Výsledky vyhledávání - "Caraballo Otero, Juan Manuel"

High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle

Autor: Caraballo Otero, Juan Manuel, Acosta Cobacho, Juan Carlos, Cortés Vázquez, Miguel Ángel, Albajar Molera, Marta, Gómez Casares, María Teresa, Batllé López, Ana, Cuadrado, María Ángeles, Onaindia Pérez, Arantza, Bretones Sánchez, Gabriel, Llorca Díaz, Francisco Javier, Piris Pinilla, Miguel Ángel, Colomer Pujol, Dolors, León Serrano, Javier

Publikováno v: Oncotarget. 2014 Jul 15;5(13):4694-708
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

Myc (c-Myc) counteracts p27 effects, and low p27 usually correlates with high Myc expression in human cancer. However there is no information on the co-expression of both genes in chronic lymphocytic leukemia (CLL). We found a lack of correlation bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b5d5d12420eba0344b8e7e98bc373e02
http://hdl.handle.net/10902/5080

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Myc-p27 expression and interactions in chronic lymphocytic leukemia and in myeloid cells differentiation

Autor: Caraballo Otero, Juan Manuel

Publikováno v: UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

We studied expression levels of cell cycle inhibitor p27 and Myc (an oncogenic transcription factor) in more than 100 chronic lymphocytic leukemia (CLL) patients. p27 and Myc levels were inversely correlated. Thus, the ratio between p27 (overexpresse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8f1c9bb18f774444a1c86e3f5bceddb0
http://hdl.handle.net/10902/2654

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