Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Carén Helena"'
Publikováno v:
Molecular Cancer, Vol 11, Iss 1, p 40 (2012)
Abstract Background Hypermethylation of promotor CpG islands is a common mechanism that inactivates tumor suppressor genes in cancer. Genes belonging to the RASSF gene family have frequently been reported as epigenetically silenced by promotor methyl
Externí odkaz:
https://doaj.org/article/15dfb6cdb5724202bccece1c44412c70
Autor:
Kogner Per, Abrahamsson Jonas, Sjöberg Rose-Marie, Erichsen Jennie, Carén Helena, Kryh Hanna, Martinsson Tommy
Publikováno v:
BMC Genomics, Vol 12, Iss 1, p 443 (2011)
Abstract Background Copy neutral loss of heterozygosity (CN-LOH) refers to a special case of LOH occurring without any resulting loss in copy number. These alterations is sometimes seen in tumors as a way to inactivate a tumor suppressor gene and hav
Externí odkaz:
https://doaj.org/article/5e37812c6e954665a11cd0a4565e3bb6
Autor:
Lagerstedt Kristina, Lönnroth Christina, Andersson Marianne, Carén Helena, Asting Annika, Lundholm Kent
Publikováno v:
BMC Cancer, Vol 11, Iss 1, p 238 (2011)
Abstract Background Increased cyclooxygenase activity promotes progression of colorectal cancer, but the mechanisms behind COX-2 induction remain elusive. This study was therefore aimed to define external cell signaling and transcription factors rela
Externí odkaz:
https://doaj.org/article/0f62d57c6dbe4de880534a62c592326a
Autor:
Enström Camilla, Kogner Per, Sjöberg Rose-Marie, Nethander Maria, Djos Anna, Carén Helena, Nilsson Staffan, Martinsson Tommy
Publikováno v:
BMC Cancer, Vol 11, Iss 1, p 66 (2011)
Abstract Background Epigenetic mechanisms such as DNA methylation and histone modifications are important regulators of gene expression and are frequently involved in silencing tumor suppressor genes. Methods In order to identify genes that are epige
Externí odkaz:
https://doaj.org/article/24271b3b8fb8484c8b4906c0bc7f770b
Autor:
Kogner Per, Nilsson Staffan, Carén Helena, Bergman Annika, Thorell Kaisa, Martinsson Tommy, Abel Frida
Publikováno v:
BMC Medical Genomics, Vol 2, Iss 1, p 53 (2009)
Abstract Background One of the most striking features of the childhood malignancy neuroblastoma (NB) is its clinical heterogeneity. Although there is a great need for better clinical and biological markers to distinguish between tumours with differen
Externí odkaz:
https://doaj.org/article/4c0a485d3867457483f992a844395961
Autor:
Kogner Per, Abrahamsson Jonas, Sjöberg Rose-Marie, Enerbäck Charlotta, Olsson Linda, Erichsen Jennie, Carén Helena, Martinsson Tommy
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 353 (2008)
Abstract Background Neuroblastoma is a very heterogeneous pediatric tumor of the sympathetic nervous system showing clinically significant patterns of genetic alterations. Favorable tumors usually have near-triploid karyotypes with few structural rea
Externí odkaz:
https://doaj.org/article/6cd8a17cbc0c4039b7fb36d12e7d274e
Autor:
Li Lingli, Zaibak Faten, Carén Helena, Krona Cecilia, Ejeskär Katarina, Martinsson Tommy, Ioannou Panayiotis A
Publikováno v:
BMC Cancer, Vol 5, Iss 1, p 161 (2005)
Abstract Background Neuroblastoma is a solid tumour of childhood often with an unfavourable outcome. One common genetic feature in aggressive tumours is 1p-deletion. The α-enolase (ENO1) gene is located in chromosome region 1p36.2, within the common
Externí odkaz:
https://doaj.org/article/b783dec7f4134183b590eb7da6f0565e
Autor:
Krona Cecilia, Sjöberg Rose-Marie, Latif Farida, Hesson Luke, Fransson Susanne, Ejeskär Katarina, Carén Helena, Martinsson Tommy
Publikováno v:
Molecular Cancer, Vol 4, Iss 1, p 10 (2005)
Abstract Background A common feature of neuroblastoma tumours are partial deletions of the short arm of chromosome 1 (1p-deletions). This is indicative of a neuroblastoma tumour suppressor gene being located in the region. Several groups including ou
Externí odkaz:
https://doaj.org/article/328aaefc2ffc4f18839f5991dc366f0c
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