Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Cara C. Wilson"'
Autor:
Nicholas Dopkins, Tongyi Fei, Stephanie Michael, Nicholas Liotta, Kejun Guo, Kaylee L. Mickens, Brad S. Barrett, Matthew L. Bendall, Stephanie M. Dillon, Cara C. Wilson, Mario L. Santiago, Douglas F. Nixon
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105133- (2024)
Summary: Background: Endogenous retroelements (EREs), including human endogenous retroviruses (HERVs) and long interspersed nuclear elements (LINEs), comprise almost half of the human genome. Our previous studies of the interferome in the gut suggest
Externí odkaz:
https://doaj.org/article/77bd4000351b463188eba2fb539d30cc
Autor:
Stephanie M. Dillon, Kaylee L. Mickens, Tezha A. Thompson, Emily H. Cooper, Sabrina Nesladek, Allison J. Christians, Moriah Castleman, Kejun Guo, Cheyret Wood, Daniel N. Frank, Katerina Kechris, Mario L. Santiago, Cara C. Wilson
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Chronic HIV-1 infection results in the sustained disruption of gut homeostasis culminating in alterations in microbial communities (dysbiosis) and increased microbial translocation. Major questions remain on how interactions between translocating mic
Externí odkaz:
https://doaj.org/article/54b024d5ab0a42a08f2c056a33def948
Autor:
Stephanie M. Dillon, Tezha A. Thompson, Allison J. Christians, Martin D. McCarter, Cara C. Wilson
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-10 (2021)
Abstract Background The etiology of the low-level chronic inflammatory state associated with aging is likely multifactorial, but a number of animal and human studies have implicated a functional decline of the gastrointestinal immune system as a pote
Externí odkaz:
https://doaj.org/article/0d6f3d8b06844524b45b31c5a6c1406e
Autor:
Dana Gabuzda, Beth D. Jamieson, Ronald G. Collman, Michael M. Lederman, Tricia H. Burdo, Steven G. Deeks, Dirk P. Dittmer, Howard S. Fox, Nicholas T. Funderburg, Savita G. Pahwa, Ivona Pandrea, Cara C. Wilson, Peter W. Hunt
Publikováno v:
Pathogens and Immunity, Vol 5, Iss 1, Pp 143-174 (2020)
People with HIV (PWH) experience accentuated biological aging, as defined by markers of inflammation, immune dysfunction, and the epigenetic clock. They also have an elevated risk of multiple age-associated comorbidities. To discuss current knowle
Externí odkaz:
https://doaj.org/article/67523edc367641d89c52c3931673c54e
Autor:
Kristine M. Erlandson, Jay Liu, Rachel Johnson, Stephanie Dillon, Catherine M. Jankowski, Miranda Kroehl, Charles E. Robertson, Daniel N. Frank, Yunus Tuncil, Janine Higgins, Bruce Hamaker, Cara C. Wilson
Publikováno v:
Therapeutic Advances in Infectious Disease, Vol 8 (2021)
Background: Physiologic aging has been associated with gut dysbiosis. Although short exercise interventions have been linked to beneficial changes in gut microbiota in younger adults, limited data are available from older populations. We hypothesized
Externí odkaz:
https://doaj.org/article/889dbdd0e7db4a6dacfe8d27632a628f
Autor:
Brett B. Williams, Stefan J. Green, Ronald J. Bosch, Ellen S. Chan, Jeffrey M. Jacobson, David M. Margolis, Phillip Engen, Alan L. Landay, Cara C. Wilson
Publikováno v:
Pathogens and Immunity, Vol 4, Iss 2, Pp 235-250 (2019)
Introduction: HIV-infected individuals have evidence of intestinal microbial translocation which is associated with immune activation and unfavorable clinical outcomes. Rifaximin, a non-absorbable antibiotic which reduces microbial translocation in o
Externí odkaz:
https://doaj.org/article/40071feb20974bfeaeafc529de3a8c9c
Autor:
Jay Liu, Rachel Johnson, Stephanie Dillon, Miranda Kroehl, Daniel N. Frank, Yunus E. Tuncil, Xiaowei Zhang, Diana Ir, Charles E. Robertson, Sharon Seifert, Janine Higgins, Bruce Hamaker, Cara C. Wilson, Kristine M. Erlandson
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 583-594 (2019)
Background: HIV-1 infection and physiological aging are independently linked to elevated systemic inflammation and changes in enteric microbial communities (dysbiosis). However, knowledge of the direct effect of HIV infection on the aging microbiome
Externí odkaz:
https://doaj.org/article/9d0576080e0645b29341c81aa582fa90
Autor:
Moriah J. Castleman, Stephanie M. Dillon, Christine M. Purba, Andrew C. Cogswell, Jon J. Kibbie, Martin D. McCarter, Mario L. Santiago, Edward Barker, Cara C. Wilson
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Innate lymphoid cells (ILCs) are a diverse family of cells that play critical roles in mucosal immunity. One subset of the ILC family, Group 3 ILCs (ILC3s), has been shown to aid in gut homeostasis through the production of IL-22. IL-22 promotes gut
Externí odkaz:
https://doaj.org/article/d9aa38cd56ae45b986070ebf9b729160
Autor:
Sean T. Jones, Kejun Guo, Emily H. Cooper, Stephanie M. Dillon, Cheyret Wood, David H. Nguyen, Guannan Shen, Bradley S. Barrett, Daniel N. Frank, Miranda Kroehl, Edward N. Janoff, Katerina Kechris, Cara C. Wilson, Mario L. Santiago
Publikováno v:
Journal of virology. 96(17)
Humoral immune perturbations contribute to pathogenic outcomes in persons with HIV-1 infection (PWH). Gut barrier dysfunction in PWH is associated with microbial translocation and alterations in microbial communities (dysbiosis), and IgA, the most ab
Autor:
Cara C. Wilson, Stephanie M. Dillon
Publikováno v:
Current HIV/AIDS Reports. 18:128-138
In the gastro-intestinal tract, the complex network of multiple innate cell populations play critical roles not only as a first line of defense against invading pathogens and in driving adaptive immune responses but also in maintaining intestinal hom