Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Capacci Andrew George"'
Autor:
Michael Dechantsreiter, Brian Lucas, John Howard Jones, Istvan J. Enyedy, Bing Li, Capacci Andrew George, Douglas Marcotte, Bin Ma, Guangqing Xiao, Karl E.G. Richter, Edward Yin-Shiang Lin
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(4)
Nrf2 is a transcription factor regulating expression of the Phase II Antioxidant Response and plays an important role in neuroprotection and detoxification. Nrf2 activation is inhibited by interaction with Keap1. Covalent Keap1 inhibitors such as dim
Autor:
Erik C. Hett, Michelle L. Ols, Kejie Li, Elisabeth Vollman, Tricia L. May-Dracka, Tracy J. Jenkins, Paramasivam Murugan, Weike Zeng, Jun Feng, Kate L. Henry, Capacci Andrew George, Andrea Bertolotti-Ciarlet, Ellen Cahir-McFarland, Brian Lucas, Christine Loh, Alan Buckler, Thomas Cameron, Peter Juhasz, Brian T. Hopkins, Katelin A. Ennis, John E. Anderson, Mercedes Beyna, Benbo Gao, Debra Kellner, Norm Allaire, Govinda Bhisetti, Ru Wei, Bekim Bajrami
Publikováno v:
Science signaling. 11(541)
Members of the family of nuclear factor κB (NF-κB) transcription factors are critical for multiple cellular processes, including regulating innate and adaptive immune responses, cell proliferation, and cell survival. Canonical NF-κB complexes are