Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Cara Haymaker"'
Autor:
Shan He, Matthew M. Gubin, Hind Rafei, Rafet Basar, Merve Dede, Xianli Jiang, Qingnan Liang, Yukun Tan, Kunhee Kim, Maura L. Gillison, Katayoun Rezvani, Weiyi Peng, Cara Haymaker, Sharia Hernandez, Luisa M. Solis, Vakul Mohanty, Ken Chen
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110096- (2024)
Summary: Recent developments in immunotherapy, including immune checkpoint blockade (ICB) and adoptive cell therapy (ACT), have encountered challenges such as immune-related adverse events and resistance, especially in solid tumors. To advance the fi
Externí odkaz:
https://doaj.org/article/857a54432adf43e68098a98661073bd8
Autor:
Gayatri Kumar, Renganayaki Krishna Pandurengan, Edwin Roger Parra, Kasthuri Kannan, Cara Haymaker
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Spatial modelling methods have gained prominence with developments in high throughput imaging platforms. Multiplex immunofluorescence (mIF) provides the scope to examine interactions between tumor and immune compartment at single cell resolution usin
Externí odkaz:
https://doaj.org/article/37021d317a1a430da88180de80092f3d
Autor:
Jianhua Zhang, Hong Chen, Cara Haymaker, Elad Sharon, Razelle Kurzrock, Young Kwang Chae, Jiexin Zhang, Jack Lee, Jianjun Zhang, Ignacio Wistuba, Megan Othus, Sarah Fenton, Cristina Rodriguez, Adedayo Onitilo, Ahmad Mattour, Igor Rybkin, Christine McLeod, Helen Chen, Christopher Ryan, Melissa Plets, Charles Blanke, Gheath Al-Atrash, Rajyalakshmi Luthra, Hye Sung Kim, Dzifa Y Duose, Liam Il-Young Chung, Sandip P Patel, Yichen Lu, Edwin Roger Parra, Lorena Isabel Gomez Bolanos, Caddie Laberiano Fernandez, Luisa Solis Soto, Ganiraju Manyam, Gabby Lopez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/07c970496cd1451ea6e94d54b2c67cd6
Autor:
Cara Haymaker, Aung Naing, Minal Barve, Marya Chaney, Se Hwan Yang, Siyoung Lee, Byung Ha Lee, Sara Ferrando-Martinez, Hirva Mamdani, Richard D Kim, Meredith Pelster, Mohamed Derbala, Jack Goon, Samuel Darko, Julie Murphy, Lauren Gorelik, Allison Bierly
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/3834b1df978a4a97b72c5c4dae0c35d4
Autor:
David Geller, Ashley Moody, Richard Carvajal, Cara Haymaker, Sunil Reddy, Jose Lutzky, Shailender Bhatia, Diwakar Davar, Bartosz Chmielowski, Theresa Medina, Eric Wehrenberg-Klee, Marlana Orloff, Rahul Sheth, Sapna P Patel, Robert Knight, Jason Laporte, Prajna Guha, Bryan Cox, Steven Katz, Paula Novelli, Joshua D Kuban, Ann-Marie Hulstine, Kamaneh Montazeri, Shaheer A Khan, Lindsay Thornton, Anthony Lucci, Vanessa Sarli, Salyna Meas, Chandra C Ghosh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/4699634df0af46c0a34fa5697092f712
Immune cellular patterns of distribution affect outcomes of patients with non-small cell lung cancer
Autor:
Edwin Roger Parra, Jiexin Zhang, Mei Jiang, Auriole Tamegnon, Renganayaki Krishna Pandurengan, Carmen Behrens, Luisa Solis, Cara Haymaker, John Victor Heymach, Cesar Moran, Jack J. Lee, Don Gibbons, Ignacio Ivan Wistuba
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Studying the cellular geographic distribution in non-small cell lung cancer is essential to understand the roles of cell populations in this type of tumor. In this study, we characterize the spatial cellular distribution of immune cell popul
