Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Cantharidic acid"'
Autor:
Yu-Ting Ho, Shun-Fa Yang, Yi Ching Chen, Wei-En Yang, Pei-Ni Chen, Chun-Yi Chuang, Chiao-Wen Lin
Publikováno v:
Environmental Toxicology. 35:619-627
Cantharidic acid (CA) is the hydrolysis product of the acid anhydride cantharidin, which is a natural toxin secreted by several species of blister beetles. Several studies have indicated that as an inhibitor of protein phosphatase 2 (PP2A), CA induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba85cacce212c715ccbeefcbd082b191
https://doi.org/10.1002/tox.22897
https://doi.org/10.1002/tox.22897
Autor:
Lin Sun, Huanping Wei, Liwang Cui, Yaming Cao, Mingyang Hong, Yang He, Xiaotong Zhu, Qingyang Liu, Fei Liu
Publikováno v:
Int J Parasitol
Sexual development in malaria parasites involves multiple signal transduction pathways mediated by reversible protein phosphorylation. Here, we functionally characterized a protein phosphatase, Ser/Thr protein phosphatase 5 (PbPP5), during sexual dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9827679ecb38d2754e8130233d542fbf
https://doi.org/10.1016/j.ijpara.2019.03.007
https://doi.org/10.1016/j.ijpara.2019.03.007
Akademický článek
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Autor:
Pei Ching Hsiao, Shih Chung Wang, Ming Hsien Chien, Jyh Ming Chow, Shun-Fa Yang, Hui Yu Chen, Chiao Wen Lin
Publikováno v:
Environmental toxicology. 33(4)
Cantharidin, a natural toxin from blister beetles, has shown potent anticancer activities on many solid tumor cells. Recently, cantharidin and its analogue, norcantharidin, were also shown to suppress nonsolid tumors such as chronic myeloid leukemia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594732a149e442ab2c59d1aa6639949e
https://pubmed.ncbi.nlm.nih.gov/29345422
https://pubmed.ncbi.nlm.nih.gov/29345422
Autor:
I-Che Feng, Chao-Bin Yeh, Pei-Ni Chen, Shun-Fa Yang, Yi-Hsien Hsieh, Hsin-Yu Ho, Ming-Ju Hsieh
Publikováno v:
Environmental toxicology. 33(3)
Cantharidin analogs exhibit anticancer activities, including apoptosis. However, the molecular mechanisms underlying the effects of cantharidic acid (CA), a cantharidin analog, on apoptosis in hepatocellular carcinoma (HCC) cells are unclear. Thus, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7feefb14ff25972873fb5ad1681e7c90
https://pubmed.ncbi.nlm.nih.gov/29159945
https://pubmed.ncbi.nlm.nih.gov/29159945
Autor:
Jin-Ao Duan, Zhi-Shu Tang, Dawei Qian, Bu-Chang Zhao, Hong-Bo Liu, Zhenhua Zhu, Ying Jiang, Yiwei Shi, Qin Cao
Publikováno v:
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 41(15)
To investigate the stability and the conversion rules of cantharidin and cantharidic acid contained in the Mylabris aqueous solution under different conditions. The contents of cantharidin and cantharidic acid under different conditions (pH, temperat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a2f78d3b9cc0085694b4e0dd4d2d15
https://pubmed.ncbi.nlm.nih.gov/28914023
https://pubmed.ncbi.nlm.nih.gov/28914023
Akademický článek
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Autor:
Mika Yasui, Risako Fujikawa, Sei Higuchi, Masato Nakatsuji, Kosuke Hayashi, Taichi Ikedo, Masayuki Yokode, Manabu Nagata, Manabu Minami
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(11)
Excessive activation of inflammatory macrophages drives the pathogenesis of many chronic diseases. EP4 receptor–associated protein (EPRAP) has been identified as a novel, anti-inflammatory molecule in macrophages. In this study, we investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93100ca24003e2f88fcf4718e8a24a0a
https://pubmed.ncbi.nlm.nih.gov/27799315
https://pubmed.ncbi.nlm.nih.gov/27799315
Autor:
Hans Jürgen Steinfelder, Iris Quentin, Mohammed Shaheen, Sylvia Kaap, Dereje Tamiru, Kurt Eger
Publikováno v:
Biochemical Pharmacology. 65:603-610
In the present study, we outlined the part of the molecule mediating the prominent pro-apoptotic effect of the Michael adduct of ascorbic acid with p-chloro-nitrostyrene, a new synthetic phosphatase inhibitor. The nitrostyrene (NS) moiety was identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a029f74eac2edc1c0ffe12253a913e
https://doi.org/10.1016/s0006-2952(02)01618-0
https://doi.org/10.1016/s0006-2952(02)01618-0
Autor:
Xue-Qing Yang, Yalin Zhang
Publikováno v:
Enzyme and microbial technology. 69
Glutathione S-transferases (GSTs) play a key role in detoxification of xenobiotics in organisms. However, their other functions, especially response to the natural toxin cantharidin produced by beetles in the Meloidae and Oedemeridae families, are le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd9caa771e69fcdca4bc3c6205f00ef
https://pubmed.ncbi.nlm.nih.gov/25640718
https://pubmed.ncbi.nlm.nih.gov/25640718