Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Carcinogen testing"'
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8977, p 8977 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 8977, p 8977 (2021)
Dysregulation of gap junction intercellular communication (GJIC) is recognized as one of the key hallmarks for identifying non-genotoxic carcinogens (NGTxC). Currently, there is a demand for in vitro assays addressing the gap junction hallmark, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f419a3adb3d16c2e435f6a01d83aa1ba
http://europepmc.org/articles/PMC8396440
http://europepmc.org/articles/PMC8396440
Autor:
David H. Sherr, Stefano Monti, Amy Li, Xiaodong Lu, Nisha S. Sipes, Scott S. Auerbach, Aravind Subramanian, Ted Natoli, Joshua A. Bittker
Publikováno v:
Environmental Health Perspectives
Background: Most chemicals in commerce have not been evaluated for their carcinogenic potential. The de facto gold-standard approach to carcinogen testing adopts the 2-y rodent bioassay, a time-consuming and costly procedure. High-throughput in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb09e8d9df754cf08df1b25ec49c1cc
https://pubmed.ncbi.nlm.nih.gov/30964323
https://pubmed.ncbi.nlm.nih.gov/30964323
Publikováno v:
Regulatory Toxicology and Pharmacology, 3, 71, 601–623
Carbon capture and storage (CCS) technologies are considered vital and economic elements for achieving global CO2 reduction targets, and is currently introduced worldwide (for more information on CCS, consult for example the websites of the Internati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2522c6776482d40ab853395fb212a8
http://resolver.tudelft.nl/uuid:25f306bf-b519-4162-98c8-b2b2fb816d4f
http://resolver.tudelft.nl/uuid:25f306bf-b519-4162-98c8-b2b2fb816d4f
Carbon capture and storage (CCS) technologies are considered vital and economic elements for achieving global CO2 reduction targets, and is currently introduced worldwide (for more information on CCS, consult for example the websites of the Internati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::dfc777e826af3837f6338d0aacc5bad8
http://resolver.tudelft.nl/uuid:25f306bf-b519-4162-98c8-b2b2fb816d4f
http://resolver.tudelft.nl/uuid:25f306bf-b519-4162-98c8-b2b2fb816d4f
Autor:
Renaud, Matthew
Nickel is a widely used metal in industrial and commercial applications, being both workable and highly resistant to corrosion. Certain nickel compounds are known human carcinogens, but not all nickel compounds are equally hazardous. A robust method
Externí odkaz:
http://hdl.handle.net/10214/3632
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 73
In the present study, in vitro cytotoxic and genotoxic effect of copper-zinc alloy nanoparticles (Cu-Zn ANPs) on human lung epithelial cells (BEAS-2B) were investigated. XTT test and clonogenic assay were used to determine cytotoxic effects. Cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4733141a2d50b9f8c235f34351836e
https://pubmed.ncbi.nlm.nih.gov/25116682
https://pubmed.ncbi.nlm.nih.gov/25116682
Autor:
Gary M. Williams
Publikováno v:
Toxicologic Pathology. 25:32-38
For a conventional organic new chemical entity (NCE) being developed as a pharmaceutical, standard regulatory safety assessment studies are required. Early in development, an NCE should undergo a safety/benefit analysis to justify further development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97abd41ad80c9ba4fa867492dcec7eb
https://doi.org/10.1177/019262339702500108
https://doi.org/10.1177/019262339702500108
Autor:
Aart Verhoef, Mirjam M. Schaap, Jan van Benthem, Joost P.M. Melis, Saskia Maas, Harry van Steeg, Mirjam Luijten, Ewoud N. Speksnijder, Raoul V. Kuiper, Daniela C.F. Salvatori, Joke Robinson
Publikováno v:
Toxicology and Applied Pharmacology, 266(2), 289-297
An accurate assessment of the carcinogenic potential of chemicals and pharmaceutical drugs is essential to protect humans and the environment. Therefore, substances are extensively tested before they are marketed to the public. Currently, the rodent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622c4f3c8e20147518bd947d3b106dbf
http://hdl.handle.net/1887/101024
http://hdl.handle.net/1887/101024