Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Caralyn E. Flack"'
Autor:
Jeffrey S. Kavanaugh, Caralyn E. Flack, Jessica Lister, Erica B. Ricker, Carolyn B. Ibberson, Christian Jenul, Derek E. Moormeier, Elizabeth A. Delmain, Kenneth W. Bayles, Alexander R. Horswill
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial biofilms. Using Staphylococcus aureus as a model pathogen, we identified proteins with
Externí odkaz:
https://doaj.org/article/a8e208da8e384b019ca1c75e6293f2c3
Autor:
Caralyn E. Flack, John S. Parkinson
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The chemotaxis machinery of Escherichia coli has served as a model for exploring the molecular signaling mechanisms of transmembrane chemoreceptors known as methyl-accepting chemotaxis proteins (MCPs). Yet, fundamental questions about signal transmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6fe40e77ae896d676b90a17ac62df29
https://doi.org/10.1073/pnas.2204161119
https://doi.org/10.1073/pnas.2204161119
Autor:
Tyler K. Nygaard, Jennifer G. Dankoff, Shaun R. Brinsmade, Brock Cone, Madison M. Collins, Tyler J. Evans, Jovanka M. Voyich, Willis Pullman, Owen Burroughs, Ranjan K. Behera, Caralyn E. Flack, Kyler B. Pallister, Fermin E. Guerra
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Staphylococcus aureus (S. aureus) causes a range of diseases ranging from superficial skin and soft-tissue infections to invasive and life-threatening conditions (Klevens et al., 2007; Kobayashi et al., 2015). S. aureus utilizes the Sae sensory syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d321c7aa8d545fce05de6bb04636f53c
https://www.frontiersin.org/article/10.3389/fmicb.2020.00561/full
https://www.frontiersin.org/article/10.3389/fmicb.2020.00561/full
Autor:
Jessica L. Lister, Alexander R. Horswill, Carolyn B. Ibberson, Erica B. Ricker, Caralyn E. Flack, Derek E. Moormeier, Kenneth W. Bayles, Elizabeth A. Delmain, Christian Jenul, Jeffrey S. Kavanaugh
Publikováno v:
mBio
mBio, Vol 10, Iss 3, p e01137-19 (2019)
mBio, Vol 10, Iss 3 (2019)
mBio, Vol 10, Iss 3, p e01137-19 (2019)
mBio, Vol 10, Iss 3 (2019)
Many bacteria are capable of forming biofilms encased in a matrix of self-produced extracellular polymeric substances (EPS) that protects them from chemotherapies and the host defenses. As a result of these inherent resistance mechanisms, bacterial b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9665122c0e6c56960931973ee5f85df0
https://doi.org/10.1128/mbio.01137-19
https://doi.org/10.1128/mbio.01137-19
Autor:
John S. Parkinson, Caralyn E. Flack
Environmental awareness is an essential attribute for all organisms. The chemotaxis system of Escherichia coli provides a powerful experimental model for the investigation of stimulus detection and signaling mechanisms at the molecular level. These b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c318dfb2818e06a1da6579745243856
https://europepmc.org/articles/PMC5899470/
https://europepmc.org/articles/PMC5899470/
Autor:
Amanda L. Garner, Gunnar F. Kaufmann, Kim D. Janda, Alexander R. Horswill, Jenny M. Mee, Robert N. Kirchdoerfer, Caralyn E. Flack, Ian A. Wilson
Publikováno v:
Journal of Biological Chemistry. 286:17351-17358
In the postantibiotic era, available treatment options for severe bacterial infections caused by methicillin-resistant Staphylococcus aureus have become limited. Therefore, new and innovative approaches are needed to combat such life-threatening infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f9d6fb806aef86f63b01912dd5a808
https://doi.org/10.1074/jbc.m111.231258
https://doi.org/10.1074/jbc.m111.231258
Autor:
Kyler B. Pallister, Cheryl L. Malone, Caralyn E. Flack, Jovanka M. Voyich, Alexander R. Horswill, Delisha D. Meishery, Oliwia W. Zurek
Publikováno v:
Proceedings of the National Academy of Sciences. 111
Two-component systems (TCSs) are highly conserved across bacteria and are used to rapidly sense and respond to changing environmental conditions. The human pathogen Staphylococcus aureus uses the S. aureus exoprotein expression (sae) TCS to sense hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175103bdc8ce3d0dbce6c7d7faa14577
https://doi.org/10.1073/pnas.1322125111
https://doi.org/10.1073/pnas.1322125111
Autor:
Kyler B. Pallister, Jeffrey S. Kavanaugh, Oliwia W. Zurek, Robert L. Watkins, Caralyn E. Flack, Barry N. Kreiswirth, Laynez W. Ackermann, Michael E. Olson, Jovanka M. Voyich, Tyler K. Nygaard, Alexander R. Horswill, Shannon Griffith, Megan R. Kiedrowski
Several prominent bacterial pathogens secrete nuclease (Nuc) enzymes that have an important role in combating the host immune response. Early studies of Staphylococcus aureus Nuc attributed its regulation to the agr quorum-sensing system. However, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caea6e882aa07a6f3a7f084f969bed16
https://europepmc.org/articles/PMC3639593/
https://europepmc.org/articles/PMC3639593/
Publikováno v:
Chemical reviews. 111(1)
Gram-negative and Gram-positive bacteria have evolved elaborate machinery to biosynthesize and respond to diverse small-molecule signals. As bacteria grow, these signals accumulate in the extracellular environment until a particular concentration is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd8dc4e0c6d55ed86475b17bd5970f2
https://pubmed.ncbi.nlm.nih.gov/21174435
https://pubmed.ncbi.nlm.nih.gov/21174435