Zobrazeno 1 - 10
of 3 928
pro vyhledávání: '"Cara E"'
Autor:
Cara E. Toscan, Hannah McCalmont, Amir Ashoorzadeh, Xiaojing Lin, Zhe Fu, Louise Doculara, Hansen J. Kosasih, Roxanne Cadiz, Anthony Zhou, Sarah Williams, Kathryn Evans, Faezeh Khalili, Ruilin Cai, Kristy L. Yeats, Andrew J. Gifford, Russell Pickford, Chelsea Mayoh, Jinhan Xie, Michelle J. Henderson, Toby N. Trahair, Adam V. Patterson, Jeff B. Smaill, Charles E. de Bock, Richard B. Lock
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that expresses high levels of the enzyme aldo-keto reductase family 1 member C3 (AKR1C3). To exploit this finding, we developed a novel prodrug, ACHM-025,
Externí odkaz:
https://doaj.org/article/6345a011fd5e4b7dbeced8196c76971a
Autor:
Peter Truong, Sylvie Shen, Swapna Joshi, Md Imtiazul Islam, Ling Zhong, Mark J. Raftery, Ali Afrasiabi, Hamid Alinejad-Rokny, Mary Nguyen, Xiaoheng Zou, Golam Sarower Bhuyan, Chowdhury H. Sarowar, Elaheh S. Ghodousi, Olivia Stonehouse, Sara Mohamed, Cara E. Toscan, Patrick Connerty, Purvi M. Kakadia, Stefan K. Bohlander, Katharine A. Michie, Jonas Larsson, Richard B. Lock, Carl R. Walkley, Julie A. I. Thoms, Christopher J. Jolly, John E. Pimanda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Hypomethylating agents (HMAs) are frontline therapies for Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are commonplace. To address this, we perform a genome-wide CRISPR-
Externí odkaz:
https://doaj.org/article/73815292edce4c1d9476e3fd55ac41f7
Autor:
Sophia Horigan, Gwenddolen Kettenburg, Amy Kistler, Hafaliana C. Ranaivoson, Angelo Andrianiaina, Santino Andry, Vololoniaina Raharinosy, Tsiry Hasina Randriambolamanantsoa, Cristina M. Tato, Vincent Lacoste, Jean-Michel Heraud, Philippe Dussart, Cara E. Brook
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Bats (order: Chiroptera) are known to host a diverse range of viruses, some of which present a human public health risk. Thorough viral surveillance is therefore essential to predict and potentially mitigate zoonotic spillover. Astroviruses
Externí odkaz:
https://doaj.org/article/ec2f2699897c45b0b243bd8256d0588f
Autor:
Bing Zhang, Kevin M. Magnaye, Emily Stryker, Jacqueline Moltzau-Anderson, Cara E. Porsche, Sandra Hertz, Kathryn E. McCauley, Byron J. Smith, Martin Zydek, Katherine S. Pollard, Averil Ma, Najwa El-Nachef, Susan V. Lynch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Fecal microbial transplantation (FMT) offers promise for treating ulcerative colitis (UC), though the mechanisms underlying treatment failure are unknown. This study harnessed longitudinally collected colonic biopsies (n = 38) and fecal samp
Externí odkaz:
https://doaj.org/article/576b08f394f04518b69fee360918961e
Autor:
Julia L. Xia, Monica K. Ertel, Amit K. Reddy, Alan G. Palestine, Arthur J. Stanley, Cara E. Capitena Young, Mina B. Pantcheva
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 9, Pp 2495-2503 (2024)
Abstract Purpose To report a case series of patients with uveitic glaucoma who were treated with micropulse transscleral cyclophotocoagulation (mpCPC). Methods This retrospective case series consists of patients from the University of Colorado Sue An
Externí odkaz:
https://doaj.org/article/aa8f8866c20a435f9510e4328c54aaf4
Autor:
Germaine J. M. Yong, Cara E. Porsche, Alexandra R. Sitarik, Kei E. Fujimura, Kathryn McCauley, Dat T. Nguyen, Albert M. Levin, Kimberley J. Woodcroft, Dennis R. Ownby, Andrew G. Rundle, Christine C. Johnson, Andrea Cassidy-Bushrow, Susan V. Lynch
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTEarly life gut microbiome composition has been correlated with childhood obesity, though microbial functional contributions to disease origins remain unclear. Here, using an infant birth cohort (n = 349) we identify a distinct fecal microbiot
Externí odkaz:
https://doaj.org/article/03d3632a2e5a42ce9c7a4123c0dc23ae
Autor:
René Marcella Kronlage, Amy S Stanley, Miranda J Reid, William Hudson Shaw, Cara E House, Michele N Lossius, Artenisa Kulla, Kendyll Coxen, Phillip M Mackie, Carolyn K Holland
Publikováno v:
BMJ Open Quality, Vol 13, Iss 4 (2024)
Background The University of Florida (UF) Equal Access Clinic Network (EACN) is the largest student-run free healthcare clinic network in Florida. The UF EACN serves those who are underinsured or uninsured in Alachua County and its surrounding area.
Externí odkaz:
https://doaj.org/article/75fd4aba41d84f0592776b030bcf2415
Autor:
Jean-Michel Heraud, Cara E Brook, Norosoa Harline Razanajatovo, Vincent Lacoste, Tsiry Hasina Randriambolamanantsoa, Hafaliana Christian Ranaivoson, Laurence Randrianasolo, Hasina Joelinotahiana Rabarison, Helisoa Razafimanjato, Arvé Ratsimbazafy, Danielle Aurore Doll Rakoto
Publikováno v:
BMJ Public Health, Vol 2, Iss 2 (2024)
Introduction Respiratory syncytial virus (RSV) is a primary source of acute lower respiratory tract infection, the leading cause of death in children under 5. Over 99% of RSV-attributed deaths occur in low-income countries, including Madagascar. RSV
Externí odkaz:
https://doaj.org/article/edd3c76c655c4544baff8df8ea7632b3
Autor:
Sophia Horigan, Gwenddolen Kettenburg, Amy Kistler, Hafaliana C. Ranaivoson, Angelo Andrianiaina, Santino Andry, Vololoniaina Raharinosy, Tsiry Hasina Randriambolamanantsoa, Cristina M. Tato, Vincent Lacoste, Jean-Michel Heraud, Philippe Dussart, Cara E. Brook
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/4189e67ca9174276a37667822199fffc
Autor:
Lindsey R Perry, Rebecca L Kelble, Valerie N Brewer, Cara E Christensen, Mark E Kerstens, Terrah M Owens, Megan A Sampognaro, Dorothy L Zahor, Rachel A Zitomer, Suzanne H Austin, Jamie M Cornelius, Jonathan B Dinkins, Sarah J K Frey, Cecelia E Frisinger, Stephanie M LeQuier, Carl G Lundblad, Jamie Oskowski, Hallie R Perlman, William J Price, Richard Rich, Kayla A Ruth, Vanessa M Schroeder, Shawn B Szabo, James W Rivers
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012189 (2024)
Externí odkaz:
https://doaj.org/article/f851621cb45e41b99ad56885febbb55e