org/article/bb95a99955464065987e6c3d37bacac7
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Cardiac fibroblasts (CFs) are activated after initial injury, and then differentiate into myofibroblasts (MFs), which play a pivotal role as the primary mediator cells in pathological remodeling. Sodium butyrate (NaB), being a met
Externí odkaz:
https://doaj.org/article/094c8a546b354fb6a6e2e361ff4eb423
Autor:
Marta Delgado-Arija, Patricia Genovés, Lorena Pérez-Carrillo, Irene González-Torrent, Isaac Giménez-Escamilla, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Cardiac fibroblast activation protein (FAP) has an emerging role in heart failure (HF). A paradoxical reduction in its levels in pathological conditions associated with acute processes has been observed. We aimed to identify FAP c
Externí odkaz:
https://doaj.org/article/7f007be5ed3a4a35954fc3151842bf82
Publikováno v:
All Life, Vol 17, Iss 1 (2024)
Cardiac fibroblasts (CFs) are of vital importance for post-myocardial infarction (MI) remodeling. This study explored the role of Placenta specific 8 (Plac8) in MI on the basis of single-cell RNA-Seq (scRNA-Seq) data (GSE136088) and micro-array data
Externí odkaz:
https://doaj.org/article/3696d0e81f7b4f319961c3b68ae90c5b
Decellularized heart extracellular matrix alleviates activation of hiPSC-derived cardiac fibroblasts
Autor:
Charles M. Kerr, Sophia E. Silver, Yi Sun Choi, Martha E. Floy, Amy D. Bradshaw, Seung-Woo Cho, Sean P. Palecek, Ying Mei
Publikováno v:
Bioactive Materials, Vol 31, Iss , Pp 463-474 (2024)
Human induced pluripotent stem cell derived cardiac fibroblasts (hiPSC-CFs) play a critical role in modeling human cardiovascular diseases in vitro. However, current culture substrates used for hiPSC-CF differentiation and expansion, such as Matrigel
Externí odkaz:
https://doaj.org/article/085242f56f0e407293727c5ae5c5b1f0
Autor:
Cameron Skaggs, Steve Nick, Conner Patricelli, Laura Bond, Kali Woods, Luke Woodbury, Julia Thom Oxford, Xinzhu Pu
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Objective Doxorubicin (DOX) is a highly effective chemotherapeutic used to treat many adult and pediatric cancers. However, its use is limited due to a dose-dependent cardiotoxicity, which can lead to lethal cardiomyopathy. In contrast to th
Externí odkaz:
https://doaj.org/article/46234a302fb44cf7bf5c5723a0ed518c
Publikováno v:
Cells, Vol 13, Iss 16, p 1331 (2024)
Background: The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial to viral entry and can cause cardiac injuries. Toll-like receptor 4 (TLR4) and NOD-, LPR-, and pyrin-domain-containing 3 (NLRP3) inflammasome are
Externí odkaz:
https://doaj.org/article/318e2e00930141e6a98272b8b1bfb89c