Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cara C. Hardy"'
Autor:
Cara C. Hardy
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Bothersome urinary symptoms plague many older adults and disproportionally affect women. Underreporting of symptoms and general stigma/embarrassment associated with incontinence has negatively impacted the availability of treatments, as research cann
Externí odkaz:
https://doaj.org/article/529c8e0e0e7341858f20630343945f51
Autor:
Ramalakshmi Ramasamy, Dylan S. Baker, Fouad Lemtiri-Chlieh, Dawn A. Rosenberg, Eric Woon, Iman M. Al-Naggar, Cara C. Hardy, Eric S. Levine, George A. Kuchel, Jenna M. Bartley, Phillip P. Smith
Publikováno v:
Biogerontology
Volume hyposensitivity resulting from impaired sympathetic detrusor relaxation during bladder filling contributes to detrusor underactivity (DU) associated with aging. Detrusor tension regulation provides an adaptive sensory input of bladder volume t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac043c576b5d118f36a8b591da359b0
https://doi.org/10.1007/s10522-022-10005-y
https://doi.org/10.1007/s10522-022-10005-y
Autor:
Cara C. Hardy, Ramalakshmi Ramasamy, Dawn A. Rosenberg, George A. Kuchel, Riqiang Yan, Xiangyou Hu, Phillip P. Smith
Publikováno v:
Neurourology and urodynamicsREFERENCES. 41(6)
While most Alzheimer's disease (AD) research emphasizes cognitive and behavioral abnormalities, lower urinary tract symptoms (LUTS) are observed in a third of AD patients, contributing to morbidity, poor quality of life, and need for institutionaliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4e953a8780d253701882b23cc95eaf
https://pubmed.ncbi.nlm.nih.gov/35579273
https://pubmed.ncbi.nlm.nih.gov/35579273
Autor:
Cara C Hardy, Phillip P. Smith, Diane Luo, Anahita Amiri, Santhosh Sivajothi, Iman M. Al-Naggar, Dylan Baker, William F. Flynn, Paul Robson, George A. Kuchel
SUMMARYThe urinary bladder functions as a reservoir to store and extrude liquid bodily waste. Significant debate exists as to this tissue’s cellular composition and genes associated with their functions. We use a repertoire of cell profiling tools
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89deb33742c2ce68ceef9f7e6c6ee7f0
https://doi.org/10.1101/2021.09.20.461121
https://doi.org/10.1101/2021.09.20.461121
Autor:
Constantine M. Poulos, Iman M. Al-Naggar, Benjamin T. Ristau, Akila B. Ramaraj, Eric D. Girard, Gail M. Sullivan, Azuka Onye Otukoya, Christina Stevenson, Jeffrey B. Gross, Adam Sachs, Ryan Millea, Irfan Ali, Eric M. Mortensen, Zulara N. Wahla, Brian D. Shames, Lindsay A. Bliss, Nicole Silverstein, Cara C Hardy, Patrick P. Coll, Joy Liang, Phillip P. Smith, James Nolan, David W. McFadden, Marilyn Katz
Publikováno v:
Current Problems in Surgery. 56:260-329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a5077e555c684c0439bc64569af1c2
https://doi.org/10.1067/j.cpsurg.2019.03.003
https://doi.org/10.1067/j.cpsurg.2019.03.003
Publikováno v:
J Gerontol A Biol Sci Med Sci
A geroscience-informed approach to the increasing prevalence of bladder control problems in older adults requires understanding the impact of aging on dynamic mechanisms that ensure resilience in response to stressors challenging asymptomatic volunta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbbf8de47db8317cab6878344b5c12f
https://pubmed.ncbi.nlm.nih.gov/33693872
https://pubmed.ncbi.nlm.nih.gov/33693872
Autor:
Cara C Hardy, Omar G Taweh, Phillip P. Smith, Iman M. Al-Naggar, George A. Kuchel, Daniel K. Mulkey, Titas Grabauskas
Publikováno v:
The Journals of Gerontology: Series A. 74:325-329
The Hyperpolarization activated, cyclic nucleotide gated (HCN) channel is a candidate mediator of neuroendocrine influence over detrusor tonus during filling. In other tissues, HCN loss with aging is linked to declines in rhythmicity and function. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc9f524fd140594eaf96dcb69275871
https://doi.org/10.1093/gerona/gly137
https://doi.org/10.1093/gerona/gly137
Autor:
Phillip P. Smith, Dylan Baker, Cara C Hardy, Andrew G. Harrison, B. Knight, Spencer R. Keilich
Publikováno v:
Neurourology and urodynamics. 38(8)
Aims The prevalence of urinary dysfunction increases with age, yet therapies are often suboptimal. Incomplete understanding of the linkages between system, organ, and tissue domains across lifespan remains a knowledge gap. If tissue-level changes dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a556eb8b7d32a1826c32a35a864a07
https://pubmed.ncbi.nlm.nih.gov/31452236
https://pubmed.ncbi.nlm.nih.gov/31452236
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6ca270cea056d9ad236dc63f21f8f3e
https://doi.org/10.1096/fasebj.28.1_supplement.606.6
https://doi.org/10.1096/fasebj.28.1_supplement.606.6
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e605056e14b18872dda3f7e60fd78509
https://doi.org/10.1096/fasebj.27.1_supplement.814.4
https://doi.org/10.1096/fasebj.27.1_supplement.814.4