Externí odkaz:
https://doaj.org/article/37d883b1b0724befa4395d0a5874aeca
Autor:
Anurag Purushothaman, Jacqueline Oliva-Ramírez, Warapen Treekitkarnmongkol, Deivendran Sankaran, Mark W. Hurd, Nagireddy Putluri, Anirban Maitra, Cara Haymaker, Subrata Sen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14652 (2023)
Pancreatic ductal adenocarcinoma (PDAC) cells display extensive crosstalk with their surrounding environment to regulate tumor growth, immune evasion, and metastasis. Recent advances have attributed many of these interactions to intercellular communi
Externí odkaz:
https://doaj.org/article/f424909b8eae4dcea223eeb79c3530ef
Autor:
Tina Cascone, Annikka Weissferdt, Myrna C. B. Godoy, William N. William, Cheuk H. Leung, Heather Y. Lin, Sreyashi Basu, Shalini S. Yadav, Apar Pataer, Kyle G. Mitchell, Md Abdul Wadud Khan, Yushu Shi, Cara Haymaker, Luisa M. Solis, Edwin R. Parra, Humam Kadara, Ignacio I. Wistuba, Padmanee Sharma, James P. Allison, Nadim J. Ajami, Jennifer A. Wargo, Robert R. Jenq, Don L. Gibbons, J. Jack Lee, Stephen G. Swisher, Ara A. Vaporciyan, John V. Heymach, Boris Sepesi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Granulomatous/sarcoid-like lesions have been reported in patients treated with immune checkpoint inhibitors (ICIs). Here the authors report the occurrence of “nodal immune flare”, an apparent radiological cancer progression in the nodes character
Externí odkaz:
https://doaj.org/article/02f55269e7f9462fb8c8389a4b130848
Autor:
Hitoshi Dejima, Xin Hu, Runzhe Chen, Jiexin Zhang, Junya Fujimoto, Edwin R. Parra, Cara Haymaker, Shawna M. Hubert, Dzifa Duose, Luisa M. Solis, Dan Su, Junya Fukuoka, Kazuhiro Tabata, Hoa H. N. Pham, Nicholas Mcgranahan, Baili Zhang, Jie Ye, Lisha Ying, Latasha Little, Curtis Gumbs, Chi-Wan Chow, Marcos Roberto Estecio, Myrna C. B. Godoy, Mara B. Antonoff, Boris Sepesi, Harvey I. Pass, Carmen Behrens, Jianhua Zhang, Ara A. Vaporciyan, John V. Heymach, Paul Scheet, J. Jack Lee, Jia Wu, P. Andrew Futreal, Alexandre Reuben, Humam Kadara, Ignacio I. Wistuba, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The evolution of immune landscape in lung adenocarcinoma (ADC) is largely unknown. Here the authors use a cohort of resected invasive lung ADC and its precursors and show a gradual increase of immunosuppression and decrease of anti-tumor response ass
Externí odkaz:
https://doaj.org/article/90f6cd0b92e742178a0fc4cce008b8e0
Autor:
Amber Hickman, Joost Koetsier, Trevin Kurtanich, Michael C. Nielsen, Glenn Winn, Yunfei Wang, Salah-Eddine Bentebibel, Leilei Shi, Simone Punt, Leila Williams, Cara Haymaker, Charles B. Chesson, Faisal Fa’ak, Ana L. Dominguez, Richard Jones, Isere Kuiatse, Amy R. Caivano, Sayadeth Khounlo, Navin D. Warier, Upendra Marathi, Robert V. Market, Ronald J. Biediger, John W. Craft Jr., Patrick Hwu, Michael A. Davies, Darren G. Woodside, Peter Vanderslice, Adi Diab, Willem W. Overwijk, Yared Hailemichael
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
The inability of CD8+ effector T cells (Teffs) to reach tumor cells is an important aspect of tumor resistance to cancer immunotherapy. The recruitment of these cells to the tumor microenvironment (TME) is regulated by integrins, a family of adhesion
Externí odkaz:
https://doaj.org/article/fa40e9308828487fa0c01f7b477bb940