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Glucose-dependent glycosphingolipid biosynthesis fuels CD8 ⁺ T cell function and tumor control.

Autor: Longo J; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA., DeCamp LM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA., Oswald BM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA., Teis R; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA., Reyes-Oliveras A; Department of Cell Biology, Van Andel Institute, Grand Rapids, MI, USA., Dahabieh MS; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA., Ellis AE; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA., Vincent MP; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA., Damico H; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI, USA., Gallik KL; Optical Imaging Core, Van Andel Institute, Grand Rapids, MI, USA., Compton SE; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA., Capan CD; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA., Williams KS; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.; Metabolism and Nutrition Program, Van Andel Institute, Grand Rapids, MI, USA., Esquibel CR; Optical Imaging Core, Van Andel Institute, Grand Rapids, MI, USA., Madaj ZB; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI, USA., Lee H; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA., Roy DG; Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Canada.; Institut du Cancer de Montréal, Montréal, Canada., Krawczyk CM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA., Haab BB; Department of Cell Biology, Van Andel Institute, Grand Rapids, MI, USA., Sheldon RD; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA., Jones RG; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.; Metabolism and Nutrition Program, Van Andel Institute, Grand Rapids, MI, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.