Immunogenicity, reactogenicity, and safety of a second booster with BNT162b2 or full-dose mRNA-1273: A randomized VACCELERATE trial in adults aged ≥75 years (EU-COVAT-1-AGED Part B).

Autor: Stemler J; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Yeghiazaryan L; Medical University of Vienna, Center for Medical Data Science, Institute of Medical Statistics, Vienna, Austria., Stephan C; Department of Internal Medicine, Infectious Diseases, University Hospital Frankfurt, Frankfurt am Main, Germany., Mohn KG; Helse Bergen HF, Haukeland University Hospital, Department Internal Medicine, Bergen, Norway; Influenza Centre, Department of Clinical Sciences, University of Bergen, Norway., Carcas-Sansuan AJ; Hospital La Paz, Clinical Pharmacology Service, Institute for Health Research, Universidad Autónoma de Madrid, Faculty of Medicine, Madrid, Spain., Rodriguez ER; Distrito Sanitario Córdoba Guadalquivir, Primary Care Unit, Isla Lanzarote, s/n, Córdoba and Maimonides Biomedical Research Institute of Córdoba(IMIBIC), Reina Sofia University Hospital, University of Córdoba, Córdoba, Spain., Moltó J; Fundació Lluita Contra les Infeccions, Infectious Diseases Department, Hospital Universitari Germans Trias I Pujol, Badalona, Barcelona, Spain; CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain., Mitxeltorena IV; Asociación Instituto BIODONOSTIA, Primary Care Research Unit of Gipuzkoa Integrated Health Organizations, San Sebastián (Gipuzkoa), Spain., Welte T; Medizinische Hochschule Hannover, Klinik für Pneumologie, Hannover, Germany., Zablockienė B; Centre of Infectious Diseases, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania; Lithuania and Clinic of Infectious Diseases and Dermatovenerology, Institute of Clinical Medicine, Vilnius University Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Akova M; Hacettepe University School of Medicine, Department of Infectious Diseases, Ankara, Turkey., Bethe U; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Heringer S; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Salmanton-García J; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Jeck J; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Tischmann L; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Zarrouk M; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany., Cüppers A; University of Cologne, Faculty of Medicine, Clinical Trials Centre Cologne (CTCC Cologne), Cologne, Germany., Biehl LM; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Grothe J; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Mellinghoff SC; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Nacov JA; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Neuhann JM; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Sprute R; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany., Frías-Iniesta J; Hospital La Paz, Clinical Pharmacology Service, Institute for Health Research, Universidad Autónoma de Madrid, Faculty of Medicine, Madrid, Spain., Negi R; Centre for Experimental Pathogen Host Research (CEPHR), School of Medicine, University College Dublin (UCD), Dublin, Ireland., Gaillard C; Centre for Experimental Pathogen Host Research (CEPHR), School of Medicine, University College Dublin (UCD), Dublin, Ireland., Saini G; Centre for Experimental Pathogen Host Research (CEPHR), School of Medicine, University College Dublin (UCD), Dublin, Ireland., León AG; Centre for Experimental Pathogen Host Research (CEPHR), School of Medicine, University College Dublin (UCD), Dublin, Ireland., Mallon PWG; Centre for Experimental Pathogen Host Research (CEPHR), School of Medicine, University College Dublin (UCD), Dublin, Ireland., Lammens C; Laboratory of Medical Microbiology (LMM), Vaccine & Infectious Disease Institute and BioBank Antwerp, University of Antwerp, Antwerpen, Belgium., Hotterbeekx A; Molecular Pathology Group, Laboratory of Cell Biology & Histology (CBH) and Vaccine & Infectious Disease Institute (CBH), Faculty of Medicine, University of Antwerp, Antwerpen, Belgium., Loens K; Laboratory of Medical Microbiology (LMM), Vaccine & Infectious Disease Institute and BioBank Antwerp, University of Antwerp, Antwerpen, Belgium., Malhotra-Kumar S; Laboratory of Medical Microbiology (LMM), Vaccine & Infectious Disease Institute and BioBank Antwerp, University of Antwerp, Antwerpen, Belgium., Goossens H; Laboratory of Medical Microbiology (LMM), Vaccine & Infectious Disease Institute and BioBank Antwerp, University of Antwerp, Antwerpen, Belgium., Kumar-Singh S; Molecular Pathology Group, Laboratory of Cell Biology & Histology (CBH) and Vaccine & Infectious Disease Institute (CBH), Faculty of Medicine, University of Antwerp, Antwerpen, Belgium., König F; Medical University of Vienna, Center for Medical Data Science, Institute of Medical Statistics, Vienna, Austria., Posch M; Medical University of Vienna, Center for Medical Data Science, Institute of Medical Statistics, Vienna, Austria., Koehler P; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany., Cornely OA; University of Cologne, Institute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; University of Cologne, Faculty of Medicine, and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), Cologne, Germany; German Centre for Infection Research (DZIF), Partner Site Bonn Cologne Department, Cologne, Germany; University of Cologne, Faculty of Medicine, Clinical Trials Centre Cologne (CTCC Cologne), Cologne, Germany. Electronic address: oliver.cornely@uk-koeln.de.

Publikováno v: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2024 Sep; Vol. 146, pp. 107161. Date of Electronic Publication: 2024 Jul 09.

Enhancing Public Health Communication Regarding Vaccine Trials: Design and Development of the Pan-European VACCELERATE Toolkit.

