Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cara Fiorino"'
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104498 (2014)
Macrophages are generated through the differentiation of monocytes in tissues and they have important functions in innate and adaptive immunity. In addition to their roles as phagocytes, macrophages can be further differentiated, in the presence of r
Externí odkaz:
https://doaj.org/article/969b88e3c57641c2b2c68cc412e50d84
Publikováno v:
Molecular Biology of the Cell. 33
Osteoclasts are highly specialized, multinucleated cells responsible for the selective resorption of the dense, calcified bone matrix. Microtubules (MTs) contribute to the polarization and trafficking events involved in bone resorption by osteoclasts
Publikováno v:
Journal of cell science. 133(12)
The mechanism and role of transient F-actin recruitment, or F-actin 'flashes', on phagosomes remains enigmatic. Here we provide a comprehensive characterization of F-actin flashing dynamics on phagosomes, including receptor and signaling involvement.
Autor:
Sofia Pustylnik, Rosa da Silva, Cara Fiorino, Tanya Zappitelli, Jane E. Aubin, Noushin Nabavi, Rene E. Harrison
Publikováno v:
Journal of Biological Chemistry. 288:22096-22110
Osteoblasts are differentiated mesenchymal cells that function as the major bone-producing cells of the body. Differentiation cues including ascorbic acid (AA) stimulation provoke intracellular changes in osteoblasts leading to the synthesis of the o
Autor:
Cara Fiorino, Rene E. Harrison
Publikováno v:
Bone. 86
E-cadherin, a protein responsible for intercellular adhesion between epithelial cells, is also expressed in the monocyte/macrophage lineage. In this study we have explored the involvement of E-cadherin during receptor activator of nuclear factor-κB
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 8, p e104498 (2014)
PLoS ONE, Vol 9, Iss 8, p e104498 (2014)
Macrophages are generated through the differentiation of monocytes in tissues and they have important functions in innate and adaptive immunity. In addition to their roles as phagocytes, macrophages can be further differentiated, in the presence of r
Autor:
Artur J. de Brum-Fernandes, Svetlana V. Komarova, Marianne Durand, Keying Li, S. Jeffrey Dixon, Rene E. Harrison, Marcin J. Mizianty, Ajay Bhargava, Noushin Nabavi, Osama Maria, Morris F. Manolson, Sonia Haroun, Cara Fiorino, Maria de Fatima Lucena-Fernandes, Lukasz Kurgan, Stephen M. Sims, Diana P. Trebec-Reynolds, Gilles Boire
Publikováno v:
Arthritis and rheumatism. 65(1)
Objective To compare the osteoclastogenic capacity of peripheral blood mononuclear cells (PBMCs) from patients with osteoarthritis (OA) to that of PBMCs from self-reported normal individuals. Methods PBMCs from 140 patients with OA and 45 healthy don