Zobrazeno 1 - 10 of 38 pro vyhledávání: '"Capeleto B"'
1
Akademický článek
Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies.
Autor: Bezençon O; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Heidmann B; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Siegrist R; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Stamm S; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Richard S; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Pozzi D; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Corminboeuf O; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Roch C; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Kessler M; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Ertel EA; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Reymond I; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Pfeifer T; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., de Kanter R; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Toeroek-Schafroth M; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Moccia LG; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Mawet J; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Moon R; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Rey M; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Capeleto B; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Fournier E; Chemistry, Biology and Pharmacology & Pre-clinical Development, Drug Discovery, Idorsia Pharmaceuticals Ltd. , Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2017 Dec 14; Vol. 60 (23), pp. 9769-9789. Date of Electronic Publication: 2017 Nov 20.
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2
Akademický článek
Discovery and evaluation of Ca v 3.2-selective T-type calcium channel blockers.
Autor: Bezençon O; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland. Electronic address: olivier.bezencon@idorsia.com., Remeň L; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Richard S; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Roch C; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Kessler M; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Ertel EA; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Moon R; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Mawet J; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Pfeifer T; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland., Capeleto B; Drug Discovery Chemistry, Biology and Pharmacology, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Dec 01; Vol. 27 (23), pp. 5326-5331. Date of Electronic Publication: 2017 Sep 30.
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3
Akademický článek
Milestones to the Discovery of T-type Calcium Channel Blockers for the Treatment of Generalized Epilepsies.
Autor: Bezençon O; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil;, Email: olivier.bezencon@idorsia.com., Siegrist R; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Heidmann B; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Pozzi D; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Stamm S; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Remeň L; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Richard S; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Simons L; Kalexsyn, Inc. 4502 Campus Drive, Kalamazoo, MI 49008, USA., Gaston R; Kalexsyn, Inc. 4502 Campus Drive, Kalamazoo, MI 49008, USA., Downing D; Kalexsyn, Inc. 4502 Campus Drive, Kalamazoo, MI 49008, USA., Grisostomi C; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Roch C; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Kessler M; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Gatfield J; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Moon R; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Pfeifer T; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Mosbacher J; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Reymond I; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Ertel EA; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., de Kanter R; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Capeleto B; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Fournier E; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Rey M; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Moccia L; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Toeroek-Schafroth M; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Roscher R; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil., Schindelholz B; Idorsia Pharmaceuticals Ltd Hegenheimermattweg 91, CH-4123 Allschwil.
Publikováno v: Chimia [Chimia (Aarau)] 2017 Oct 25; Vol. 71 (10), pp. 722-729.
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4
Akademický článek
Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist.
Autor: Iglarz M; Drug Discovery Department, Actelion Pharmaceuticals Ltd., Allschwil, Switzerland., Binkert C, Morrison K, Fischli W, Gatfield J, Treiber A, Weller T, Bolli MH, Boss C, Buchmann S, Capeleto B, Hess P, Qiu C, Clozel M
Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2008 Dec; Vol. 327 (3), pp. 736-45. Date of Electronic Publication: 2008 Sep 09.
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5
Akademický článek
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6
Akademický článek
Exploring the failing right ventricle in pulmonary hypertension by cardiac magnetic resonance: An in vivo study utilizing Macitentan.
Autor: Murphy, Gerard1 (AUTHOR), Jayasekera, Geeshath1 (AUTHOR), Mullin, James2 (AUTHOR), Gallagher, Lindsay2 (AUTHOR), Welsh, David J.1 (AUTHOR) david.welsh@gcu.ac.uk
Publikováno v: Pulmonary Circulation. Jul2022, Vol. 12 Issue 3, p1-14. 14p.
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8
Akademický článek
Taming resistant hypertension: The promise of novel pharmacologic approaches and renal denervation.
Autor: Azzam O; Dobney Hypertension Centre, Medical School-Royal Perth Hospital Unit, Royal Perth Hospital Medical Research Foundation, The University of Western Australia, Perth, Western Australia, Australia.; Department of Nephrology, Royal Perth Hospital, Perth, Western Australia, Australia., Nejad SH; Dobney Hypertension Centre, Medical School-Royal Perth Hospital Unit, Royal Perth Hospital Medical Research Foundation, The University of Western Australia, Perth, Western Australia, Australia., Carnagarin R; Dobney Hypertension Centre, Medical School-Royal Perth Hospital Unit, Royal Perth Hospital Medical Research Foundation, The University of Western Australia, Perth, Western Australia, Australia., Nolde JM; Dobney Hypertension Centre, Medical School-Royal Perth Hospital Unit, Royal Perth Hospital Medical Research Foundation, The University of Western Australia, Perth, Western Australia, Australia., Galindo-Kiuchi M; Dobney Hypertension Centre, Medical School-Royal Perth Hospital Unit, Royal Perth Hospital Medical Research Foundation, The University of Western Australia, Perth, Western Australia, Australia., Schlaich MP; Dobney Hypertension Centre, Medical School-Royal Perth Hospital Unit, Royal Perth Hospital Medical Research Foundation, The University of Western Australia, Perth, Western Australia, Australia.; Department of Nephrology, Royal Perth Hospital, Perth, Western Australia, Australia.; Department of Cardiology, Royal Perth Hospital, Perth, Western Australia, Australia.
Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Feb; Vol. 181 (3), pp. 319-339. Date of Electronic Publication: 2023 Oct 21.
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