Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Cappellazzo Coelho A"'
Functional characterization of Cullin-1-RING ubiquitin ligase (CRL1) complex in Leishmania infantum.
Autor:
Camila Rolemberg Santana Travaglini Berti de Correia, Caroline Torres, Ellen Gomes, Giovana Maffei Rodriguez, Wesley Klaysson Pereira Regatieri, Nayore Tamie Takamiya, Luana Aparecida Rogerio, Iran Malavazi, Marcelo Damário Gomes, Jeziel Dener Damasceno, Vitor Luiz da Silva, Marcos Antonio Fernandes de Oliveira, Marcelo Santos da Silva, Alessandro Silva Nascimento, Adriano Cappellazzo Coelho, Sandra Regina Maruyama, Felipe Roberti Teixeira
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012336 (2024)
Cullin-1-RING ubiquitin ligases (CRL1) or SCF1 (SKP1-CUL1-RBX1) E3 ubiquitin ligases are the largest and most extensively investigated class of E3 ligases in mammals that regulate fundamental processes, such as the cell cycle and proliferation. These
Externí odkaz:
https://doaj.org/article/bd422a1d7391403bbcd305989862dc2b
Autor:
Yuan Zeng, Yuqin Song, Lanqing Cui, Qi Wu, Chao Wang, Adriano Cappellazzo Coelho, Gang Zhang, Dawei Wei, Chao Li, Jingren Zhang, Jacques Corbeil, Yun Li, Jie Feng
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Streptococcus pneumoniae is a gram-positive opportunistic pathogen, and infection risks of S. pneumoniae can be profoundly augmented by its acquired multidrug-resistance (MDR). The rapid development of MDR in S. pneumoniae was att
Externí odkaz:
https://doaj.org/article/d17da07d9ab7441fa3cc0f4cf94b56d5
Akademický článek
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Publikováno v:
Microorganisms, Vol 8, Iss 11, p 1632 (2020)
Leishmaniasis is a neglected tropical disease with two main clinical forms: cutaneous and visceral leishmaniasis. Diagnosis of leishmaniasis is still a challenge, concerning the detection and correct identification of the species of the parasite, mai
Externí odkaz:
https://doaj.org/article/e48f0cb30cca4b8594a1f36173d41137
Autor:
Juliana Ide Aoki, Adriano Cappellazzo Coelho, Sandra Marcia Muxel, Ricardo Andrade Zampieri, Eduardo Milton Ramos Sanchez, Audun Helge Nerland, Lucile Maria Floeter-Winter, Paulo Cesar Cotrim
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004972 (2016)
BACKGROUND:Tubercidin (TUB) is a toxic adenosine analog with potential antiparasitic activity against Leishmania, with mechanism of action and resistance that are not completely understood. For understanding the mechanisms of action and identifying t
Externí odkaz:
https://doaj.org/article/22d50a4e755e42308af3ecd1ce199c9f
Autor:
Fernanda Ramos Gadelha, Mariana Borges Costa Brioschi, Adriano Cappellazzo Coelho, Elizabeth Magiolo Coser, Danilo Ciccone Miguel
Publikováno v:
International journal of antimicrobial agents. 60(2)
A growing number of studies have demonstrated the in vitro potential of an impressive number of antileishmanial candidates in the past years. However, the lack of uniformity regarding the choice of cell types for cytotoxicity assays may lead to uncom
Investigation of the role of ABC proteins in the resistance to paromomycin in Leishmania amazonensis
Publikováno v:
Revista dos Trabalhos de Iniciação Científica da UNICAMP.
Leishmaniasis is a parasitic disease with wide geographic distribution in tropical and subtropical areas, including Brazil where an increased number of cases in urban areas has been reported in the recent years. No vaccines are available for control
Autor:
Carina Scolari, Gosch, Bruna Silva, Resende, Célia Bastos, Amorim, Cálita Pollyanna, Marques, Ledice Inacia de Araújo, Pereira, Sebastião Alves, Pinto, Silvia Reni Bortolin, Uliana, Adriano Cappellazzo, Coelho, Fátima, Ribeiro-Dias, Miriam Leandro, Dorta
Publikováno v:
The American journal of tropical medicine and hygiene. 99(5)
The disseminated form of leishmaniasis is a serious and rare disease, being diagnosed in 2% of the cutaneous cases registered per year in Brazil. The main characteristic is the appearance of multiple pleomorphic lesions on the cutaneous surface. A 68
Autor:
Scolari Gosch, Carina, Silva Resende, Bruna, Bastos Amorim, Célia, Pollyanna Marques, Cálita, de Araú jo Pereira, Ledice Inacia, Alves Pinto, Sebastião, Bortolin Uliana, Silvia Reni, Cappellazzo Coelho, Adriano, Ribeiro-Dias, Fátima, Leandro Dorta, Miriam
Publikováno v:
American Journal of Tropical Medicine & Hygiene; 2018, Vol. 99 Issue 5, p1165-1169, 5p
Autor:
Adriano Cappellazzo Coelho
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Pouco se sabe sobre o mecanismo de ação da pentamidina, um composto utilizado no tratamento das leishmanioses. Para uma melhor compreensão do mecanismo de ação assim como o mecanismo de resistência à pentamidina, foi isolado um gene que codifi