Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Canzhao Liu"'
Autor:
Runkai Chen, Hongrui Zhang, Botao Tang, Yukun Luo, Yufei Yang, Xin Zhong, Sifei Chen, Xinjie Xu, Shengkang Huang, Canzhao Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-44 (2024)
Abstract The immune response holds a pivotal role in cardiovascular disease development. As multifunctional cells of the innate immune system, macrophages play an essential role in initial inflammatory response that occurs following cardiovascular in
Externí odkaz:
https://doaj.org/article/4cd2c269d2304d8dbff42feb8c9693a0
Autor:
Yanjiao Shao, Canzhao Liu, Hsin-Kai Liao, Ran Zhang, Baolei Yuan, Hanyan Yang, Ronghui Li, Siting Zhu, Xi Fang, Concepcion Rodriguez Esteban, Ju Chen, Juan Carlos Izpisua Belmonte
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure. Multiple identified mutations in nexilin (NEXN) have been suggested to be linked with severe DCM. However, the exact association between multiple muta
Externí odkaz:
https://doaj.org/article/11999baaed2c4ab9b5d8511020581917
Autor:
Changming Tan, Siting Zhu, Zee Chen, Canzhao Liu, Yang E Li, Mason Zhu, Zhiyuan Zhang, Zhiwei Zhang, Lunfeng Zhang, Yusu Gu, Zhengyu Liang, Thomas G Boyer, Kunfu Ouyang, Sylvia M Evans, Xi Fang
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009785 (2021)
Dysregulation of cardiac transcription programs has been identified in patients and families with heart failure, as well as those with morphological and functional forms of congenital heart defects. Mediator is a multi-subunit complex that plays a ce
Externí odkaz:
https://doaj.org/article/18fca6d6e79348038660f42598de6a01
Autor:
Canzhao Liu, Simone Spinozzi, Wei Feng, Ze’e Chen, Lunfeng Zhang, Siting Zhu, Tongbin Wu, Xi Fang, Kunfu Ouyang, Sylvia M. Evans, Ju Chen
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
Nexilin (NEXN) was recently identified as a component of the junctional membrane complex required for development and maintenance of cardiac T-tubules. Loss of Nexn in mice leads to a rapidly progressive dilated cardiomyopathy (DCM) and premature dea
Externí odkaz:
https://doaj.org/article/a6fb1c606d9645daa3a6c9efdfbb0ac2
Autor:
Jennifer Veevers, Elie N. Farah, Mirko Corselli, Alec D. Witty, Karina Palomares, Jason G. Vidal, Nil Emre, Christian T. Carson, Kunfu Ouyang, Canzhao Liu, Patrick van Vliet, Maggie Zhu, Jeffrey M. Hegarty, Dekker C. Deacon, Jonathan D. Grinstein, Ralf J. Dirschinger, Kelly A. Frazer, Eric D. Adler, Kirk U. Knowlton, Neil C. Chi, Jody C. Martin, Ju Chen, Sylvia M. Evans
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 828-841 (2018)
Summary: To facilitate understanding of human cardiomyocyte (CM) subtype specification, and the study of ventricular CM biology in particular, we developed a broadly applicable strategy for enrichment of ventricular cardiomyocytes (VCMs) derived from
Externí odkaz:
https://doaj.org/article/130cb26d040c415ba92bc654a197ec5a
Autor:
Adam J Pollak, Canzhao Liu, Aparna Gudlur, Joshua E Mayfield, Nancy D Dalton, Yusu Gu, Ju Chen, Joan Heller Brown, Patrick G Hogan, Sandra E Wiley, Kirk L Peterson, Jack E Dixon
Publikováno v:
eLife, Vol 7 (2018)
Ca2+ signaling is important for many cellular and physiological processes, including cardiac function. Although sarcoplasmic reticulum (SR) proteins involved in Ca2+ signaling have been shown to be phosphorylated, the biochemical and physiological ro
Externí odkaz:
https://doaj.org/article/ecc097f1b4894d6997ab24d9a2cc0ed7
Autor:
Tongbin Wu, Zhengyu Liang, Zengming Zhang, Canzhao Liu, Lunfeng Zhang, Yusu Gu, Kirk L. Peterson, Sylvia M. Evans, Xiang-Dong Fu, Ju Chen
Publikováno v:
Circulation, vol 145, iss 8
Circulation
Circulation
Background: Left ventricular noncompaction cardiomyopathy (LVNC) was discovered half a century ago as a cardiomyopathy with excessive trabeculation and a thin ventricular wall. In the decades since, numerous studies have demonstrated that LVNC primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3832f3e1fed0e2280cbd5459b4ba07
https://escholarship.org/uc/item/5z39x1rx
https://escholarship.org/uc/item/5z39x1rx
Publikováno v:
Cell Proliferation
Objectives Recent studies revealed LRRC8A to be an essential component of volume‐regulated anion channel (VRAC), which regulates cellular volume homeostasis. However, evidence for the contribution of LRRC8A‐dependent VRAC activity in vascular smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17605268a82e4a65164174e890ecd5d3
https://doi.org/10.1111/cpr.13146
https://doi.org/10.1111/cpr.13146
Publikováno v:
Circulation: Heart Failure. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d6b5c50bb5ab8ea5c1c5885424669e
https://doi.org/10.1161/circheartfailure.121.008665
https://doi.org/10.1161/circheartfailure.121.008665
Publikováno v:
Circulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbea316096b7293c3881497f5bab4cd
https://doi.org/10.1161/circulationaha.119.043434
https://doi.org/10.1161/circulationaha.119.043434