Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Carbodiimide hydrochloride"'
Akademický článek
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Autor:
Veronica G. Zinovich, Tatyana S. Khlebnicova, Yu. A. Piven, Alexander V. Baranovsky, R. E. Trifonov, Fedor A. Lakhvich
Publikováno v:
Russian Journal of General Chemistry. 91:1438-1443
2-(Tetrazolylacetyl)cyclohexane-1,3-diones were synthesized via C-acylation of cyclohexane-1,3-diones with tetrazolylacetic acids in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride and N,N-dimethylaminopyridine in acetonit
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 835-847 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 835-847 (2021)
Localized delivery, comparing to systemic drug administration, offers a unique alternative to enhance efficacy, lower dosage, and minimize systemic tissue toxicity by releasing therapeutics locally and specifically to the site of interests. Herein, a
Autor:
Nadine, Zimmann, Petr, Rada, Vojtěch, Žárský, Tamara, Smutná, Kristína, Záhonová, Joel, Dacks, Karel, Harant, Ivan, Hrdý, Jan, Tachezy
Publikováno v:
Molecular & Cellular Proteomics : MCP
The lysosome represents a central degradative compartment of eukaryote cells, yet little is known about the biogenesis and function of this organelle in parasitic protists. Whereas the mannose 6-phosphate (M6P)-dependent system is dominant for lysoso
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 421-432 (2019)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Prodrug nanoassemblies, which can refrain from large excipients, achieve higher drug loading and control drug release, have been placed as the priority in drug delivery system. Reasoning that glutathione (GSH) and reactive oxygen species (ROS) are hi
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 1, Pp 144-156 (2019)
Acta Pharmaceutica Sinica B, Vol 9, Iss 1, Pp 144-156 (2019)
Natural product evodiamine and its derivatives represent a promising class of multi-target antitumor agents. However, the clinical development of these compounds has been hampered by a poor understanding of their antitumor mechanisms. To tackle this
Autor:
Shenwei Ding, Wang Xudong, Chen Jianshu, Yu Yi, Zhang Yanlu, Jianming Hu, Jianfeng Mei, Guoqing Ying
Publikováno v:
Journal of pharmaceutical analysis. 12(3)
Due to the complexity of bioactive ingredients in biological samples, the screening of target proteins is a complex process. Herein, a feasible strategy for directed protein immobilization on silica magnetic beads for ligand fishing based on SpyTag/S
Akademický článek
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Autor:
Hui Shi, Delong Wang
Publikováno v:
Molecules, Vol 25, Iss 2131, p 2131 (2020)
Molecules
Molecules
The reaction of isodehydracetic acid with amines was serendipitously found to afford β-enaminones in the presence of the coupling agent 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC). Under the optimal reaction condition, 23 exam
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-17 (2018)
Graphene’s unique physical structure, as well as its chemical and electrical properties, make it ideal for use in sensor technologies. In the past years, novel sensing platforms have been proposed with pristine and modified graphene with nanopartic