Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy

Autor: Kaczanowska, Sabina, Murty, Tara, Alimadadi, Ahmad, Contreras, Cristina F., Duault, Caroline, Subrahmanyam, Priyanka B., Reynolds, Warren, Gutierrez, Norma A., Baskar, Reema, Wu, Catherine J., Michor, Franziska, Altreuter, Jennifer, Liu, Yang, Jhaveri, Aashna, Duong, Vandon, Anbunathan, Hima, Ong, Claire, Zhang, Hua, Moravec, Radim, Yu, Joyce, Biswas, Roshni, Van Nostrand, Stephen, Lindsay, James, Pichavant, Mina, Sotillo, Elena, Bernstein, Donna, Carbonell, Amanda, Derdak, Joanne, Klicka-Skeels, Jacquelyn, Segal, Julia E., Dombi, Eva, Harmon, Stephanie A., Turkbey, Baris, Sahaf, Bita, Bendall, Sean, Maecker, Holden, Highfill, Steven L., Stroncek, David, Glod, John, Merchant, Melinda, Hedrick, Catherine C., Mackall, Crystal L., Ramakrishna, Sneha, Kaplan, Rosandra N.

Publikováno v: In Cancer Cell 8 January 2024 42(1):35-51

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The MEK inhibitor selumetinib reduces spinal neurofibroma burden in patients with NF1 and plexiform neurofibromas.

Autor: Jackson S; Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, Bethesda, Maryland, USA.; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Baker EH; Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Gross AM; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Whitcomb P; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Baldwin A; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Derdak J; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Tibery C; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Desanto J; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Carbonell A; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Yohay K; Departments of Neurology and Pediatrics, NYU Langone Health, New York, New York, USA., O'Sullivan G; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland, USA., Chen AP; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland, USA., Widemann BC; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA., Dombi E; Pediatric Oncology Branch, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland, USA.

Publikováno v: Neuro-oncology advances [Neurooncol Adv] 2020 Aug 08; Vol. 2 (1), pp. vdaa095. Date of Electronic Publication: 2020 Aug 08 (Print Publication: 2020).