Autor: Argyropoulos CD; School of Medicine, European University Cyprus, Nicosia, Cyprus., Leckler J; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Salmanton-García J; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Constantinou M; School of Medicine, European University Cyprus, Nicosia, Cyprus., Alexandrou A; School of Medicine, European University Cyprus, Nicosia, Cyprus., Themistocleous S; School of Medicine, European University Cyprus, Nicosia, Cyprus., Noula E; School of Medicine, European University Cyprus, Nicosia, Cyprus., Shiamakkides G; School of Medicine, European University Cyprus, Nicosia, Cyprus., Nearchou A; School of Medicine, European University Cyprus, Nicosia, Cyprus., Stewart FA; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Albus K; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Koniordou M; Collaborative Center for Clinical Epidemiology and Outcomes Research, Athens, Greece., Kopsidas I; Collaborative Center for Clinical Epidemiology and Outcomes Research, Athens, Greece., Spivak O; Ministry of Health of Israel, Jerusalem, Israel., Hellemans M; VAXINFECTIO, Centre of Evaluation of Vaccination, Faculty of Medicine and Health Science, Universiteit Antwerpen, Antwerp, Belgium., Hendrickx G; VAXINFECTIO, Centre of Evaluation of Vaccination, Faculty of Medicine and Health Science, Universiteit Antwerpen, Antwerp, Belgium., Davis RJ; Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, Verona, Italy., Azzini AM; Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, Verona, Italy., Simon PV; Hospital La Paz Institute for Health Research, Madrid, Spain.; Servicio Madrileño de Salud, Madrid, Spain., Carcas-Sansuan AJ; Hospital La Paz Institute for Health Research, Madrid, Spain.; Servicio Madrileño de Salud, Madrid, Spain., Askling HH; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden., Vene S; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden., Prellezo JB; Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain., Álvarez-Barco E; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin, Dublin, Ireland., Macken AJ; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin, Dublin, Ireland., Di Marzo R; European Vaccine Initiative, Heidelberg, Germany., Luís C; European Vaccine Initiative, Heidelberg, Germany., Olesen OF; European Vaccine Initiative, Heidelberg, Germany., Frias Iniesta JA; Hospital La Paz Institute for Health Research, Madrid, Spain.; Servicio Madrileño de Salud, Madrid, Spain., Barta I; National Koranyi Institute for Pulmonology, Budapest, Hungary., Tóth K; National Koranyi Institute for Pulmonology, Budapest, Hungary., Akova M; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Haceteppe University, Ankara, Turkey., Bonten MMJ; Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands.; Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, Netherlands., Cohen-Kandli M; Ministry of Health of Israel, Jerusalem, Israel., Cox RJ; Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway., Součková L; Masaryk University, Brno, Czech Republic.; University Hospital Brno, Brno, Czech Republic.; Czech Clinical Research Infrastructure Network, Brno, Czech Republic., Husa P; Masaryk University, Brno, Czech Republic.; University Hospital Brno, Brno, Czech Republic.; Czech Clinical Research Infrastructure Network, Brno, Czech Republic., Jancoriene L; Institute of Clinical Medicine, Medical Faculty, Vilnius University, Vilnius, Lithuania.; Vilnius University Hospital Santaros klinikos, Medical Faculty, Vilnius University, Vilnius, Lithuania., Launay O; Institut National de la Santé et de la Recherche Médicale - France Recherche Nord & Sud Sida- HIV Hépatites Maladies Infectieuses Émergentes, Paris, France.; Assistance Publique Hopitaux de Paris, Université Paris Cité, Paris, France., Lundgren J; Centre of Excellence for Health, Immunity and Infections, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Mallon P; Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin, Dublin, Ireland., Armeftis C; School of Medicine, European University Cyprus, Nicosia, Cyprus., Marques L; Centro Hospitalar Universitário do Porto, Porto, Portugal., Naucler P; Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.; Department of Medicine, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden., Ochando J; Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain., Tacconelli E; Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, Verona, Italy., van Damme P; VAXINFECTIO, Centre of Evaluation of Vaccination, Faculty of Medicine and Health Science, Universiteit Antwerpen, Antwerp, Belgium., Zaoutis T; Collaborative Center for Clinical Epidemiology and Outcomes Research, Athens, Greece., Hofstraat S; University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands., Bruijning-Verhagen P; University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands., Zeitlinger M; Medizinische Universität Wien, Vienna, Austria., Cornely OA; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf and Excellence Center for Medical Mycology, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Clinical Trials Centre Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Centre for Infection Research, Partner Site Bonn-Cologne, Cologne, Germany., Pana ZD; School of Medicine, European University Cyprus, Nicosia, Cyprus.

Publikováno v: JMIR public health and surveillance [JMIR Public Health Surveill] 2023 Apr 03; Vol. 9, pp. e44491. Date of Electronic Publication: 2023 Apr 03.

[Risk of thromboembolic events and evaluation of the use of venous thromboembolism prophylaxis in hospitalized medical patients and after discharge].

Autor: Borobia AM; Servicio de Farmacología Clínica, Hospital Universitario La Paz, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, España. a.borobia@gmail.com, Fernández Capitán C, Iniesta Arandia N, García de Paso P, Valero Recio J, Bizighescu M, Carcas Sansuan AJ

Publikováno v: Revista clinica espanola [Rev Clin Esp] 2009 Jan; Vol. 209 (1), pp. 15-20.