Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cara Cesario"'
Publikováno v:
Organic Letters. 11:4076-4079
Homoallylic esters are obtained in a single transformation from allyl 2,2,2-trifluoroethyl malonates by using a Pd(0) catalyst. Facile decarboxylation of allyl 2,2,2-trifluoroethyl malonates is attributed to a decrease in pK(a) compared to allyl meth
Autor:
Marvin J. Miller, Cara Cesario
Publikováno v:
The Journal of Organic Chemistry. 74:5730-5733
Carbocyclic uracil polyoxin C analogs are prepared from an acylnitroso-derived hetero Diels−Alder cycloadduct in fewer than nine steps. Pd(0)/InI-mediated allylation of 4-acetoxy-2-azetidinone is used to install the β-amino acid side chain at the
Titanocene(III) Chloride-Mediated Reductions of Oxazines, Hydroxamic Acids, and N-Hydroxy Carbamates
Publikováno v:
The Journal of Organic Chemistry. 74:448-451
Titanocene(III) chloride (Cp(2)TiCl), generated in situ, reduces N-O bonds of various substrates in good to excellent yields (72-95%). Reactions may be performed with stoichiometric Cp(2)TiCl or with catalytic Cp(2)TiCl.
Autor:
Neil W. Gibson, Patricia Beck, Andrew Cooke, Feng-Lei Sun, Vanessa Smith, Michael Vrkljan, Mark Bittner, Mark J. Mulvihill, Anthony Nigro, David M. Keane, Arlindo L. Castelhano, Cara Cesario, Julie L.C. Kan, David L. Emerson, Shannon L. Winski, Mary Srebernak, Christy Nillson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1669-1673
A series of [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines were designed and synthesized as CYP26 inhibitors, serving as retinoic acid metabolic blocking agents (RAMBA's).
Publikováno v:
The Journal of Organic Chemistry. 69:5124-5127
The regio- and stereospecific conversion of syn- and anti-1,2-amino alcohols to their respective syn- and anti-1,2-imidazolylpropylamines via treatment with 1,1'-carbonyldiimidazole is described. The rationale behind the regio- and stereospecific nat
Autor:
Cara Cesario, Marvin J. Miller
Publikováno v:
Tetrahedron Letters. 51:3050-3052
A formyl equivalent was generated in situ from Eschenmoser’s salt in aqueous THF and was reacted with an allylindium species. Acylnitroso-derived hetero-Diels Alder adducts and related allyl acetates were shown to be substrates for Pd(0)/InI-mediat
Publikováno v:
Tetrahedron letters. 51(23)
Carbocyclic aminonucleosides and epi-4′-carbocyclic puromycin were prepared from an acylnitroso-derived hetero Diels–Alder cycloadduct. Pd(0)/InI-mediated allylations of a formyl species were used to install the 4′-hydroxymethyl group. A tether
Publikováno v:
ChemInform. 40
Titanocene(III) chloride (Cp(2)TiCl), generated in situ, reduces N-O bonds of various substrates in good to excellent yields (72-95%). Reactions may be performed with stoichiometric Cp(2)TiCl or with catalytic Cp(2)TiCl.
Autor:
Cara Cesario, Marvin J. Miller
Publikováno v:
Organic letters. 11(6)
Acylnitroso-derived hetero-Diels-Alder cycloadducts are susceptible to C-O bond cleavage with Pd(0) and InI to form allylic indium(III) species. The in situ prepared allylindium compounds readily react at room temperature with Eschenmoser's salt. All