Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cara L Griffith"'
Publikováno v:
Glycobiology, 27, 1, pp. 87-98
Glycobiology, 27, 87-98
Glycobiology, 27, 87-98
Cryptococcus neoformans, an opportunistic fungal pathogen, produces a glycan capsule to evade the immune system during infection. This definitive virulence factor is composed mainly of complex polysaccharides, which are made in the secretory pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6243f0cba715773f434d24c5365372
https://hdl.handle.net/2066/167693
https://hdl.handle.net/2066/167693
Loss of cell wall alpha(1-3) glucan affects Cryptococcus neoformans from ultrastructure to virulence
Autor:
Myoung-Ju Kim, Julia Breger, Masako Osumi, Hong Liu, Julianne A. Sefko, Anne Beauvais, Sarah Yang, Cara L. Griffith, Colleen Skau, Eleftherios Mylonakis, Jean-Paul Latgé, Aki Yoneda, Indrani Bose, Tamara L. Doering, Amy J. Reese
Publikováno v:
Molecular Microbiology. 63:1385-1398
Yeast cell walls are critical for maintaining cell integrity, particularly in the face of challenges such as growth in mammalian hosts. The pathogenic fungus Cryptococcus neoformans additionally anchors its polysaccharide capsule to the cell surface
Publikováno v:
Journal of Biological Chemistry. 279:51669-51676
Cryptococcus neoformans is a pathogenic fungus surrounded by an elaborate polysaccharide capsule that is strictly required for its virulence in humans and other mammals. Nearly half of the sugar residues in the capsule are derived from UDP-glucuronic
Autor:
Hong Liu, Cara L. Griffith, Ezekiel J. Maier, Matthew Williams, Michael L. Skowyra, Zhuo Wang, Tamara L. Doering, Michael R. Brent, Stacey R. Gish, Nichole D. Salinas
Publikováno v:
Eukaryotic cell. 13(6)
Cryptococcus neoformans is an opportunistic yeast responsible for lethal meningoencephalitis in humans. This pathogen elaborates a polysaccharide capsule, which is its major virulence factor. Mannose constitutes over one-half of the capsule mass and
Autor:
Stephen M. Beverley, Tamara L. Doering, Michael R. McNeil, Victoria Jones, Katherine Owens, Melissa Showalter, Cara L. Griffith
Publikováno v:
Eukaryotic cell. 4(6)
Galactofuranose (Gal f ) is a novel sugar absent in mammals but present in a variety of pathogenic microbes, often within glycoconjugates that play critical roles in cell surface formation and the infectious cycle. In prokaryotes, Gal f is synthesize
Publikováno v:
The Biochemical journal. 381(Pt 1)
UDP-glucose dehydrogenase catalyses the conversion of UDP-glucose into UDP-GlcA, a critical precursor for glycan synthesis across evolution. We have cloned the gene encoding this important enzyme from the opportunistic pathogen Cryptococcus neoforman
Autor:
Joseph L. Roti Roti, Douglas R. Spitz, Robert P. Vanderwaal, Cara L. Griffith, Ryuji Higashikubo
Publikováno v:
Journal of cellular biochemistry. 85(4)
DNA–nuclear matrix (NM) anchoring plays a critical role in the organization of DNA within the nucleus and in functional access to DNA for transcription, replication, and DNA repair. The cellular response to oxidative stress involves both gene expre
Autor:
Rico A. Caldo, Paul J. Loida, Abha Khandelwal, Bonnie R. Brayton, Rebecca L. Thompson, Lesley R. Murphy, J. Philip Taylor, Radha G. Mohanty, Stephanie L. Back, Sivalinganna Manjunath, Qing Huai, Matthew J. Lingard, Matt Foster, Dongming Jiang, Jean-Louis K. Kouadio, Saritha V. Kuriakose, Amanda J. Burek, Josh D. Kinser, Thomas G. Ruff, Huachun Larue, Shiv B. Tiwari, Mingya G. Huang, William J. Wingbermuehle, Luc Adam, Marie E. Petracek, James A. Morrell, Rosemarie Kuehn, Cara L Griffith, Peter P. Repetti, Robert A. Creelman, Rodrigo G. Sala, Elena A. Rice, T. Lynne Reuber, Jeffrey Ahrens, Anagha M. Sant, Kyle Skottke, Todd E. Ziegler
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e94238 (2014)
PLoS ONE, Vol 9, Iss 4, p e94238 (2014)
ATHB17 (AT2G01430) is an Arabidopsis gene encoding a member of the α-subclass of the homeodomain leucine zipper class II (HD-Zip II) family of transcription factors. The ATHB17 monomer contains four domains common to all class II HD-Zip proteins: a
UDP-xylose is a sugar donor required for the synthesis of diverse and important glycan structures in animals, plants, fungi, and bacteria. Xylose-containing glycans are particularly abundant in plants and in the polysaccharide capsule that is the maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7e887738e03a481beeaf3b9b441645
https://europepmc.org/articles/PMC59757/
https://europepmc.org/articles/PMC59757/
Autor:
Robert P. Vanderwaal, Michael J. Borrelli, J. L. Roti Roti, Cara L. Griffith, William D. Wright
Publikováno v:
Journal of cellular physiology. 187(2)
The mechanism by which a cell protects itself from the lethal effects of heat shock and other stress-inducing agents is the subject of much research. We have investigated the relationship between heat-induced damage to DNA replication machinery and t