Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cara E Moravec"'
Publikováno v:
J Vis Exp
Early development depends on a pool of maternal factors incorporated into the mature oocyte during oogenesis that perform all cellular functions necessary for development until zygotic genome activation. Typically, genetic targeting of these maternal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a212bbefa3a677a1c65a3b10f3c12e
https://pubmed.ncbi.nlm.nih.gov/35001909
https://pubmed.ncbi.nlm.nih.gov/35001909
We show that the zebrafish maternal-effect mutation too much information (tmi) corresponds to zebrafish prc1-like (prc1l), which encodes a member of the MAP65/Ase1/PRC1family of microtubule-associated proteins. Embryos from tmi/prc1l homozygous mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e42178cb0efebcbca98547ff2ffdbd6
https://doi.org/10.1101/2021.06.10.447958
https://doi.org/10.1101/2021.06.10.447958
Publikováno v:
Development
In animals, early development is dependent on a pool of maternal factors, both RNA and proteins, which are required for basic cellular process and cell differentiation until zygotic genome activation. The role of a majority of these maternally expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d6f072c98b39acaf551c143fdee78a
https://doi.org/10.1101/2021.02.19.432057
https://doi.org/10.1101/2021.02.19.432057
Autor:
Cara E, Moravec, Francisco, Pelegri
Publikováno v:
Current topics in developmental biology. 140
The transmission of genetic information from one generation to another is crucial for survival of animal species. This is accomplished by the induction of primordial germ cells (PGCs) that will eventually establish the germline. In some animals the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c624d4e18312e6ba3e540392ef0014ca
https://pubmed.ncbi.nlm.nih.gov/32591073
https://pubmed.ncbi.nlm.nih.gov/32591073
Autor:
Francisco Pelegri, Cara E Moravec
The transmission of genetic information from one generation to another is crucial for survival of animal species. This is accomplished by the induction of primordial germ cells (PGCs) that will eventually establish the germline. In some animals the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c10da54fa95fa5332468a010dc69f86
https://doi.org/10.1016/bs.ctdb.2020.02.001
https://doi.org/10.1016/bs.ctdb.2020.02.001
Autor:
Hakeem Yousef, Camillia M. Monestime, Benjamin L. Martin, Howard I. Sirotkin, Ryan Salerno-Eichenholz, Brian A. Kinney, Cara E. Moravec
Publikováno v:
Developmental Dynamics. 246:946-955
Background The transcriptional co-repressor Sin3 is highly conserved from yeast to vertebrates and has multiple roles controlling cell fate, cell cycle progression, and senescence programming. Sin3 proteins recruit histone deacetylases and other chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1506ce087f12a0cdb871a23b1f6a0caa
https://doi.org/10.1002/dvdy.24581
https://doi.org/10.1002/dvdy.24581
Autor:
Cara E, Moravec, Francisco J, Pelegri
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1920
The ability to create targeted mutations in specific genes, and therefore a loss-of-function condition, provides essential information about their endogenous functions during development and homeostasis. The discovery that CRISPR-Cas9 can target spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93839a97650b47f28a960ba3f6427d06
https://pubmed.ncbi.nlm.nih.gov/30737704
https://pubmed.ncbi.nlm.nih.gov/30737704
Autor:
Cara E Moravec, Francisco Pelegri
Publikováno v:
Methods in Molecular Biology ISBN: 9781493990085
The ability to create targeted mutations in specific genes, and therefore a loss-of-function condition, provides essential information about their endogenous functions during development and homeostasis. The discovery that CRISPR-Cas9 can target spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40dcd93015a476fd1269454d2e58debc
https://doi.org/10.1007/978-1-4939-9009-2_23
https://doi.org/10.1007/978-1-4939-9009-2_23
Publikováno v:
The Journal of Neuroscience. 36:9407-9419
During embryonic development, regulation of gene expression is key to creating the many subtypes of cells that an organism needs throughout its lifetime. Recent work has shown that maternal genetics and environmental factors have lifelong consequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c4bad06b84e3435ba872f331d0fa73
https://doi.org/10.1523/jneurosci.1246-16.2016
https://doi.org/10.1523/jneurosci.1246-16.2016
Publikováno v:
Behavioural Brain Research. 284:238-248
The Rest/Nrsf transcriptional repressor modulates expression of a large set of neural specific genes. Many of these target genes have well characterized roles in nervous system processes including development, plasticity and synaptogenesis. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61df4b7f6296c5b65f04d08263f79e3
https://doi.org/10.1016/j.bbr.2015.02.026
https://doi.org/10.1016/j.bbr.2015.02.026