Implementing pharmacogenetics in clinical trials: considerations about current methodological, ethical, and regulatory challenges.

Autor: García-García I; Clinical Pharmacology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain.; Departament of Pharmacology and Therapeutics, Facultad de Medicina. Universidad Autónoma de, Madrid, Spain., Seco-Meseguer E; Clinical Pharmacology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain., Borobia AM; Clinical Pharmacology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain.; Departament of Pharmacology and Therapeutics, Facultad de Medicina. Universidad Autónoma de, Madrid, Spain., Carcas-Sansuán AJ; Clinical Pharmacology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain.; Departament of Pharmacology and Therapeutics, Facultad de Medicina. Universidad Autónoma de, Madrid, Spain.

Publikováno v: Expert review of clinical pharmacology [Expert Rev Clin Pharmacol] 2024 Jan; Vol. 17 (1), pp. 1-10. Date of Electronic Publication: 2024 Jan 23.

Health Care Workers' Reasons for Choosing Between Two Different COVID-19 Prophylaxis Trials in an Acute Pandemic Context: Single-Center Questionnaire Study.

Autor: Borobia AM; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., García-García I; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Díaz-García L; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Rodríguez-Mariblanca A; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Martínez de Soto L; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Monserrat Villatoro J; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Seco Meseguer E; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., González JJ; Internal Medicine Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Frías Iniesta J; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Ramírez García E; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Arribas JR; Internal Medicine Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Carcas-Sansuán AJ; Clinical Pharmacology Department, La Paz University Hospital (IdiPAZ), School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.

Publikováno v: Journal of medical Internet research [J Med Internet Res] 2021 Feb 25; Vol. 23 (2), pp. e23441. Date of Electronic Publication: 2021 Feb 25.

Inhaled Methoxyflurane Provides Greater Analgesia and Faster Onset of Action Versus Standard Analgesia in Patients With Trauma Pain: InMEDIATE: A Randomized Controlled Trial in Emergency Departments.

Autor: Borobia AM; Hospital Universitario La Paz, Madrid, Spain; School of Medicine, Universidad Autónoma de Madrid, Hospital La Paz Institute for Health Research, and Spanish Clinical Research Network, Madrid, Spain. Electronic address: alberto.borobia@salud.madrid.org., Collado SG; Hospital Campo Grande, Valladolid, Spain., Cardona CC; Hospital Universitario La Paz, Madrid, Spain; School of Medicine, Universidad Autónoma de Madrid, Hospital La Paz Institute for Health Research, and Spanish Clinical Research Network, Madrid, Spain., Pueyo RC; Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain., Alonso CF; Hospital Clínico San Carlos, Madrid, Spain., Torres IP; Hospital Virgen del Rocío, Seville, Spain., González MC; Hospital General de Alicante, Alicante, Spain., Casal Codesido JR; Hospital el Bierzo, Ponferrada, Spain., Betegón MA; Hospital de Viladecans, Barcelona, Spain., Barcela LA; Hospital Universitario Álvaro Cunqueiro, Vigo, Spain., Andicoechea AO; Hospital Gernika-Lumo, Gernika-Lumo, Spain., Testa AF; Complejo Asistencial de Zamora, Zamora, Spain., Colina JT; Hospital Monográfico Asepeyo de traumatología, cirugía y rehabilitación, Coslada, Spain., Dorribo AC; SUMMA 112, Madrid, Spain., Del Arco Galán C; Hospital Universitario de La Princesa, Madrid, Spain., Martínez Ávila JC; Hospital Universitario La Paz, Madrid, Spain; School of Medicine, Universidad Autónoma de Madrid, Hospital La Paz Institute for Health Research, and Spanish Clinical Research Network, Madrid, Spain., Lugilde ST; Mundipharma Pharmaceuticals S.L., Madrid, Spain., Carcas Sansuán AJ; Hospital Universitario La Paz, Madrid, Spain; School of Medicine, Universidad Autónoma de Madrid, Hospital La Paz Institute for Health Research, and Spanish Clinical Research Network, Madrid, Spain.

Publikováno v: Annals of emergency medicine [Ann Emerg Med] 2020 Mar; Vol. 75 (3), pp. 315-328. Date of Electronic Publication: 2019 Oct 14.

Weight of ABCB1 and POR genes on oral tacrolimus exposure in CYP3A5 nonexpressor pediatric patients with stable kidney transplant.

Autor: Almeida-Paulo GN; Department of Clinical Pharmacology, La Paz University Hospital, School of Medicine, Universidad Autónoma de Madrid, IdiPAZ, Madrid, Spain., Dapía García I; Instituto de Genética Médica y Molecular (INGEMM), La Paz University Hospital, Universidad Autónoma de Madrid, IdiPAZ, Madrid, Spain., Lubomirov R; Department of Clinical Pharmacology, La Paz University Hospital, School of Medicine, Universidad Autónoma de Madrid, IdiPAZ, Madrid, Spain., Borobia AM; Department of Clinical Pharmacology, La Paz University Hospital, School of Medicine, Universidad Autónoma de Madrid, IdiPAZ, Madrid, Spain., Alonso-Sánchez NL; Department of Clinical Pharmacology, La Paz University Hospital, School of Medicine, Universidad Autónoma de Madrid, IdiPAZ, Madrid, Spain., Espinosa L; Department of Pediatric Nephrology, La Paz University Hospital, IdiPAZ, Madrid, Spain., Carcas-Sansuán AJ; Department of Clinical Pharmacology, La Paz University Hospital, School of Medicine, Universidad Autónoma de Madrid, IdiPAZ, Madrid, Spain.

Publikováno v: The pharmacogenomics journal [Pharmacogenomics J] 2018 Jan; Vol. 18 (1), pp. 180-186. Date of Electronic Publication: 2017 Jan 17.

Limited sampling strategies for tacrolimus exposure (AUC0-24) prediction after Prograf(®) and Advagraf(®) administration in children and adolescents with liver or kidney transplants.

Autor: Almeida-Paulo GN; Department of Pharmacology, School of Medicine, Autonomous University of Madrid, Madrid, Spain., Lubomirov R, Alonso-Sanchez NL, Espinosa-Román L, Fernández Camblor C, Díaz C, Muñoz Bartola G, Carcas-Sansuán AJ

Publikováno v: Transplant international : official journal of the European Society for Organ Transplantation [Transpl Int] 2014 Sep; Vol. 27 (9), pp. 939-48. Date of Electronic Publication: 2014 Jun 24.