Zobrazeno 1 - 10 of 134 pro vyhledávání: '"Carboxy terminal sequence"'
1
Gap19, a Cx43 Hemichannel Inhibitor, Acts as a Gating Modifier That Decreases Main State Opening While Increasing Substate Gating
Autor: Nan Wang, Alexander V. Panfilov, Timur V. Nezlobinskii, Alessio Lissoni, Maarten De Smet, Katja Witschas, Luc Leybaert, Nele Vandersickel
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7340, p 7340 (2020)
Int. J. Mol. Sci.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21
Issue 19
Cx43 hemichannels (HCs) are electrically and chemically gated transmembrane pores with low open probability and multiple conductance states, which makes kinetic studies of channel gating in large datasets challenging. Here, we developed open access s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acc65b00aba26523620dc2e788af276
https://pubmed.ncbi.nlm.nih.gov/33027889
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2
Divergent modulation of proteostasis in prostate cancer
Autor: Kırmızıbayrak, Petek Ballar, Gözen, Oğuz, Erzurumlu, Yalçın, Barrio, R, Sutherland, JD, Rodriguez, MS
Proteostasis regulates key cellular processes such as cell proliferation, differentiation, transcription, and apoptosis. The mechanisms by which proteostasis is regulated are crucial and the deterioration of cellular proteostasis has been significant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______9458::9417a90ad155f532ada7c63e64bf5b99
http://hdl.handle.net/11452/30992
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3
Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel
Autor: Wieland Steinchen, Gert Bange, Fabio Lino Gratani, Daniel N. Wilson, Patrick Pausch, Christiane Wolz, Sven-Andreas Freibert, Maha Abdelshahid, Heinrich Schäfer, Kürşad Turgay
Publikováno v: Cell Reports 32 (2020), Nr. 11
Cell Reports
'Cell Reports ', vol: 32, pages: 108157-1-108157-20 (2020)
The stringent response enables metabolic adaptation of bacteria under stress conditions and is governed by RelA/SpoT Homolog (RSH)-type enzymes. Long RSH-type enzymes encompass an N-terminal domain (NTD) harboring the second messenger nucleotide (p)p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c4dcdda91484414b5497672ef776d2
https://www.repo.uni-hannover.de/handle/123456789/12734
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5
Ebola virus disease: An emerging and re-emerging viral threat
Autor: Juan-Manuel Anaya, Carolina Ramírez-Santana, Manuel Rojas, Aftab A Ansari, M. Eric Gershwin, Yeny Acosta-Ampudia, Diana M. Monsalve, Yovana Pacheco
Publikováno v: Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
The genus Ebolavirus from the family Filoviridae is composed of five species including Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and Ebola virus (previously known as Zaire ebolavirus). These viruses have a la
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1ffcd389e6e70cb3e968ef14078c45
https://repository.urosario.edu.co/handle/10336/22246
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6
Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae
Autor: Morlot, Cécile, Straume, Daniel, Peters, Katharina, Hegnar, Olav A., Simon, Nolwenn, Villard, Anne-Marie, Contreras-Martel, Carlos, Leisico, Francisco, Breukink, Eefjan, Gravier-Pelletier, Christine, Le Corre, Laurent, Vollmer, Waldemar, Pietrancosta, Nicolas, Håvarstein, Leiv Sigve, Zapun, André
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
'Nature Communications ', vol: 9, pages: 3180-1-3180-12 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9, pp.3180. ⟨10.1038/s41467-018-05602-w⟩
Nature Communications, 2018, 9, pp.3180. ⟨10.1038/s41467-018-05602-w⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-05602-w⟩
The universality of peptidoglycan in bacteria underlies the broad spectrum of many successful antibiotics. However, in our times of widespread resistance, the diversity of peptidoglycan modifications offers a variety of new antibacterials targets. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6e738dd42a5474741833c74746260284
http://link.springer.com/article/10.1038/s41467-018-05602-w
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7
The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels
Autor: Porro, Saponaro, Gasparri, Bauer, Gross, Pisoni, Abbandonato, Hamacher, Santoro, Thiel, Moroni
Publikováno v: eLife, Vol 8 (2019)
eLife
eLife 8 (2019). doi:10.7554/eLife.49672
info:cnr-pdr/source/autori:Porro, A. and Saponaro, A. and Gasparri, F. and Bauer, D. and Gross, C. and Pisoni, M. and Abbandonato, G. and Hamacher, K. and Santoro, B. and Thiel, G. and Moroni, A./titolo:The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels/doi:10.7554%2FeLife.49672/rivista:eLife/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels control spontaneous electrical activity in heart and brain. Binding of cAMP to the cyclic nucleotide-binding domain (CNBD) facilitates channel opening by relieving a tonic inhibition
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73e2654a65d308a9c30528cb4f5cde3
https://elifesciences.org/articles/49672
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8
A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa
Autor: Joko Priyanto Wibowo, Frank J. Dekker, Matthew Groves, Wim J. Quax, Niels van Oosterwijk, Fernando de Assis Batista
Publikováno v: International Journal of Biological Macromolecules, 146, 212-221. ELSEVIER SCIENCE BV
International journal of biological macromolecules 146, 212-221 (2020). doi:10.1016/j.ijbiomac.2019.12.252
International journal of biological macromolecules 146, 212 - 221 (2020). doi:10.1016/j.ijbiomac.2019.12.252
The biosynthesis of pyoverdine, the major siderophore of Pseudomonas aeruginosa, is a well-organized process involving a discrete number
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a97d788ed4eb4d86b2c9c87c510a75
https://pubmed.ncbi.nlm.nih.gov/31899238
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9
Evaluation of Plasmodium falciparum MSP10 and its development as a serological tool for the Peruvian Amazon region
Autor: Dionicia Gamboa, Renzo Gutierrez-Loli, Katherine Garro, Sandra Morales Ruiz, Jorge Bendezu, Elizabeth Villasis, Pamela Rodriguez, Katherine Torres, Berónica Infante, Manolo Fernández-Díaz
Publikováno v: Malaria Journal
Malaria Journal, Vol 18, Iss 1, Pp 1-13 (2019)
CONCYTEC-Institucional
Consejo Nacional de Ciencia Tecnología e Innovación Tecnológica
instacron:CONCYTEC
Background Different antigens are needed to characterize Plasmodium falciparum infection in terms of seroreactivity and targets for invasion inhibition, in order to guide and identify the proper use of such proteins as tools for the development of se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77aa12664616656a9e8b78d305f086f
https://doi.org/10.1186/s12936-019-2959-8
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10
About the use of 13C-13C NOESY in bioinorganic chemistry
Autor: Veronica Ghini, Paola Turano, Soizic Chevance
Publikováno v: Journal of Inorganic Biochemistry
Journal of Inorganic Biochemistry, Elsevier, 2019, 192, pp.25-32. ⟨10.1016/j.jinorgbio.2018.12.006⟩
Journal of Inorganic Biochemistry, 2019, 192, pp.25-32. ⟨10.1016/j.jinorgbio.2018.12.006⟩
Herein we present examples of the application of the 13C-13C Nuclear Overhauser Effect Spectroscopy (NOESY) experiment to the study of metalloproteins and we critically discuss the advantages and drawbacks of the method as a function of the molecular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a91e6b5be2076a9d9a5a29fbbaa34b
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02043063/file/hal-02043063.pdf
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