Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy

Autor: Kerns, Sarah L, Fachal, Laura, Dorling, Leila, Barnett, Gillian C, Baran, Andrea, Peterson, Derick R, Hollenberg, Michelle, Hao, Ke, Narzo, Antonio Di, Ahsen, Mehmet Eren, Pandey, Gaurav, Bentzen, Søren M, Janelsins, Michelle, Elliott, Rebecca M, Pharoah, Paul D P, Burnet, Neil G, Dearnaley, David P, Gulliford, Sarah L, Hall, Emma, Sydes, Matthew R, Aguado-Barrera, Miguel E, Gómez-Caamaño, Antonio, Carballo, Ana M, Peleteiro, Paula, Lobato-Busto, Ramón, Stock, Richard, Stone, Nelson N, Ostrer, Harry, Usmani, Nawaid, Singhal, Sandeep, Tsuji, Hiroshi, Imai, Takashi, Saito, Shiro, Eeles, Rosalind, DeRuyck, Kim, Parliament, Matthew, Dunning, Alison M, Vega, Ana, Rosenstein, Barry S, West, Catharine M L

Publikováno v: JNCI Journal of the National Cancer Institute

Background A total of 10%–20% of patients develop long-term toxicity following radiotherapy for prostate cancer. Identification of common genetic variants associated with susceptibility to radiotoxicity might improve risk prediction and inform func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::27564910ae77cf1bc048420fb38f30ad
https://www.repository.cam.ac.uk/handle/1810/293486

Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

Autor: Kerns, Sarah L, Dorling, Leila, Fachal, Laura, Bentzen, Søren, Pharoah, Paul D P, Barnes, Daniel R, Gómez-Caamaño, Antonio, Carballo, Ana M, Dearnaley, David P, Peleteiro, Paula, Gulliford, Sarah L, Hall, Emma, Michailidou, Kyriaki, Carracedo, Ángel, Sia, Michael, Stock, Richard, Stone, Nelson N, Sydes, Matthew R, Tyrer, Jonathan P, Ahmed, Shahana, Parliament, Matthew, Ostrer, Harry, Rosenstein, Barry S, Vega, Ana, Burnet, Neil G, Dunning, Alison M, Barnett, Gillian C, West, Catharine M L

Publikováno v: EBioMedicine, Vol 10, Iss C, Pp 150-163 (2016)
EBioMedicine
Kerns, S L, Dorling, L, Fachal, L, Bentzen, S, Pharoah, P D P, Barnes, D R, Gómez-Caamaño, A, Carballo, A M, Dearnaley, D P, Peleteiro, P, Gulliford, S L, Hall, E, Michailidou, K, Carracedo, Á, Sia, M, Stock, R, Stone, N N, Sydes, M R, Tyrer, J P, Ahmed, S, Parliament, M, Ostrer, H, Rosenstein, B S, Vega, A, Burnet, N G, Dunning, A M, Barnett, G C, West, C M L & Radiogenomics Consortium 2016, ' Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer ', EBioMedicine, vol. 10, pp. 150-163 . https://doi.org/10.1016/j.ebiom.2016.07.022

Nearly 50% of cancer patients undergo radiotherapy. Late radiotherapy toxicity affects quality-of-life in long-term cancer survivors and risk of side-effects in a minority limits doses prescribed to the majority of patients. Development of a test pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::32e2b9671f124ffa23b89812d94a423f

Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy

Autor: Kerns, Sarah L, Fachal, Laura, Dorling, Leila, Barnett, Gillian C, Baran, Andrea, Peterson, Derick R, Hollenberg, Michelle, Hao, Ke, Narzo, Antonio Di, Ahsen, Mehmet Eren, Pandey, Gaurav, Bentzen, Søren M, Janelsins, Michelle, Elliott, Rebecca M, Pharoah, Paul DP, Burnet, Neil G, Dearnaley, David P, Gulliford, Sarah L, Hall, Emma, Sydes, Matthew R, Aguado-Barrera, Miguel E, Gómez-Caamaño, Antonio, Carballo, Ana M, Peleteiro, Paula, Lobato-Busto, Ramón, Stock, Richard, Stone, Nelson N, Ostrer, Harry, Usmani, Nawaid, Singhal, Sandeep, Tsuji, Hiroshi, Imai, Takashi, Saito, Shiro, Eeles, Rosalind, DeRuyck, Kim, Parliament, Matthew, Dunning, Alison M, Vega, Ana, Rosenstein, Barry S, West, Catharine ML

BACKGROUND: A total of 10%-20% of patients develop long-term toxicity following radiotherapy for prostate cancer. Identification of common genetic variants associated with susceptibility to radiotoxicity might improve risk prediction and inform funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a3896397e66ea35a68c292942635818

A microporosity study of Villamayor Sandstone (Salamanca, Spain)

Autor: Arco, Margarita Del, Carballo, Ana M., Holgado, María J., Martín, Cristina, Rives, V.

Publikováno v: In Applied Clay Science 1987 2(4):375-383